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Posted on 10/07/2025 11:59:46 AM PDT by Red Badger
Scientists from the University of Oxford and the Chinese Academy of Medical Sciences (CAMS) have discovered a “kill switch” in human cells that is left behind after a COVID-19 virus infection.
The team of researchers published a bombshell new study showing that spike-specific helper T cells remain in the body years after COVID-19 infection.
Alarmingly, those cells undergo a troubling transformation over time.
The research, led by Dr. Guihai Liu and Professor Tao Dong, followed patients 3–4 years after infection.
The study revealed that these CD4+ T cells not only persisted but also morphed into a more aggressive, cytotoxic form.
This shift was marked by high expression of granzyme A (GZMA), a “kill-switch” enzyme that allows immune cells to attack targets directly.
While these reprogrammed cells appeared capable of suppressing the virus in lab experiments, the implications for human health remain unclear.
However, scientists warn that it could be a double-edged sword.
Persistent Fingerprints Linked to “Mild Disease”
One of the most striking findings was the presence of “public” T-cell receptor patterns, which are unique immune fingerprints shared across unrelated people.
These clonotypes were strongly linked with milder cases of COVID-19 early in the pandemic.
But by the 3–4 year mark, the same clonotypes showed major changes.
Instead of a balanced helper function, they had shifted toward a cytotoxic profile, blasting out GZMA in a way that scientists admitted could suppress the virus in vitro, but might not translate into safe or protective responses inside the body.
Vaccination Not Ruled Out
Although the study tracked people who had natural infection, most had also received multiple Covid shots or boosters during the follow-up years.
Researchers noted that they could not separate out the effects of vaccination from infection.
What they did confirm: the number of vaccine doses a person had did not correlate with the presence of these “public” immune fingerprints.
Still, they conceded that repeated vaccination and re-exposure could be driving the re-tuning of memory T cells toward this aggressive profile.
A Dangerous Wildcard?
Other studies have already flagged that cytotoxic CD4+ T cells can show up in severe COVID cases, damaging lung tissue rather than protecting it.
The Oxford paper cautiously suggested that in the long term, these cells might help control the virus, but admitted the clinical effects remain unknown.
Critics say this kind of immune reprogramming should raise red flags.
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Great BS detector you have,
My MD is Nigerian, went to med school there, where they are not funded by BigPharma. He literally prescribes a handful of nutritional supplements for me including Vitamin C. Been taking them for dozens of years. Had a cold once about 9 years ago. Broken bones are my only health prob, weigh 112, exercise every daty eat organic, no saturated fats or junk food. 89 now, MD expects me to live at least 100 years.
Old friend who did that ust died at 102 and she still looked great. Apparently I still do too. Friend Rick drove me over to his house on a nearby lake to meet his daughters who were visiting from Germany. They thought. Rick and I were the same age. I’’m 17 years older than he is.
They couldn’t make it two sentences without using ‘bombshell’.
Wear a mask.
AND at the reproductive medical center!
Oooops! Snipped 40+ years ago.
Nurse! My friend rktman is having a little trouble. Could you help him out please? :D
😂👍
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