Free Republic
Browse · Search
General/Chat
Topics · Post Article

Skip to comments.

A Natural Dye Obtained from Lichens May Combat Alzheimer’s Disease
Max Delbrück Center for Molecular Medicine ^ | December 2, 2011

Posted on 12/02/2011 10:10:08 AM PST by decimon

A red dye derived from lichens that has been used for centuries to color fabrics and food appears to reduce the abundance of small toxic protein aggregates in Alzheimer’s disease. The dye, a compound called orcein, and a related substance, called O4, bind preferentially to small amyloid aggregates that are considered to be toxic and cause neuronal dysfunction and memory impairment in Alzheimer’s disease. O4 binding to small aggregates promotes their conversion into large, mature plaques which researchers assume to be largely non-toxic for neuronal cells. Further research with animal models is needed to determine whether this new approach by Dr. Jan Bieschke (Max Delbrück Center for Molecular Medicine, MDC, Berlin-Buch), Dr. Martin Herbst (Charité – Universitätsmedizin Berlin) and Professor Erich Wanker (MDC) in Berlin, Germany, will be useful for therapy development (Nature Chemical Biology, doi:

(Excerpt) Read more at mdc-berlin.de ...


TOPICS: Food; Health/Medicine; Science
KEYWORDS: alzheimers; lichens; reddye

1 posted on 12/02/2011 10:10:11 AM PST by decimon
[ Post Reply | Private Reply | View Replies]

To: neverdem; DvdMom; grey_whiskers; Ladysmith; Roos_Girl; Silentgypsy; conservative cat; ...

Ping


2 posted on 12/02/2011 10:11:43 AM PST by decimon
[ Post Reply | Private Reply | To 1 | View Replies]

To: decimon

3 posted on 12/02/2011 10:15:05 AM PST by JoeProBono (A closed mouth gathers no feet - Mater tua caligas gerit)
[ Post Reply | Private Reply | To 1 | View Replies]

To: decimon

A litmus test?


4 posted on 12/02/2011 10:21:54 AM PST by SuzyQue
[ Post Reply | Private Reply | To 1 | View Replies]

To: decimon

20 years of big pharma research on amyloid plaque has been
abandoned because preventing the plaque does not alter the
progression of the symptoms and cell death.


5 posted on 12/02/2011 10:35:22 AM PST by kruss3 (Kruss3@gmail.com)
[ Post Reply | Private Reply | To 1 | View Replies]

To: decimon

20 years of big pharma research on amyloid plaque has been
abandoned because preventing the plaque does not alter the
progression of the symptoms and cell death.


6 posted on 12/02/2011 10:35:42 AM PST by kruss3 (Kruss3@gmail.com)
[ Post Reply | Private Reply | To 1 | View Replies]

To: JoeProBono

You likin’ your lichen?


7 posted on 12/02/2011 10:37:04 AM PST by decimon
[ Post Reply | Private Reply | To 3 | View Replies]

To: kruss3
20 years of big pharma research on amyloid plaque has been abandoned because preventing the plaque does not alter the progression of the symptoms and cell death.

I'm not sure of what you're saying.

8 posted on 12/02/2011 10:44:09 AM PST by decimon
[ Post Reply | Private Reply | To 5 | View Replies]

To: decimon
I'm not sure of what you're saying.

Hell!he lost me at amyloid plaque! :P
9 posted on 12/02/2011 10:52:47 AM PST by gimme1ibertee ("Criticism......brings attention to an unhealthy state of things"-Winston Churchill)
[ Post Reply | Private Reply | To 8 | View Replies]

To: decimon

Harris Tweed! It does a body good!


10 posted on 12/02/2011 11:03:03 AM PST by WayneM (Two things are infinite: the universe and human stupidity; and I'm not sure about the the universe.)
[ Post Reply | Private Reply | To 1 | View Replies]

To: decimon

Big pharma has developed products that can completely prevent/remove the plaque. The alzheimer’s symptoms continue to worsen and the patient eventually dies.


11 posted on 12/02/2011 1:29:08 PM PST by kruss3 (Kruss3@gmail.com)
[ Post Reply | Private Reply | To 8 | View Replies]

Disclaimer: Opinions posted on Free Republic are those of the individual posters and do not necessarily represent the opinion of Free Republic or its management. All materials posted herein are protected by copyright law and the exemption for fair use of copyrighted works.

Free Republic
Browse · Search
General/Chat
Topics · Post Article

FreeRepublic, LLC, PO BOX 9771, FRESNO, CA 93794
FreeRepublic.com is powered by software copyright 2000-2008 John Robinson