Posted on 09/06/2024 5:28:55 AM PDT by Red Badger
A study led by The University of Texas at Austin has identified SC27, an antibody capable of neutralizing all known variants of the COVID-19 virus, opening prospects for universal vaccine development and improved treatments amid ongoing viral evolution.
Researchers have identified an antibody capable of neutralizing all known strains of SARS-CoV-2, the virus responsible for COVID-19, and several other SARS-like coronaviruses found in different animals.
As part of a new study on hybrid immunity to the virus, the large, multi-institution research team led by The University of Texas at Austin discovered and isolated a broadly neutralizing plasma antibody, called SC27, from a single patient. Using technology developed over several years of research into antibody response, the team led by UT engineers and scientists obtained the exact molecular sequence of the antibody, opening the possibility of manufacturing it on a larger scale for future treatments.
“The discovery of SC27, and other antibodies like it in the future, will help us better protect the population against current and future COVID variants,” said Jason Lavinder, a research assistant professor in the Cockrell School of Engineering’s McKetta Department of Chemical Engineering and one of the leaders of the new research, which was recently published in Cell Reports Medicine.
Evolution of COVID-19 and the Role of SC27
During the more than four years since the discovery of COVID-19, the virus that causes it has rapidly evolved. Each new variant has displayed different characteristics, many of which made them more resistant to vaccines and other treatments.
Protective antibodies bind to a part of the virus called the spike protein that acts as an anchor point for the virus to attach to and infect the cells in the body. By blocking the spike protein, the antibodies prevent this interaction and, therefore, also prevent infection.
SC27 recognized the different characteristics of the spike proteins in the many COVID variants. Fellow UT researchers, who were the first to decode the structure of the original spike protein and paved the way for vaccines and other treatments, verified SC27’s capabilities.
The technology used to isolate the antibody, termed Ig-Seq, gives researchers a closer look at the antibody response to infection and vaccination using a combination of single-cell DNA sequencing and proteomics.
Toward a Universal Vaccine “One goal of this research, and vaccinology in general, is to work toward a universal vaccine that can generate antibodies and create an immune response with broad protection to a rapidly mutating virus,” said Will Voss, a recent Ph.D. graduate in cell and molecular biology in UT’s College of Natural Sciences, who co-led the study.
In addition to the discovery of this antibody, the research found that hybrid immunity — a combination of both infection and vaccination — offers increased antibody-based protection against future exposure compared with infection or vaccination alone.
The work comes amid another summer COVID spike. This trend shows that while the worst of the pandemic may have passed, there’s still a need for innovative solutions to help people avoid and treat the virus.
Reference:
“Hybrid immunity to SARS-CoV-2 arises from serological recall of IgG antibodies distinctly imprinted by infection or vaccination” by William N. Voss, Michael L. Mallory, Patrick O. Byrne, Jeffrey M. Marchioni, Sean A. Knudson, John M. Powers, Sarah R. Leist, Bernadeta Dadonaite, Douglas R. Townsend, Jessica Kain, Yimin Huang, Ed Satterwhite, Izabella N. Castillo, Melissa Mattocks, Chelsea Paresi, Jennifer E. Munt, Trevor Scobey, Allison Seeger, Lakshmanane Premkumar, Jesse D. Bloom, George Georgiou, Jason S. McLellan, Ralph S. Baric, Jason J. Lavinder and Gregory C. Ippolito, 1 August 2024, Cell Reports Medicine.
DOI: 10.1016/j.xcrm.2024.101668
The researchers have filed a patent application for SC27. Other members of the team from UT are Jason McLellan, Patrick O. Byrne, Sean A. Knudson, Douglas R. Townsend, Jessica Kain, and Yimin Huang of the Department of Molecular Biosciences; George Georgiou, Ed Satterwhite, and Allison Seeger of the McKetta Department of Chemical Engineering; Jeffrey M. Marchioni of the Department of Biomedical Engineering; and Chelsea Paresi of the Department of Chemistry. Team members from other institutions include Greg Ippolito of the Texas Biomedical Research Institute; Ralph S. Baric, Michael A. Mallory, John M. Powers, Sarah R. Leist, Jennifer E. Munt and Trevor Scobey of the University of North Carolina at Chapel Hill’s Department of Epidemiology; Izabella N. Castillo, Melissa Mattocks and Premkumar Lakshmanane of UNC’s Department of Microbiology and Immunology; and Bernadeta Dadonaite and Jesse D. Bloom of Fred Hutchinson Cancer Center. The research team received funding from the National Institutes of Health and the Bill & Melinda Gates Foundation.
Ping!...................
Ping
I think I smell another money wasting vaccine scam
My standing rule is ten solid years of testing and research before I’ll even think about taking it.
That should shake out the dead bodies.
Yeah, no.
I don’t trust anything they’re hailing as a “Universal vaccine” ...
FTA ...
... During the more than four years since the discovery of COVID-19, the virus that causes it has rapidly evolved. Each new variant has displayed different characteristics, many of which made them more resistant to vaccines and other treatments...
Only .. it’s their untested, dangerous china virus jab that has caused all of these ‘rapidly evolving’ variants. We were told this is exactly what would be happening, by REAL docs/scientists, early on.
NO SALE!!
Coronaviruses have been around for thousands of years and will be around for thousands more.
“Newly Discovered Antibody Protects Against All COVID-19 Variants”
That’s a BOLD statement considering these viruses rapidly mutate.
I didn’t play their first game of Russian roulette, or any of their sequels. Ain’t about to trust them now.
SSDD.
It was a scam and the people behind it should be tried and executed. They are slow to all git until we forget what they did to us. I will never forget.
A link to the study. And that’s an...interesting read.
“My standing rule is ten solid years of testing and research before I’ll even think about taking it.”
I also wait for the first ten years of propaganda and mass brainwashing to happen.
That way we can be sure all the NPCs have taken the jab and multiple boosters.
Yeah ahh, okay.
This supposedly against all KNOWN variants - You can bet the “unknown” and “unexpected” variants will pop up in due time.
Also, how many boosters will be required to shore up big pharma’s income statement? Quarterly reports and all...
Do you have a synopsis for folks like me who aren’t medically adept?
My speed reading brakes need adjustment, I thought I saw it protects against all the covid vaccines. :/
bbb covid
Tried to access the article and saw this.
“This is a preprint.
It has not yet been peer reviewed by a journal.”
[[discovered and isolated a broadly neutralizing plasma antibody, called SC27, from a single patient]]
Did this single patient have previous MRNA shots and boosters? If so, will that affect the antibody and be transfered to people who refused to take the clot shots?
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