TAVR compared to SAVR in intermediate risk patients with aortic stenosis

News Medical Life Sciences ^ | November 1, 2017 | Dr. David J. Cohen

[Utah Binger]

Analysis of the PARTNER 2A trial and the SAPIEN-3 Intermediate Risk registry found transcatheter aortic valve replacement (TAVR) to be highly cost-effective compared with surgical aortic valve replacement (SAVR) in intermediate surgical risk patients with aortic stenosis.

Findings were reported today at the 29th annual Transcatheter Cardiovascular Therapeutics (TCT) scientific symposium. Sponsored by the Cardiovascular Research Foundation (CRF), TCT is the world's premier educational meeting specializing in interventional cardiovascular medicine.

Researchers led by Dr. David J. Cohen (Saint Luke's Mid America Heart Institute, Kansas City, MO) used data from the PARTNER 2A randomized trial and the SAPIEN-3 Intermediate Risk registry to perform a formal, patient-level economic analysis comparing TAVR using either the SAPIEN XT valve (XT-TAVR) or the SAPIEN-3 valve (S3-TAVR) with SAVR. The comparison between XT-TAVR and SAVR was based upon randomized assignment within PARTNER 2A; the comparison between S3-TAVR and SAVR was not randomized. Procedural costs were assessed based on measured resource utilization and all other costs were assessed by linking trial data with Medicare claims for the index hospitalization and follow-up period or by piecewise regression models for the remaining patients. "If we used purely volume-based criteria to judge hospitals good or bad, we would misclassify nearly 45 percent of all hospitals in the U.S.," said senior author Dr. Dharam Kumbhani, Assistant Professor of Internal Medicine at UT Southwestern Medical Center. "We found that, contrary to many older studies, there was a very weak association of hospital annual volumes with risk-adjusted outcomes for these procedures."

[Elsie]

Thanks. You guys have had much more done than I.

I’m on my second pacemaker. My sinus node was merely slowing down.

It must be getting close to receive a third, as I’ve had this one for 9+ years.

I got it 3 days before we got 4 baby goats at the farm.

[Elsie]

I’m trying to get my bovine valve to last as long as possible so my next one can be done by catheter.

HAY!!

[Elsie]

And I prayed like crazy.

You must not be ready to go yet ;^)

Too many things to do; I'll bet.

When I draw near to the end of my bucket list; I'll add more stuff just to keep going!