Posted on 08/02/2013 2:18:56 PM PDT by neverdem
Note: USC researcher Kathleen Page, MD, is an SC CTSI KL2 Alumnae. As part of the program, she recieved support and acquired skills needed to secure a subsequent K23 Career Training Award to continue this research.
Feeling hungry after drinking something sweet? It could have something to do with the type of sugar you consumed, according to research at Yale University led by SC CTSI K Scholar Kathleen Page, principal investigator and assistant professor of medicine at the USC Keck School of Medicine.
The research determined that fructose and glucose, the two forms of simple sugars, are processed differently in the brain. The difference was apparent after study participants consumed drinks containing fructose or glucose, and is a potential explanation for why we gain weight.
“We saw that fructose did not cause feelings of fullness, whereas the participants reported an increase in feelings of fullness after the glucose drink,” said Page, who is also chair of the Maternal-Child Health section of the USC Diabetes and Obesity Research Institute.
The research was published in the Journal of the American Medical Association, and was conducted while Page was on faculty at Yale. Research funding was provided by the Doris Duke Charitable Foundation.
The American Association for the Advancement of Science has posted a podcast of Page discussing the research.
The study used functional magnetic resonance imaging to map changes in the brains of 20 test subjects who consumed sugary drinks. The researchers found that the glucose drink suppressed activity in the hypothalamus and other brain regions that regulate appetite, motivation and reward processing, while the fructose drink did not. The different responses to fructose were associated with reduced levels of the hormone insulin, which sends signals to the brain that a person has had enough to eat.
Fructose, found with glucose in many fruits and vegetables, as well as table sugar, is an ingredient in high-fructose corn syrup, a popular sweetener. High-fructose corn syrup is found in certain soft drinks and processed foods, and consumption of the sweetener has been on the rise over the past few decades. Rates of obesity have increased in parallel, the researchers noted.
In continuing research, Page’s team is studying whether obese people have exaggerated brain reward and hunger responses to fructose and whether different ethnic groups respond differently to fructose and glucose.
The original article was published on the Keck School of Medicine website
Glucose-Fructose increases appetitie -- Leads to overeating
When you eat 120 calories of glucose, less than one calorie is stored as fat. 120 calories of fructose results in 40 calories being stored as fat.I found the last link first. The blockquote appears to come from Dr. Robert Lustig. When I Googled it I got 26,900 results.
This can’t be true, after all the corn mega-biz insists “sugar is sugar”.
I think we have a long way to go in learning what causes weight gain.
translation: Eat sugar, get fat
My reading is the body just sees the sugar. Doesn’t care where it came from - fruit, refined sugar, corn, veggies ...
So now food "BE RAYCISS"
OH? REALLY? I AM SHOCKED!.....
One thing to be aware of, before using this study to justify anti-corn syrup hysteria, is that fructose is not the same as “high fructose corn syrup”, and glucose is not the same as sucrose. HFCS has pretty much the same amounts of fructose and glucose that sucrose does. So if you think that drinks made with sucrose rather than HFCS will not display the same effect described in this article, you would be mistaken.
I think this is ripe for a “duh alert”
I agree.
I have been “eating clean” for a few years now. The amount of crap a/k/a, chemicals, sodium & fructose that they put in prepared foods would make your head spin.
Mine is usually because I’ve been a pee-eye-gee hog. I wish I could blame my fluctuations on something else.
I suspect that eating fattening foods makes you fat.
I know what makes me gain weight fastest and that’s milk and enriched white flour.
That 's not necessarily so. Before I checked into it I used to believe that too. Soft drinks are supposed to be 55% fructose, 42% glucose and 3% other sugars. 56:42 is the same as 4:3, but the actual HFCS can be as high as 65% fructose.
The fMRI study showed differences between pure glucose and pure fructose in cerebral blood flow. The hormonal studies explain why fructose does not promote a sense of feeling full.
Yet, instead of using real sugar, food is still packed with high fructose corn syrup. and she probably got big tax dollar funding to tell us all of this. why, this is PhD thesis stuff. Forgive my cynicism, its running on overtime these past 5 years...
And, SCCTSI, look professional. Use a damn spell checker. They are included free with most word processing programs.
And why is it popular?
Because for decades Americans have paid generally more than twice the world price for sugar, due to tariffs intended to protect American sugar cane and sugar beet farmers from competition. HFCS therefore becomes much more attractive price-wise than it would be without the tariffs.
So for a single policy we get to: A. pay twice the price for sugar; B. destroy the Everglades; and; C. become obsese.
Hooray for protective tariffs!
But I'd still hit it.
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