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What made humans 'the fat primate'?
phys.org ^ | 06/26/2019 | Robin A. Smith, Duke University

Posted on 06/27/2019 10:54:12 AM PDT by BenLurkin

While other primates have less than 9% body fat, a healthy range for humans is anywhere from 14% to 31%.

Using a technique called ATAC-seq, they scanned each species' genome for differences in how their fat cell DNA is packaged.

Normally most of the DNA within a cell is condensed into coils and loops and tightly wound around proteins, such that only certain DNA regions are loosely packed enough to be accessible to the cellular machinery that turns genes on and off.

The researchers identified roughly 780 DNA regions that were accessible in chimps and macaques, but had become more bunched up in humans. Examining these regions in detail, the team also noticed a recurring snippet of DNA that helps convert fat from one cell type to another.

Not all fat is created equal... Most fat is made up of calorie-storing white fat. It's what makes up the marbling in a steak and builds up around our waistlines.

Specialized fat cells called beige and brown fat, on the other hand, can burn calories rather than store them to generate heat and keep us warm.

One of the reasons we're so fat, the research suggests, … is because the regions of the genome that help turn white fat to brown were essentially locked up...in humans but not in chimps.

Humans, like chimps, need fat to cushion vital organs, insulate us from the cold, and buffer us from starvation. But early humans may have needed to plump up for another reason, the researchers say—as an additional source of energy to fuel our growing, hungry brains.

The human brain uses more energy, pound for pound, than any other tissue. Steering fat cells toward calorie-storing white fat rather than calorie-burning brown fat, the thinking goes, would have given our ancestors a survival advantage.

(Excerpt) Read more at phys.org ...


TOPICS: Health/Medicine
KEYWORDS: fat; sugar
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To: BenLurkin

Capitalism!


21 posted on 06/27/2019 11:12:03 AM PDT by null and void (Stamp out philately!)
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To: BenLurkin

I recently told my doctor:

“I’m not fat. I’m just easy to see.”

Without losing a beat, he said:

“I want to see less of you the next time we meet.”

I had all kinds of neat comebacks...as I got into my car in the parking lot.


22 posted on 06/27/2019 11:12:58 AM PDT by econjack
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To: BenLurkin

Years ago, there was a popular theory that humans were descendants of aquatic apes who were accustomed to living and hunting in shallow lakes and along shorelines, instead of on the savanna. Many of our unique features could be attributed to that, including our ability to control breathing, our dive reflex, and our subcutaneous layer of fat which insulates us from greater heat loss when surrounded by water. I don’t know what became of the notion, but it purported to explain many odd things about us.


23 posted on 06/27/2019 11:13:03 AM PDT by PUGACHEV
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To: Boogieman

Common sense. My great aunt fed her dog all the time.. It was Fat Fat Fat...


24 posted on 06/27/2019 11:13:07 AM PDT by taterjay
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To: 9YearLurker

25 posted on 06/27/2019 11:13:14 AM PDT by BenLurkin (The above is not a statement of fact. It is either opinion or satire. Or both.)
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To: econjack

That’s funny!


26 posted on 06/27/2019 11:13:40 AM PDT by BenLurkin (The above is not a statement of fact. It is either opinion or satire. Or both.)
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To: gr8eman

Venezualans have lost weight the past 2 years.


27 posted on 06/27/2019 11:14:15 AM PDT by taterjay
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To: gr8eman

Primate literally means the first (or primary) kind. As a primate, I’m numba one, you numba ten, as you say...


28 posted on 06/27/2019 11:14:50 AM PDT by null and void (Stamp out philately!)
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To: BenLurkin

Ha ha!

As I said, “many”:

https://stats.nba.com/draft/combine-anthro/


29 posted on 06/27/2019 11:14:50 AM PDT by 9YearLurker
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To: BenLurkin

The grocery store.


30 posted on 06/27/2019 11:16:25 AM PDT by fruser1
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To: BenLurkin

Welfare checks?


31 posted on 06/27/2019 11:18:29 AM PDT by Cowboy Bob ("Other People's Money" = The life blood of Liberalism)
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To: Spruce

Too many carbohydrates.


32 posted on 06/27/2019 11:21:46 AM PDT by 353FMG
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To: PUGACHEV

I don’t know what became of the notion, but it purported to explain many odd things about us.


I prefer the notion that we descended from tree dwelling apes. An environment of ready to eat fruit meant that the ability to synthesize vitamin C was no longer needed and withered away. That’s why my dog can make his own C, but I can’t.


33 posted on 06/27/2019 11:24:31 AM PDT by sparklite2 (Don't mind me. I'm just a contrarian.)
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To: libertylover

The meat is OK, the buns will make you fat and the chance for diabetes increases. Mankind can survive without ingesting carbs.


34 posted on 06/27/2019 11:25:03 AM PDT by 353FMG
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To: BenLurkin

31% body fat is OBESE!


35 posted on 06/27/2019 11:26:56 AM PDT by Mariner (War Criminal #18)
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To: BenLurkin
I think the real reason is that humans share a number of unique characteristics with whales, walruses and other aquatic mammals (a layer of fat being one of them - though by no means the only one). I have always thought that the Aquatic Ape hypothesis of human evolution, as described in Elaine Morgan's very interesting 1975 book The Descent of Woman makes a lot of sense.

For a summary of her thesis, check this article. It's eight pages long, but you don't have to read past the first page to get the main idea.

There are certainly those in the anthropology field who disagree with this hypothesis. But personally I think it offers a lot of answers that other theories don't.

36 posted on 06/27/2019 11:28:45 AM PDT by Maceman (Trump Trumps Hate!!!)
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To: BenLurkin
The real reason that we are fat is because food is inexpensive and plentiful due to human ingenuity and the mechanization of farming!


37 posted on 06/27/2019 11:28:53 AM PDT by wildcard_redneck (Freeper formerly known as WMarshal.......)
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To: sparklite2

Only humans, fruit bats, guinea pigs and primate monkeys do not synthesize vitamin C naturally.

CRISPR anyone?


38 posted on 06/27/2019 11:29:12 AM PDT by null and void (Stamp out philately!)
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To: Mariner
HEY! I resemble that remark!
39 posted on 06/27/2019 11:29:54 AM PDT by null and void (Stamp out philately!)
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To: taterjay

I bet that the diabetes rate has declined in that country.


40 posted on 06/27/2019 11:31:34 AM PDT by 353FMG
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