Free Republic
Browse · Search
General/Chat
Topics · Post Article

Skip to comments.

Study finds dopamine, biological clock link to snacking, overeating and obesity
phys.org ^ | 01/03/2020 | by University of Virginia

Posted on 01/04/2020 5:05:51 PM PST by BenLurkin

In a study published Thursday in the journal Current Biology, Güler and his colleagues demonstrate that the pleasure center of the brain that produces the chemical dopamine, and the brain's separate biological clock that regulates daily physiological rhythms, are linked, and that high-calorie foods—which bring pleasure—disrupt normal feeding schedules, resulting in overconsumption. Using mice as study models, the researchers mimicked the 24/7 availability of a high-fat diet, and showed that anytime snacking eventually results in obesity and related health problems.

Güler's team found that mice fed a diet comparable to a wild diet in calories and fats maintained normal eating and exercise schedules and proper weight. But mice fed high-calorie diets laden with fats and sugars began "snacking" at all hours and became obese.

Additionally, so-called "knockout" mice that had their dopamine signaling disrupted—meaning they didn't seek the rewarding pleasure of the high-fat diet—maintained a normal eating schedule and did not become obese, even when presented with the 24/7 availability of high-calorie feeds.

Güler said the human body, through thousands of years of evolution, is hard-wired to consume as much food as possible as long as it's available. He said this comes from a long earlier history when people hunted or gathered food and had brief periods of plenty, such as after a kill, and then potentially lengthy periods of famine. Humans also were potential prey to large animals and so actively sought food during the day, and sheltered and rested at night.

"We evolved under pressures we no longer have," Güler said. "It is natural for our bodies as organisms to want to consume as much as possible, to store fat, because the body doesn't know when the next meal is coming.

(Excerpt) Read more at phys.org ...


TOPICS: Food; Health/Medicine
KEYWORDS: biologicalclock; dopamine; overeating; snacking
Navigation: use the links below to view more comments.
first 1-2021-4041-60 next last

1 posted on 01/04/2020 5:05:51 PM PST by BenLurkin
[ Post Reply | Private Reply | View Replies]

To: BenLurkin

My wife has decreed that we are going on an 8/16 intermittent fasting regime starting next week. I’m actually OK with that.


2 posted on 01/04/2020 5:14:29 PM PST by House Atreides (Boycott the NFL 100% — PERMANENTLY)
[ Post Reply | Private Reply | To 1 | View Replies]

To: BenLurkin
mice fed a diet comparable to a wild diet in calories and fats maintained normal eating and exercise schedules and proper weight.

What's a "wild" diet? That can be taken more than one way.

3 posted on 01/04/2020 5:15:11 PM PST by wastedyears (The left would kill every single one of us and our families if they knew they could get away with it)
[ Post Reply | Private Reply | To 1 | View Replies]

To: BenLurkin

“Güler said the human body, through thousands of years of evolution, is hard-wired to consume as much food as possible as long as it’s available.”

Many people don’t get obese, in spite of the plenty. What’s wrong with them?


4 posted on 01/04/2020 5:15:25 PM PST by rightwingcrazy (;-,)
[ Post Reply | Private Reply | To 1 | View Replies]

To: BenLurkin
I broke FR Rules and read the link.

Headline is bogus.

The link at the end said "body clock" not "biological clock".

Study has nothing to do with heifers getting fat in their old age.

5 posted on 01/04/2020 5:16:15 PM PST by Deaf Smith (When a Texan takes his chances, chances will be taken that's fore sure)
[ Post Reply | Private Reply | To 1 | View Replies]

To: BenLurkin

Whoooey...


6 posted on 01/04/2020 5:18:20 PM PST by Jim W N (MAGA by restoring the Gospel of the Grace of Christ and our Free Constitutional Republic!)
[ Post Reply | Private Reply | To 1 | View Replies]

To: House Atreides
I can't do keto or Adkins....I need some carbs....I can't do Mediterranean, which was voted the best weight loss diet by some nutritionists a few days ago, because I like my meat....

the intermittent fasting ..I could do.....they say to start with moderation.....so maybe I'll try 12 hrs and then move slowly up to 14...

7 posted on 01/04/2020 5:24:03 PM PST by cherry
[ Post Reply | Private Reply | To 2 | View Replies]

To: wastedyears

“This diet’s wild, man!”


8 posted on 01/04/2020 5:24:27 PM PST by Jeff Chandler (BLACK LIVES MAGA)
[ Post Reply | Private Reply | To 3 | View Replies]

To: BenLurkin
But mice fed high-calorie diets laden with fats and sugars began "snacking" at all hours and became obese.

Hidden in this sentence is the real culprit. The word is highlighted. Another word for food sugar is carbs.

9 posted on 01/04/2020 5:24:30 PM PST by Boomer ('Democrat' is now synonymous with 'corrupt')
[ Post Reply | Private Reply | To 1 | View Replies]

To: rightwingcrazy
Many people don’t get obese, in spite of the plenty.

Freaks.

10 posted on 01/04/2020 5:25:11 PM PST by Jeff Chandler (BLACK LIVES MAGA)
[ Post Reply | Private Reply | To 4 | View Replies]

To: BenLurkin

I notice my pattern is when I’m relaxed, I eat less regardless of how food is available. I notice that when I’m paying attention to how my body feels, I eat less regardless of how much food is available.


11 posted on 01/04/2020 5:25:32 PM PST by Jim W N (MAGA by restoring the Gospel of the Grace of Christ and our Free Constitutional Republic!)
[ Post Reply | Private Reply | To 1 | View Replies]

To: BenLurkin

These people no longer have any credibility as far as I am concerned. The have been consistently wrong for fifty years and continue to let political agendas drive their”science.”


12 posted on 01/04/2020 5:27:51 PM PST by hopespringseternal
[ Post Reply | Private Reply | To 1 | View Replies]

To: Jeff Chandler

“Freaks.”

Responsible people are not freaks.

Weakness isn’t overcome by disparaging the strong.


13 posted on 01/04/2020 5:33:17 PM PST by coaster123 (XLV-MMXX)
[ Post Reply | Private Reply | To 10 | View Replies]

To: Jim W N

Stress and lack of sleep mess me up.


14 posted on 01/04/2020 5:33:36 PM PST by EEGator
[ Post Reply | Private Reply | To 11 | View Replies]

To: BenLurkin

I need to quit having so many intimate dinners for two with just me showing up.


15 posted on 01/04/2020 5:35:29 PM PST by umgud
[ Post Reply | Private Reply | To 1 | View Replies]

To: coaster123; Jeff Chandler

Did you read the post he was replying to?


16 posted on 01/04/2020 5:37:22 PM PST by EEGator
[ Post Reply | Private Reply | To 13 | View Replies]

To: umgud

Just vomit after you eat too much.
Do some cocaine, and take up smoking.


17 posted on 01/04/2020 5:40:01 PM PST by EEGator
[ Post Reply | Private Reply | To 15 | View Replies]

To: cherry

I did 12/12 (very easy) with the intention of adding 15 minutes per day. After 3 days it was effortless to go to 14/10 and then 16/8 a few days later.


18 posted on 01/04/2020 5:41:56 PM PST by bankwalker (Immigration without assimilation is an invasion.)
[ Post Reply | Private Reply | To 7 | View Replies]

To: rightwingcrazy

Many people don’t get obese, in spite of the plenty. What’s wrong with them?
************************************
Tapeworms? ;-)


19 posted on 01/04/2020 5:42:57 PM PST by House Atreides (Boycott the NFL 100% — PERMANENTLY)
[ Post Reply | Private Reply | To 4 | View Replies]

To: coaster123
Responsible people are not freaks.

Okay. Oddballs.

20 posted on 01/04/2020 5:42:59 PM PST by Jeff Chandler (BLACK LIVES MAGA)
[ Post Reply | Private Reply | To 13 | View Replies]


Navigation: use the links below to view more comments.
first 1-2021-4041-60 next last

Disclaimer: Opinions posted on Free Republic are those of the individual posters and do not necessarily represent the opinion of Free Republic or its management. All materials posted herein are protected by copyright law and the exemption for fair use of copyrighted works.

Free Republic
Browse · Search
General/Chat
Topics · Post Article

FreeRepublic, LLC, PO BOX 9771, FRESNO, CA 93794
FreeRepublic.com is powered by software copyright 2000-2008 John Robinson