Posted on 12/06/2015 5:55:11 PM PST by Rebelbase
Abstract
The aging process is a universal phenomenon shared by all living organisms. The identification of longevity genes is important in that the study of these genes is likely to yield significant insights into human senescence.
In this study, we have identified Tequila as a novel candidate gene involved in the regulation of longevity in Drosophila melanogaster.
We have found that a hypomorphic mutation of Tequila (Teq f01792), as well as cell-specific downregulation of Tequila in insulin-producing neurons of the fly, significantly extends life span. Tequila deficiency–induced life-span extension is likely to be associated with reduced insulin-like signaling, because Tequila mutant flies display several common phenotypes of insulin dysregulation, including reduced circulating Drosophila insulin-like peptide 2 (Dilp2), reduced Akt phosphorylation, reduced body size, and altered glucose homeostasis. These observations suggest that Tequila may confer life-span extension by acting as a modulator of Drosophila insulin-like signaling.
(Excerpt) Read more at biomedgerontology.oxfordjournals.org ...
Great news, but becoming a Drosophila melanogaster is going to be tough for me at my age ...
The night before I quit drinking in 1989, I had been drinking tequila with friends and ordering marguritas by the pitcher.
;’)
cures insulin problems in flys?
It’s referring to a gene called, “tequila.”
Yes they really love my apple and pear cores. Now all we need to do is find out if there are people with the “hypomorphic mutation of Tequila (Teq f01792),”. Then we can test to see if folks with this gene have better insulin regulation with alcohol including tequila than folks who don’t have it.
Two shots of Tequila and I can dance, even those funny dances from Mexico like the cumbia.
Three shots of Tequila and I’m the life of the party.
Four shots of Tequila and I’m unbelievably handsome.
Five shots of Tequila and I’m a chick magnet, including wives of business associates and best friends.
Six shots of Tequila and I’m a real badass. Back off Federales!
Seven or more shots of Tequila and I’m invisible and bulletproof.
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