Posted on 08/26/2011 1:12:38 PM PDT by Swordmaker
Alzheimer's disease - a neurospirochetosis. Analysis of the evidence following Koch's and Hill's criteria.
Judith Miklossy
Correspondence: Judith Miklossy judithmiklossy@bluewin.ch
Journal of Neuroinflammation 2011, 8:90 doi:10.1186/1742-2094-8-90
Published: 4 August 2011
Abstract (provisional)
It is established that chronic spirochetal infection can cause slowly progressive dementia, brain atrophy and amyloid deposition in late neurosyphilis. Recently it has been suggested that various types of spirochetes, in an analogous way to Treponema pallidum, could cause dementia and may be involved in the pathogenesis of Alzheimer's disease (AD). Here, we review all data available in the literature on the detection of spirochetes in AD and critically analyze the association and causal relationship between spirochetes and AD following established criteria of Koch and Hill. The results show a statistically significant association between spirochetes and AD (P = 1.5 x 10-17, OR = 20, 95% CI = 8-60, N = 247). When neutral techniques recognizing all types of spirochetes were used, or the highly prevalent periodontal pathogen Treponemas were analyzed, spirochetes were observed in the brain in more than 90% of AD cases. Borrelia burgdorferi was detected in the brain in 25.3% of AD cases analyzed and was 13 times more frequent in AD compared to controls. Periodontal pathogen Treponemas (T. pectinovorum, T. amylovorum, T. lecithinolyticum, T. maltophilum, T. medium, T. socranskii) and Borrelia burgdorferi were detected using species specific PCR and antibodies. Importantly, co-infection with several spirochetes occurs in AD. The pathological and biological hallmarks of AD were reproduced in vitro. The analysis of reviewed data following Koch's and Hill's postulates shows a probable causal relationship between neurospirochetosis and AD. Persisting inflammation and amyloid deposition initiated and sustained by chronic spirochetal infection form together with the various hypotheses suggested to play a role in the pathogenesis of AD a comprehensive entity. As suggested by Hill, once the probability of a causal relationship is established prompt action is needed. Support and attention should be given to this field of AD research. Spirochetal infection occurs years or decades before the manifestation of dementia. As adequate antibiotic and anti-inflammatory therapies are available, as in syphilis, one might prevent and eradicate dementia.
The complete article is available as a provisional PDF. The fully formatted PDF and HTML versions are in production.
This is proof of an hypothesis that we have been pursuing in the dental office I manage and several other dental offices we are associated with. We started noticing that in very elderly patients who were alert, healthy, and did not have any chronic diseases of the heart, diabetes, or mental incapacity that their oral health was also exceedingly good. They also had something completely missing in their mouths. They had no oral spirochetes at all! There was a 100% correlation! Other dentists also were observing this fact. Oral spirochetes were observed in 85-90% of the population but about 10% of the population seems to naturally immune to them and in fact show none at all in their mouths.
One exception to this observation was the edentulous... those without teeth at all. Those who had had all teeth removed! They also were in excellent mental health at an old age, had far less chronic heart disease, and far less likelihood of adult onset diabetes... IF their teeth had been removed at an early age. Strange. Hmmmm.
Oral spirochetes are, we have been observing, associated very strongly with patients who have Alzheimer's Disease, age related dementia, chronic heart disease, and Type 2 Adult onset Diabetes, all diseases associated with plaques. This is the first peer reviewed paper that proves that oral spirochetes, the particular bacteria that we have been seeing under our phase contrast microscope, ARE indeed the cause of Alzheimer's disease.
The same researcher, Dr. Judith Miklossy, who is the president of the Alzheimer's Prevention Association of Europe, issued another peer reviewed paper in 2008, in which she reported that examination of the Islets of Langerhans in patients with Type 2 Diabetes were also rife with oral spirochetes—also further confirming our hypothesis—and mentioned in her 2008 paper that they should be investigated as a possible causal infection for diabetes along with other bacteria she noted.
Spirochetes are bad actors... they are the bacteria that cause syphisis, Yaws, Enug, Lyme disease, and a host of other very nasty diseases. The tertiary form of Syphilis the same dementia and is indistinguishable from Alzheimer's. Lyme disease can do the same dementia.
Oral Spirochete movie from Implant Dr DM at our office.
Another Spirochete movie from our office on youtube.
We have seen a spirochete invade a Leukocyte (white blood cell) and kill it, then leave the dead Leukocyte and go on its way, in one of these movies! We have put up movies on YouTube where the doctor has mentioned the futility using of toothpaste and Youtube, being a part of Google has PULLED them every time! So we don't mention it, anymore... Advertising is king.
In our office, as part of our investigation of the linkage of oral spirochetes to these chronic diseases, our investigation has found that there is an historical progression of the advance of the spread of these chronic diseases in the population associated with the usage of toothpaste. It's a trailing indicator of about 20 years or so, because these diseases take about 20 years to actually appear after the bugs develop in the mouth and migrate into the blood vessels through bleeding gums. However, in the 1910s and 1920s the United States pioneered the use of sweetened pumice in the form of toothpaste to clean teeth, replacing the tooth powder that had been almost universally used prior to then. Sweetened pumice toothpaste has essentially no antibacterial effect even today, no matter what is claimed! Pumice is even harder than the enamel of the tooth surface. It did clean the teeth... but it did not kill bacteria. As a result, 20-30 years down the road, we can see an upsurge in the chronic heart disease, type 2 diabetes, and Alzheimer's start to grow in the populations that adopt toothpaste teeth cleaning... and it's consistent as toothpaste oral hygiene spread from America to Europe to Asia, Latin America, and else where in the world, replacing the former usage of Toothpowder.
You may be asking yourselves what was the Tooth Powder our ancestors used that was supplanted by toothpaste. Some of you may already know. It was essentially ordinary Baking Soda with a little bit of common table salt. The table salt is unnecessary! Baking Soda has a FIVE SECOND kill time on bacteria! It's like dumping a load of poisonous rocks on the bug's heads! It is a mild abrasive that will also clean your teeth and leave your mouth smelling far fresher than toothpaste will! It's CHEAP! You probably have a box in your kitchen! Brush your teeth with Arm and Hammer Baking Soda and floss it down into the gums—the nasty bugs LOVE to stay down in the gingeva. If you have bleeding gums, you have a superhighway for them to enter your blood stream! We have started giving each of our patients an 8oz. box of Arm & Hammer Baking Soda (we buy them for 47¢ each at WalMart by the case. You can buy it by the bag for a lot less per pound) instead of the free toothpaste we used to give.
The protocol is to take a heaping teaspoon of Baking Soda—I do it when I am in the shower—and load your toothbrush with the Soda. Then holding the toothbrush at a 45º angle to the tooth, brush into the gums, working the baking soda into the gums. Use all of the Baking soda and hit all off the gums line. Brush your tongue and the back of your tongue with a tongue brush. Leave the residue. Do not rinse. You will get to like the taste.
The second part of the protocol (this is not so palatable... but you can do it) is once or twice a week take a cap full of Clorox™ brand BLUE CAP bleach—do not use an off brand as we do not know the purity of any other brand—and put it in a glass. Add TWENTY caps fulls of water to make a 20 to 1 dilute mixture of water to bleach... and swish that around in your mouth like mouthwash. It is merely very strong "swimming pool water", called Dakin's Solution, but it will KILL any remaining bacteria in your mouth. It is also the only known substance that will dissolve plaque! Don't worry if you swallow any of it. It will convert to ordinary table salt in your stomach!
If you follow this protocol, you will kill the bacteria that live in your mouth and hopefully prevent any future infection that may cause Alzheimer's, Heart Disease, and adult onset Type 2 Diabetes. We do NOT yet know the life cycle of the Spirochetes... we think they have to reproduce in the mouth... but we are not certain. Dr Miklossy, and other scientists looking at this, hypothesizes the plaques in the brain, Islets of Langerhans, and in the arteries and blood vessels are the left over bodies of dead, twisted entertwined spirochetes... mixed with who knows what... and no one knows if the body can clean up the mess of twenty to thirty years of that build up... but we gotta start somewhere. Cleaning up the source in the mouth seems like a good place!
You can STILL brush your teeth with toothpaste if you like... the Fluoride is still a good idea... but don't be fooled: Even the Arm & Hammer Baking Soda Tooth Paste doesn't have enough baking soda in it to make a difference... Alcohol based mouthwashes don't do it, either.
Are they killed by antibiotics?
bumpety bump
OK. Besides your sage advice on oral hygiene, am I to extract from this that spirochetes correlates with venereal syphilis, correlates with oral sex, correlates with Alzheimer’s?
A medical researcher has just published a peer-reviewed paper in the Journal of NeuroInflamation which proves the hypothesis that the Dental office I manage has been working and researching for five years along with several others around the country.
Essentially, this researcher has found the causal link that shows what we have been telling our patients is true:
We think that in addition to Alzheimer's Disease, several other plaque related diseases, Chronic Artery Disease and Heart Disease, and Adult Onset Type 2 Diabetes, are also caused by Oral Spriochetes invading the body over long term exposure.
The full peer-reviewed paper is available at the link. It is heavy reading but well worth the time.
I am providing you with the prevention protocol we have been giving to our patients for the past five years in hopes it will save both your mind and your life.
Swordmaker
I was wondering if the blue cap bleach is a specific brand or is it Clorox bleach with a blue cap on the bottle?
No, Oral sex has nothing to do with it. You can get Oral Spirochetes by just living in the world. Eating anything... kissing... talking... they are everywhere. Some people, about 10% of the population, are naturally immune to them. Why? We haven't a clue. But 90% of our patients have naturally occurring oral spirochetes in their mouths. So long as they keep their gums healthy, they shouldn't be too much of a problem. The gums are a natural seal that keeps the only place the skeleton sticks through the skin... the teeth. That's why the edentulous who lost their teeth early are also healthier... no break in the skin means no access!
Scary ping. I wonder if this is directly related to the other thread, a drink a day keeps alzheimer’s away? Maybe the daily drink helps kill the little buggers.
Interesting. Thanks.
OK, perhaps I’m not doomed after all...
Do you do the baking soda daily? Also, do you floss before or after the baking soda? I’ve always liked baking soda as a toothpaste but my dentist discouraged it as it is a bit abrasive. Very interesting.
Listerine kills them.
“First, if you look at what kills spirochetes making plaque in your mouth, you will notice that the key ingredients include four essential oils present in products like Listerine.
Further, we have been working with biological chemists who are extracting a wide range of natural chemicals from various botanicals. Some grow bacteria and others kill bacteria but hurt human membranes. Others kill bacteria and are profoundly safe.”
From here...
http://www.publichealthalert.org/Articles/jamesschaller/18_reasons_lyme_treatments_fail.htm
We use a very expensive Nikon Phase Contrast Microscope... they are hard to see otherwise.
And yes, they can be killed by antibiotics... which ones I am not sure. The article says that Alzheimer's patients are affected by antibiotics "at first" but then continue on the course of the disease. That may be because it is a long term 20-30 year problem and it is too late by the time the dementia starts showing and the damage is done. Now that we KNOW the cause, earlier treatment may be effective, before the plaques have time to build up and cause the physiological changes to the brain.
I can’t use baking soda either. I have veneers. I was told NOT to use baking soda or salt because it scratches them.
Would you please check into the Listerine (because I can’t use baking soda) which kind works best and clarify about the “blue cap” bleach?
I’m 50 with Alzheimers in my family.
It's the Clorox™ brand-name with a blue cap on the bottle. Clorox uses the caps to indicate specific sub-branding. The Blue Cap indicate pure bleach without any additives. No scents, etc. You really don't want any other chemicals added. We strongly don't recommend any other brand because we DON'T know what they have in them. The Clorox™ brand has stuck with this designation for years and is reliably chemically pure.
Well, Alcohol is antibacterial, but... it's not as effective, nor does it really get all of them. But something is better than nothing, I guess. I haven't heard of flossing with whiskey...
Thank you for the information and posting, Swordmaker. I have used peroxide with baking soda a few times a week. However, I will also add the newer recommendations!
bump alzheimers and teeth/plaque
Oh, If I recall the full article correctly, she did find a correlation with the spirochetes that cause syphilis in AD patients, but it was only 69% while the Oral spirochetes were 95%. It's hard to tell how much was what in those cases... The symptoms of both are almost identical in the tertiary stages...
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