Ebola Surveillance Thread

(Dallas County Commissioner) John Wiley Price Suggests Race A Factor In Dallas Ebola Case

It takes a real piece of human excrement to take a situation like this and to insert race into it.

Mr. Price, the Ebola virus does not discriminate. It is an equal opportunity Level 4 contaminant.

From your mouth to God’s ear......people rabbiting on about certain groups spreading it.....Ebola does not give a crap who you are, all you are is a host to breed, replicate and infect.

It does not choose race, sexuality, social class, wealth or whether you are a nice person or not, all it cares about is killing you.

Spanish Nurse Found Out She Had Ebola Online

Liberia: Dead Ebola patients resurrect?

Latest Ebola victim sheriff’s deputy ordered to Duncan’s apartment without protective gear

wow cnn had a guy on said that there are 2 other Dallas deputies going in..

one guy drove Monnig’s car a day after Monnig..

Erin Burnett was so shocked that she cut him off.. I believe the man on the show is the president of Dallas Sheriffs Fraternal Order of Police.. or something like that.. but they are now downplaying it, have only heard them mention it once since..

I’ve been one of the doom & gloom posters here, so here is something different. We’ll beat Ebola with vaccines, and those are coming much faster in the developed countries than people think. The vaccines are being tested now, and can go into production within thirty days of the order being given. 200 million units can be produced in the ensuing five months just with existing American production facilities.

This is because vaccine production technology has improved. They don’t need to slowly produce it in chicken eggs. They produce it in machines using something called “cell culture”, which is explained in the first article published ten days ago. The second article, an op-ed in the Wall Street Journal last weekend, advocates starting production NOW without waiting for the trials to end. That is precisely what should be done.

I.e., everyone in America can be vaccinated against Ebola by the end of May 2015. Only the political will to do so is lacking.

I entirely agree with doubters that the government would rather all of us die than take the risk of being blamed for wasting (Gasp!) several hundred million dollars on vaccines that haven’t gone through 35 years of bureaucratic a**-saving paperwork. It’s our job to make them do it anyway.

The chief threat to our lives, the lives of our children, and the US economy are our incompetent me-first elected officials and the incompetent bureaucrats they appoint. It’s time to throw them all out any way we can, and the sooner the better.

Only then will any we miss be so terrified that they’ll start producing the vaccines we need to survive the coming Ebola epidemic.

Here are the articles showing how that will happen eventually. I repeat, it’s our job to force the government to start doing so sooner.

Note that the first generation of Ebola vaccines being tested as you read this all seem to require refrigeration, i.e., we can’t save Africa with those. But we can save the developed countries.

http://www.xconomy.com/raleigh-durham/2014/09/30/zmapp-ebola-drug-production-set-for-texas-possibly-north-carolina/

ZMapp Ebola Drug Production Set for Texas, Possibly North Carolina
September 30, 2014
Frank Vinluan9/30/14Follow @frankvinluan
A federal initiative to ensure that the United States can respond to biological threats at home will be put to the test in response to the Ebola outbreak in West Africa.
A Texas site is preparing to manufacture the experimental Ebola drug ZMapp, says Robin Robinson, director of the Biomedical Advanced Research and Development Authority (BARDA), a division within the U.S. Department of Health and Human Services. Robinson adds that Novartis’s (NYSE: NVS) vaccine facility in North Carolina is a possible second site to make the drug. Those sites were developed previously in partnership with a U.S. government effort to establish response centers capable of manufacturing drugs and vaccines in an emergency.
ZMapp, developed by San Diego-based biotech Mapp Biopharmaceutical, is a biological drug. The antibodies that spark the immune system are produced in tobacco plants, then extracted from the plant to make the drug. A Kentucky subsidiary of Reynolds American grew the tobacco plants that made the monoclonal antibodies in ZMapp. Robinson says BARDA is now working with a response center at Texas A&M University to bring the tobacco drug-making technology from Kentucky to Texas. The university and its industry partners will use that technology to make ZMapp.
“They would respond by making that product, then helping us through clinical trials, then taking it to where it’s needed,” Robinson says.
Robinson, who is also deputy assistant secretary for preparedness and response at HHS, was in North Carolina last week for a Novartis event marking the first shipments of seasonal flu vaccine from the company’s Holly Springs, NC, vaccine plant. He says new vaccine production technology that Novartis has implemented to make flu vaccines more quickly could also, if needed, be used to make biological drugs such as ZMapp. The government earlier this month committed up to $42.3 million to help Mapp Bio accelerate development and testing of its Ebola drug.
The idea of creating drug and vaccine manufacturing centers followed the global H1N1 influenza pandemic in 2009. The HHS awarded three contracts in 2012 to establish three centers, called Centers for Innovation and Advanced Development and Manufacturing. These centers, which would address threats from naturally occurring diseases as well as acts of bioterrorism, represent alliances between government, industry, and academia.
Texas A&M recently opened a pandemic influenza vaccine manufacturing facility in Bryan, TX—part of the response center it leads under a five-year $176 million contract. GlaxoSmithKline (NYSE: GSK) is the university’s largest industry partner. Emergent Manufacturing Operations Baltimore, which has Maryland sites in both Baltimore and Gaithersburg, leads another center under a $163 million contract over eight years; Emergent Manufacturing is working with Michigan State University, Kettering University in Flint, MI, and the University of Maryland, Baltimore.
And Novartis leads a response center at its vaccine manufacturing plant in Holly Springs, which was developed under a $60 million contract. This center operates in partnership with NC State University and Duke University. Novartis’s flu vaccine relationship with BARDA predates the formation of the three response centers. In 2006, BARDA awarded Novartis a contract valued at up to $220.5 million to develop a cell-based influenza vaccine.
In conceiving the response centers, the government emphasized both capacity and speed. Each center must be able to produce at least 50 million doses of pandemic flu vaccine within four months. The government also requires that the centers be able to deliver the first doses for distribution within 12 weeks. The reason for three centers is not for geographic diversity. While there is some overlap among the centers, each center has capabilities that set it apart from the others, Robinson explains.
The Novartis Holly Springs site stands apart because of new technology that can produce vaccines in animal cells through a process called cell culture. Flu vaccines have traditionally been produced by growing the virus in chicken eggs, which can take up to six months. Instead, Novartis’s Holly Springs plant makes flu vaccine from animal cells, specifically, a cell line from a dog’s kidney. This cell culture process takes about 30 days.
Novartis broke ground in Holly Springs in 2009. Two years later, the plant was ready for production. In June, the Food and Drug Administration licensed the Novartis facility to produce seasonal flu vaccine made from cell culture. This facility is the first, and so far only, plant in the United States approved by the FDA to manufacture influenza vaccine cultured in animal cells. It will produce about 50 million doses of seasonal flu vaccine annually, but it has the capacity to expand in emergencies. The Novartis site was designed to have the capacity to produce 200 million doses of flu vaccine within six months of the declaration of a flu pandemic.
The ability to quickly manufacture large quantities of medicine would allow the response center to meet government orders for vaccines or drugs during an outbreak of infectious disease, such as flu, or even Ebola.
“That’s what the cell culture [technology] is predominantly about,” says Brent MacGregor, Novartis’s president of U.S. vaccines. “We’re able to scale up more quickly in the event of a pandemic than would otherwise be the case with egg production.”
The Holly Springs plant already has experience responding to a global pandemic threat. When H7N9 influenza emerged in China last year, Novartis scientists in North Carolina received information about the flu strain from health officials in China. Novartis then used its cell culture technology to develop a vaccine. That H7N9 work emerged from research funded by a separate federal grant awarded to Novartis, which supported collaboration with the J. Craig Venter Institute in San Diego to use synthetic biology to make new influenza vaccines. The H7N9 vaccine produced by Novartis remains stockpiled, for use if needed, in Holly Springs.
In the event of an emerging infectious disease within the United States, the government would take similar steps to respond to the threat. One or more of the response centers could be tasked with making a drug or vaccine for the disease, Robinson says. Those drugs can come from any number of drug companies, including small biotechs such as Mapp Bio. While the Novartis plant in Holly Springs was built for vaccine production, Robinson says its cell culture manufacturing technology makes it capable of manufacturing biological drugs, like ZMapp.
“It’s a biological, a monoclonal antibody,” Robinson says. “So they could make it here.”

Here is the WSJ op-ed.

http://online.wsj.com/articles/scott-gottlieb-and-tevi-troy-stopping-ebola-before-it-turns-into-a-pandemic-1412376544

The following is an EXCERPT. Only two paragraphs are quoted.

Stopping Ebola Before It Turns Into a Pandemic
It’s clear that this disease can’t be contained in West Africa. The best bet is a crash effort to develop and mass- produce drugs and vaccines.
“… After initial testing to determine a product’s safety and level of activity against Ebola, the most promising therapeutics need to be deployed into the field. We’re only going to learn whether drugs and vaccines work by getting real-world information. Conventional, randomized and double-blind clinical trials are not possible in the throes of an epidemic of a deadly pathogen. Given the urgency of the situation, we’re going to have to tolerate more uncertainty than usual.
There is a strong case for inverting the typical process—by doing the hard work of scaling the manufacture of the most promising drugs and vaccines and stockpiling them even while we figure out which ones are working. It may be too late to start large-scale production only after we’re done with more complete clinical testing. Manufacturing an initial half million doses of a vaccine for first responders, or many millions of doses of a drug, would probably cost less than $50 million per product, on average, depending on the kind of therapeutic. The investment spreads the risk and guards against mass-producing a single product only to find out later it was a dud …”

You first.

LOL.

I just saw an interesting thought on the other site. The deputy may have stepped in the decrepit vomitus on the sidewalk outside the apartment and stopped to wipe off his shoes at some point. Then later, w/o washing his hands, wiped his eyes or nose.

from PFIF

Dallas sheriff’s deputies upset about being ordered inside Ebola patient’s apartment without protective gear

By Kevin Krause kkrause@dallasnews.com
3:58 pm on October 3, 2014
http://thescoopblog.dallasnews.com/2014/10/dallas-sheriffs-deputies-upset-about-being-ordered-inside-ebola-patients-apartment-without-protective-gear.html/

Five Dallas County sheriff’s deputies who were ordered Wednesday to go inside the Dallas apartment where an Ebola patient stayed are now worried about their health.

And the sheriff’s association that represents them is not happy about the department’s lack of preparations and precautions before sending them.

Sgt. Chris Dyer, president of the association, said a lieutenant, sergeant and three deputies went inside the apartment to serve the containment warrant that asked the occupants not to leave. The deputies accompanied the county’s health director, Zachary Thompson, and its medical director, Christopher Perkins, to the apartment, Dyer said.

The deputies were not wearing any protective gear, not even latex gloves, Dyer said.

The sheriff’s department later took their vehicles out of service for quarantine and asked the deputies to remove and bag their uniforms and boots, Dyer said. But the deputies were not given any information about potential health hazards, he said.

“These guys are really upset,” he said. “Their families are really upset.”

Dyer said he asked that they all be sent home. He also asked his department’s second in command for a meeting Friday between the deputies and county health officials to provide information about the Ebola virus and to answer questions.

Dyer said the meeting with Perkins and Thompson went well and that his deputies feel better about their situation. They will take their temperature each morning and night for several days and seek medical treatment if they develop a fever or other symptoms, he said.

Sheriff’s spokeswoman Carmen Castro said: “We are simply taking extra precautions so our deputies have some peace of mind.”

Dyer also went to the Ivy Apartments on Wednesday night but did not go inside. He said he and another deputy stood guard all night to monitor the complex and make sure no one entered or left. There were no incidents, he said.

Dyer said he thought federal health officials should have taken control of the scene immediately. The Centers for Disease Control and Prevention should have contained the entire building, he said.

“That may be overkill, but what’s a little overkill when you’re talking about something as serious as this?” he said.

He said the sheriff’s department did not follow its own procedures about coming into contact with potentially hazardous material.

“We went out there with no protection,” he said. “There was a lot of miscommunication and lack of communication.”

__________________________________________________________
What’s Frieden’s favorite phrase again?

I had been thinking the same thing earlier when it was reported that it was someone who lived at the apartments.

I still wonder about those guys with the pressure washers.

Hopefully, this deputy is OK and has just worked himself into feeling sick, but with Ebola and what we’ve been watching in West Africa, you just never know.

I still think one of the family will likely be infected, if not one of the Healthcare Workers that attended to him.

Ordering them in like that was complete lunacy.

Then to have their cars quarantined and their clothes and shoes bagged after the fact, I would have been a nervous wreck.

There was no excuse for this.

A personal injury lawyer might get a settlement for mental anguish. I’d certainly describe this as mental anguish were I the deputies.

Supposedly the state ordered them to present the quarantine papers in such a way that the family didn’t feel dirty or unclean. That means no protective gear.

PC will kill us.

I am really hoping this guy has a regular puke virus.

You and me both.

http://blogs.msf.org/en/staff/blogs/msf-ebola-blog/we-cannot-do-anything-for-her

God bless these HCWs. I may have nightmares from this by just reading it, but they see this and live this every day. Every. Single. Day.

God, please protect them. Amen.

Geez, I can’t be the only person who watched Erin Burnett... Well maybe I could.. I will tape the replay if there is one...