Bkmk
I took cipro as did millions of others when anthrax was around. No problems.
Tendon rupture & peripheral neuropathy have been listed as adverse effects for years.
It seemed like Dr’s were handing out Cipro for everything, and in the past 2 or 3 years, they’ve cut back on prescribing it.
I’ve taken it in the past with no ill effects, but I wouldn’t take it now unless absolutely necessary.
It caused my right leg tendon to almost snap. It tore and healed and I have a lump there 20 years later, but I was lucky.
It’s a shame because it’s a really effective broad spectrum antibiotic.
This topic is way too complicated for here and probably whatever Dr you see.
That drug involves prostaglandins.
You may have genetic quirks related to that drug. Ignore people who come on here that says thousands used it with no problem. You appear to have a problem for whatever reason . Possibly genetic.
I had a bad reaction to a MRI contrast. I have no doubt that prostaglandins were part of it.
Prostaglandins are involved with the infamous niacin flush. I tried an experiment. Indomethacin knocked out the flush. You could try asking for indomethacin but it’s not a drug to take long term
You are going to have to do the research on this because you can’t rely on Drs to figure it out .
I have major genetic factors related to drugs and always look them up.
Check this site and look for anything you might have been taking at same time
https://go.drugbank.com/drugs/DB00537
Again....how old are you.
Been there, done that!
It was 2011..I had an infected tooth needing pulled from a bad root canal..he gave me cipro. Within 2 days the ligaments in my back blew out. Excruciating pain and I have been screwed up since. I have hyper mobile joints all over my body now.
Correct spelling of the drug: ciprofloxacin.
This sounds like the side effects from statins. This is why my wife can’t take them for these very side effects you mentioned.
I have CKD and cipro is the only thing I can take that cures any infection (especially UTI) quickly with no side effects. Other ABs just take my money and hover in the background.
My husband took cipro when he had some prostate biopsies, a few years ago. It has caused permanent neuropathy in his feet. Nothing we do helps much, and we have tried nearly everything. His tingling isn’t as bad as yours, but it is serious. We walk a few miles every day to make sure he doesn’t lose the ability to walk.
Now when they ask him about allergies, cipro is on the list. Never again.
They put this in the very fine print of a long document when you’re given it the first time. They are too nonchalant about it. It is yet another reason why I don’t trust big Pharma.
I sustained lots of nerve damage from chemo. Get a B-12 shot and then get little B-12,pills to dissolve undef your tongue.
From what I am reading from searches, you are likely experiencing two issues: ciprofloxacin-induced GABA receptor inhibition or NMDA receptor activation — both effect neuropathy.
Some things that are used to manage that resulting neurotransmitter imbalance:
Discontinuation of ciprofloxacin: Recovery can be slow or incomplete.
GABA support: Some use supplemental GABA, magnesium, or benzodiazepines (e.g., clonazepam) to enhance GABAergic activity and reduce neuronal excitability, though evidence is largely anecdotal.
Magnesium supplementation: May help restore the magnesium block of NMDA receptors, potentially reducing excitotoxicity.
Antioxidants and mitochondrial support: Given the role of oxidative stress in fluoroquinolone toxicity, N-acetylcysteine (NAC), CoQ10, and B vitamins are sometimes used.
Gut-brain axis support: Prebiotics may help restore microbial balance, indirectly supporting neurotransmitter regulation.
For tendon or tissue-related issues, which others get, these are caused by disruption of collagen synthesis (stoppage of new tissue generation) and increased matrix metalloproteinase (MMP) activity (an increase in what naturally breaks down tissue). This affects skin thickness and tendons, which rely on a couple different collagens (Type 1, overwhelmingly, and a little Type 3). (Joints use Type 2 collagen.)
There is also elastin that can help structurally with tissue rebuilding, but the only decent supplement I’ve found, is one we just recently started taking. It’s called “Elastin F.” It’s in “LABO Nutrition VesseCLEAR EX.”
I will say collagens we have been taking have helped a tendon issue (Achilles) and some internal and external tissues (primarily with skin surgery). These have studies available, as well. They are in “Sparkle Wellness FORTIGEL & TENDOFORTE Collagen Peptides / Collagen Powder” (TENDONFORTE is the tendon-tested component and the other is for joints) and Costco’s “Trunature Verisol Collagen Powder” (Verisol is the tested one—for skin tissue-type rebuilding).
The studies for the collagen show benefit within months. It appears stoppage keeps the benefit for some time, so these are semi-permanent changes.
Foods and supplements that curb the tissue breakdown by MMP include:
Flavonoids:
- Quercetin (onions, apples, berries, capers)
- Kaempferol (tea, broccoli, grapes)
- Luteolin (celery, parsley, artichokes)
- Myricetin (berries, tea, nuts)
- Apigenin (parsley, celery, chamomile)
Polyphenols and stilbenes:
- Resveratrol (grapes, red wine, berries)
- Pterostilbene (blueberries, grapes)
- EGCG (green tea)
- Oxyresveratrol (coconut shell waste)
Other plant-derived compounds:
- Sulforaphane (broccoli, cabbage)
- Curcumin (turmeric)
- Baicalein (Scutellaria root)
- Genistein (soy products)
- Silibinin (milk thistle)
- Eckol and dieckol (brown seaweed)
Foods supporting collagen synthesis:
- Vitamin C-rich foods (citrus, bell peppers, kiwi, broccoli)
- Collagen/gelatin sources (bone broth, chicken skin, fish)
- Zinc-rich foods (pumpkin seeds, oysters, beef)
- Copper-rich foods (nuts, seeds, shellfish)
- Omega-3 fatty acids (salmon, flaxseeds, walnuts)
“Drug X” caused an undesirable reaction the first time you took it, so you didn’t bother telling your physician about it when he prescribed it again ...
Folks: If you have some sort of undesirable reaction to “Drug X”, remember it. Write it down. Describe it. Tell your physician about it if it ever comes up again. Heck ... tell him/her/it/they/xe as soon as it happens. I did. That’s why I’m still breathing.
I had a serious joint sprain after taking Cipro that took three years of therapy to heal. Ironically, it was just after the 2001 anthrax scare about “white powder” being mailed to people, and the proposed treatment was Cipro, so like many people I had stockpiled a ten-day series of Cipro. My usage, however, had been for a sinus infection. I had to throw out my anthrax prophylaxis.
What makes you think it is from the drugs and not an allergy unique to you, your preexisting or an underlying condition?
Seems to me if you haven’t yet gone to the doctor that you are jumping to a conclusion.
My Dad got much better after taking it, but we also made sure to restore his gut bacteria both with supplements, yogurt and fermented foods.
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Cipro can be very harsh on the body or worse. I have been prescribed cipro twice for deep prostate infections. Primary side effects were joint pain, but that ended when I finished the script.
With said, the potential side-effects are serious and well publicized:
“Ciprofloxacin can cause serious side effects, including tendon problems, damage to your nerves (which may be permanent), serious mood or behavior changes (after just one dose), or low blood sugar (which can lead to coma).”
https://www.drugs.com/ciprofloxacin.html#side-effects
Wow. Are you sure it was the cipro?
Cipro is the only thing I can take for UTIs, and I feel better than I have in years.