Posted on 04/10/2020 6:05:33 PM PDT by SeekAndFind
The new study, of which the abstract was released today, was performed at IHU Méditerranée Infection, Marseille, France. A cohort of 1061 COVID-19 patients, treated for at least 3 days with the Hydroxychloroquine-Azithromycin (HCQ-AZ) combination and a follow-up of at least 9 days was investigated.
Key findings are:
A poor outcome was observed for 46 patients (4.3%); 10 were transferred to intensive care units, 5 patients died (0.47%) (74-95 years old) and 31 required 10 days of hospitalization or more.
The authors conclude that:
The HCQ-AZ combination, when started immediately after diagnosis, is a safe and efficient treatment for COVID-19, with a mortality rate of 0.5%, in elderly patients. It avoids worsening and clears virus persistence and contagiosity in most cases.
See the complete abstract below.
The original abstract can be accessed here.
Also, the researchers made this table available.
It’s not clear when the complete study will be made available.
ABSTRACT
Background
In a recent survey, most physicians worldwide considered that hydroxychloroquine (HCQ) and azithromycin (AZ) are the two most effective drugs among available molecules against COVID-19. Nevertheless, to date, one preliminary clinical trial only has demonstrated its efficacy on the viral load. Additionally, a clinical study including 80 patients was published, and in vitro efficiency of this association was demonstrated.
The study was performed at IHU Méditerranée Infection, Marseille, France. A cohort of 1061 COVID-19 patients, treated for at least 3 days with the HCQ-AZ combination and a follow-up of at least 9 days was investigated. Endpoints were death, worsening and viral shedding persistence.
Findings
From March 3rd to April 9th, 2020, 59,655 specimens from 38,617 patients were tested for COVID-19 by PCR. Of the 3,165 positive patients placed in the care of our institute, 1061 previously unpublished patients met our inclusion criteria. Their mean age was 43.6 years old and 492 were male (46.4%). No cardiac toxicity was observed. A good clinical outcome and virological cure was obtained in 973 patients within 10 days (91.7%). Prolonged viral carriage at completion of treatment was observed in 47 patients (4.4%) and was associated to a higher viral load at diagnosis (p < 10-2) but viral culture was negative at day 10 and all but one were PCR-cleared at day 15. A poor outcome was observed for 46 patients (4.3%); 10 were transferred to intensive care units, 5 patients died (0.47%) (74-95 years old) and 31 required 10 days of hospitalization or more. Among this group, 25 patients are now cured and 16 are still hospitalized (98% of patients cured so far). Poor clinical outcome was significantly associated to older age (OR 1.11), initial higher severity (OR 10.05) and low hydroxychloroquine serum concentration. In addition, both poor clinical and virological outcomes were associated to the use of selective beta-blocking agents and angiotensin II receptor blockers (P<0.05). Mortality was significantly lower in patients who had received > 3 days of HCQ-AZ than in patients treated with other regimens both at IHU and in all Marseille public hospitals (p< 10-2).
The HCQ-AZ combination, when started immediately after diagnosis, is a safe and efficient treatment for COVID-19, with a mortality rate of 0.5%, in elderly patients. It avoids worsening and clears virus persistence and contagiosity in most cases.
to vaccine-adamant Fauci,
this means nothing. it is anecdotal.
NOTHING will stand in the way of Fauci-Gates-Soros
and their malicious plan infecting Earth.
Excellent.
How many hacking attempts are underway right now to get into the files of IHU Méditerranée Infection in order to find some connection to Trump?
It’s a pretty big anecdote.
Enemedia will scream: “See, we told you so, it’s a deadly drug. It killed 4.3% of patients!”
Dr Didier has been doing his part to “social distance” from barbers for years.
Mortality was significantly lower in patients who had received > 3 days of HCQ-AZ than in patients treated with other regimens both at IHU and in all Marseille public hospitals (p< 10^(-2)).
It sounds very promising. If I'm reading it right, they are saying there is less than 1 in 100 chance the results happened by chance alone.
However it's a bit weird that they don't put that fact right up at the top, and they don't give any numbers for the comparison, i.e. among those patients not treated with HCQ, the death rate was 2% or 1% or whatever.
Consider that drugs touted as miracle cures often work on less than half the trial folks and have many serious, serious side effects.
Of course muppet media doesn’t provide context.
Better to be anecdotally alive than scientifically dead!
That is very impressive.
Check out the news on this guy. He is getting a lot of heat. I can’t believe anything so obvious would be challenged like it is.
Dr Didier has been doing his part to social distance from barbers for years
Btt
Bkmk and ping.
It really is a sign of how insane and split our world has become. It’s in plain sight to see and yet the liberals and Trump haters are doing their darndest to discount the drug. It’s really unbelievable and there is no hope of reconciliation with the left
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