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Targeted blocking of cell death prevents fatal condition septic shock
VIB (the Flanders Institute for Biotechnology) ^ | December 27, 2011

Posted on 12/27/2011 7:00:50 AM PST by decimon

Ghent, Belgium 27 December 2011 - Researchers of VIB and UGent have discovered a new approach to preventing septic shock, an often fatal extreme inflammatory reaction of the body. It is the most frequent cause of death at intensive care departments in hospitals. In sepsis, acute inflammation is attended by low blood pressure and blood clots, causing the organs to stop working. Only recently, the Brazilian football legend Socrates, died of the consequences of this condition. In a new study in the top journal Immunity, Peter Vandenabeele and colleagues of VIB-UGent described how blocking a particular form of cell death (necroptosis) fully protects mice against this fatal inflammation.

"This research opens up new perspectives for the treatment of fatal inflammatory diseases such as sepsis," says researcher Peter Vandenabeele of VIB and UGent. "By blocking necroptosis, we have found a possibly new target for a therapy."

(Excerpt) Read more at eurekalert.org ...


TOPICS: Health/Medicine; Science
KEYWORDS:

1 posted on 12/27/2011 7:00:55 AM PST by decimon
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To: neverdem; DvdMom; grey_whiskers; Ladysmith; Roos_Girl; Silentgypsy; conservative cat; ...

Ping


2 posted on 12/27/2011 7:01:32 AM PST by decimon
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To: decimon

Wow, this is an amazing discovery!


3 posted on 12/27/2011 7:17:39 AM PST by The_Media_never_lie
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To: decimon

Wow! That’s sounds like a very beneficial discovery! Very cool.


4 posted on 12/27/2011 7:19:27 AM PST by LibertyRocks
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To: LibertyRocks
Indeed. My Dad passed away from sepsis...very overwhelming condition; everything just shuts down.

Any treatment that can effectively treat this would be great.

5 posted on 12/27/2011 7:59:17 AM PST by Victor (If an expert says it can't be done, get another expert." -David Ben-Gurion, the first Prime Minister)
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To: decimon

Wow. My husband died in 2010 of septic shock.


6 posted on 12/27/2011 8:00:38 AM PST by girlangler (Fish Fear Me)
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To: decimon

About three or four months ago we added a new test in our Laboratory at the hospital we work at and it is so wonderful to be able to tell if the patient is septic in an hr compared to 48 hr with the old Blood culture technic.. But we have had young people in the thirties die of Sepsis. Very sad.


7 posted on 12/27/2011 11:48:25 AM PST by crazydad
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To: crazydad

Glad the new test can tell. I kept asking hospital staff why hubby’s arm was swelled, then they transported him by ambiance to a bigger hospital and before it was over, his whole body was swollen.


8 posted on 12/27/2011 5:59:56 PM PST by girlangler (Fish Fear Me)
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