Posted on 04/19/2018 10:37:13 AM PDT by Red Badger
SCIENTISTS have controversially yet successfully grown part of a human brain inside a mouse and the organ even managed to survive for months in a major scientific breakthrough. ____________________________________________________________________________________________________________
For the first ever time miniature human brains have grown in a new species and scientists have suggested the breakthrough could help with stem cell research.
Scientists created the pin-sized human brains from stem cells and then placed them inside the skulls of mice, where a piece of tissue had been removed to make room for the new organ.
Of the test mice, roughly 80 percent survived the operation, and within two weeks the rodents implants had been successfully received and were even spawning new neurons.
The brain implants survived for an average of 233 days, but began the process of dying much earlier.
Lead researcher Fred Gage, a neuroscientist at the Salk Institute, said: "In our hands, the organoids stop growing around five weeks.
"It's a function of size rather than time. We see some cell death even in the edge of the organoids starting at 10 weeks, which becomes really dramatic over time.
This is an obvious hurdle for longtime study."
Abed Al-Fattah Mansour, a research associate at the Salk Institute, said: "That was a big accomplishment.
We saw infiltration of blood vessels into the organoid and supplying it with blood, which was exciting because it's perhaps the ticket for organoids' long-term survival.
In this exercise, the scientists accomplished three things installing an organoid into a complex tissue environment, connecting it to the species and integrating it into the cardiovascular system of the organism.
The researchers say the breakthrough could one day help with repairing organs such as brains from stem cells.
Mr Mansour added: These three elements are important for both basic research and drug discovery of brain disorders; for example, our approach has the potential for pre-clinical drug testing of patient-specific derived brain organoids under the organism setup.
"In addition, long-term survival could help the organoid to develop beyond the present embryonic stages that we see in culture.
"We hope this technology will set the stage and help to understand the pathogenesis of neurodevelopmental, neuropsychiatric and neurodegenerative disorders by enabling the generation of brain organoids from patients' own stem cells, transplanted into rodents.
-PJ
as if the little bastids aren’t clever enough the way it is...
The Rats of NIHM
Forget “Planet of the Apes” Prepare instead for “Planet of the Mice.”
Sorry....this is sick...
Mixed-up posts on the cutting room floor:
“Human-mouse HYBRID: Scientists grow human brain in tiny rodent for Pizza Rat 1, Mayor de Blasio 0
New York City Mayor Bill de Blasio is on a campaign to wipe
out the large populations of rats that plague the city and,
to replace them with rats with human brains. This will get
the brainy rats out of the sewers and into the housing projects,which aren`t that much better than the sewers,
“But what the hell! We gotta do something!” said de Blasio.
This will allow for a 1,000,000 percent increase in more
space available in the housing projects
The locusts looked like horses prepared for battle. On their heads they wore something like crowns of gold, and their faces resembled human faces. Their hair was like womens hair, and their teeth were like lions teeth. They had breastplates like breastplates of iron, and the sound of their wings was like the thundering of many horses and chariots rushing into battle. They had tails with stingers, like scorpions, and in their tails they had power to torment people for five months. They had as king over them the angel of the Abyss, whose name in Hebrew is Abaddon and in Greek is Apollyon (that is, Destroyer).
To defeat a rat, first you must be smarter than the rat.....................
Story from 18 years ago. Named it David Hogg.
Looks like these NY idiots could use a rat brain as they look clueless.
Of course...will be therapeutic at first....but then....can you imagine a soldier with the strength of a large chimp...and a devious mind of a human..or a group of jaguars with the pack mentality and ferociousness of a pit bull..
We’ll be totally safe with no guns....maybe they will eat the feral Hoggs.
“Sorry....this is sick...”
Sounds like ‘just because we can’.
That explains it. I guess something went terribly wrong.
My first thought as well. Eek, a mouse!
These brain organoids are very small and not conscious, but they create enough differentiated tissue to allow for the study of human brain diseases that were not possible before.
Adult stem cells are used, usually from the skin. Whatever happened to embryonic stem cells? Remember what a stink corrupt Democrats and crooked journalists made about them?
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