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Alzheimer's disease - a neurospirochetosis.
The Journal of NeuroInflamation ^ | August 4, 2011 | By Judith Miklossy, MD

Posted on 08/26/2011 1:12:38 PM PDT by Swordmaker

Alzheimer's disease - a neurospirochetosis. Analysis of the evidence following Koch's and Hill's criteria.

Judith Miklossy
Correspondence: Judith Miklossy judithmiklossy@bluewin.ch

Journal of Neuroinflammation 2011, 8:90 doi:10.1186/1742-2094-8-90

Published: 4 August 2011
Abstract (provisional)

It is established that chronic spirochetal infection can cause slowly progressive dementia, brain atrophy and amyloid deposition in late neurosyphilis. Recently it has been suggested that various types of spirochetes, in an analogous way to Treponema pallidum, could cause dementia and may be involved in the pathogenesis of Alzheimer's disease (AD). Here, we review all data available in the literature on the detection of spirochetes in AD and critically analyze the association and causal relationship between spirochetes and AD following established criteria of Koch and Hill. The results show a statistically significant association between spirochetes and AD (P = 1.5 x 10-17, OR = 20, 95% CI = 8-60, N = 247). When neutral techniques recognizing all types of spirochetes were used, or the highly prevalent periodontal pathogen Treponemas were analyzed, spirochetes were observed in the brain in more than 90% of AD cases. Borrelia burgdorferi was detected in the brain in 25.3% of AD cases analyzed and was 13 times more frequent in AD compared to controls. Periodontal pathogen Treponemas (T. pectinovorum, T. amylovorum, T. lecithinolyticum, T. maltophilum, T. medium, T. socranskii) and Borrelia burgdorferi were detected using species specific PCR and antibodies. Importantly, co-infection with several spirochetes occurs in AD. The pathological and biological hallmarks of AD were reproduced in vitro. The analysis of reviewed data following Koch's and Hill's postulates shows a probable causal relationship between neurospirochetosis and AD. Persisting inflammation and amyloid deposition initiated and sustained by chronic spirochetal infection form together with the various hypotheses suggested to play a role in the pathogenesis of AD a comprehensive entity. As suggested by Hill, once the probability of a causal relationship is established prompt action is needed. Support and attention should be given to this field of AD research. Spirochetal infection occurs years or decades before the manifestation of dementia. As adequate antibiotic and anti-inflammatory therapies are available, as in syphilis, one might prevent and eradicate dementia.

The complete article is available as a provisional PDF. The fully formatted PDF and HTML versions are in production.


TOPICS: Science
KEYWORDS: alzheimers; alzheimersdisease; bakingsoda; gumdisease; neurospirochetosis; sciencediscovery; spirochetalinfection; spirochetes
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To: Quix

Thanks for the ping!

Sounds like it might work.


181 posted on 08/29/2011 7:23:52 AM PDT by Califreak (Degenerate the faithful with that crazy casbah sound)
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To: Swordmaker; FredZarguna; Quix

Wow, Thank You all for the valuable information!


182 posted on 08/29/2011 7:58:59 AM PDT by marbren (I do not know but, Thank God, God knows)
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To: Swordmaker; Bon mots

Thanks Bon Mots,

I know what dental problems can entail, for sure.

Swordmaker, evidently you are saying I don’t even need to do the mouthwash with your solution thing once?

No holes in my gums. Gums shrank and shrank over a year and a half after extraction. Now have final hard liner . . .

I use the glue pads to avoid the yucky stuff in the normal adhesive. Works well enough. No longer painful. Hate the mess and bother. Without the adhesive pads—workable but loose a bit. Anyway—better than some options in life!

Still keep praying for God to replace with real teeth. Known of it happening. But then I’d have to floss again! LOL.

GREATLY APPRECIATE THIS THREAD AND YOUR EXCELLENT INFO.

May God bless you 100 fold.

BTW, Stockton doesn’t appear to fare well, IIRC, on John Moore’s Navy & Stan Deyo’s Hopi maps.

Let me check.

UNDERWATER ALRIGHT.

Your elevation doesn’t look too high there.

Sadly, you might pray about relocating . . . soonish . . . I don’t think anyone has a good timeline.

Though with war festivities supposedly being alighted between now and the end of the year . . . the pace could pick up across the board.


183 posted on 08/29/2011 8:17:27 AM PDT by Quix (Times are a changin' INSURE you have believed in your heart & confessed Jesus as Lord Come NtheFlesh)
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To: Califreak; Swordmaker

INDEED.

Praise God for Swordmaker’s caring and faithfulness.


184 posted on 08/29/2011 8:18:26 AM PDT by Quix (Times are a changin' INSURE you have believed in your heart & confessed Jesus as Lord Come NtheFlesh)
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To: Quix; Swordmaker

thanks for this! I will read it more thoroughly later


185 posted on 08/29/2011 11:15:21 AM PDT by holly go-rightly
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To: Swordmaker

Thank you very much for sharing this. I had nursing instructors that were trained around WWII. They were some old broads! I learned from them the importance of good oral hygiene and the potential for entry of pathogens via gums. It’s pretty simple logic- if skin is the largest organ and the body’s first line of defense, pathogens can enter through a cut and migrate. Same thing with the gums if their integrity/ health is compromised. Seems rather common sense. It isn’t a stretch to believe that the spirochetes migrate from the mouth. My husband and I switched to baking soda years ago. I use 1/2 strength peroxide a few times a week. I need to be a little more diligent, and I’ll be picking up some Chlorox. Again, thanks for sharing this. I wonder how long before the ADA has a fit over this though. Who makes money if we can cure ourselves?


186 posted on 08/29/2011 1:07:06 PM PDT by pops88 (Geek chick over 40)
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To: holly go-rightly; Swordmaker

I just dropped the articles and a key post or 2 off by my great Dentist here. He thought it looked good.

Thanks for your kind reply.

Swordmaker—where would my local Dentist go to be trained in the latest procedure and materials?


187 posted on 08/29/2011 2:05:51 PM PDT by Quix (Times are a changin' INSURE you have believed in your heart & confessed Jesus as Lord Come NtheFlesh)
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To: Quix

>> “Your elevation doesn’t look too high there.” <<

.
LOL! Most of Stockton is between 12 feet and 20 feet elevation. Stockton is the original “Mudville” of the poem.


188 posted on 08/29/2011 5:24:08 PM PDT by editor-surveyor (Sarah Palin - 2012 !)
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To: Swordmaker

Wouldn’t bleach then dissolve the gums etc.?


189 posted on 08/29/2011 5:39:38 PM PDT by rwfromkansas ("Carve your name on hearts, not marble." - C.H. Spurgeon)
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To: rwfromkansas
Wouldn’t bleach then dissolve the gums etc.?

It would if you left it long enough and it was in a stronger concentration. At 20-1, not so much. We are talking what is basically strong swimming pool water here. Sodium Hypochlorite— NaClO—Lose the oxygen atom and you have ordinary table salt.

190 posted on 08/29/2011 10:30:17 PM PDT by Swordmaker (This tag line is a Microsoft product "insult" free zone.)
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To: Swordmaker

wow, thanks. not much to do for a potential big effect.


191 posted on 08/30/2011 1:26:24 AM PDT by cycjec
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To: Swordmaker

wow, thanks. not much to do for a potential big effect.


192 posted on 08/30/2011 1:26:34 AM PDT by cycjec
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To: cycjec
wow, thanks. not much to do for a potential big effect.

Just one more thing. The Dakin's bleach solution has to be made fresh every day you use it... It doesn't keep. It degrades to salt water within hours. Good health!

193 posted on 08/30/2011 3:10:06 AM PDT by Swordmaker (This tag line is a Microsoft product "insult" free zone.)
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To: Swordmaker

Later


194 posted on 08/30/2011 4:01:28 AM PDT by I_be_tc
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To: Swordmaker
Grape Fruit Seed Extract will do the same thing, no need to be using bleach in your mouth ...


195 posted on 08/30/2011 4:04:43 AM PDT by Scythian
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To: Scythian
Grape Fruit Seed Extract will do the same thing, no need to be using bleach in your mouth ...

No, it won't. Sorry. I assure you these things have been thoroughly researched.

Follow the science, Scythian. Exhaustive chemistry done on Grapefruit seed extract found that the only antimicrobial (very weak) effect any commercial product had was due to contaminants introduced accidentally or deliberately during manufacture! My money is on "deliberately." The components from ground up Grapefruit seeds could not possibly chemically combine to MAKE the active ingredient, benzalkonium chloride, a synthetic antimicrobial; it had to have been added!

Also, It will not dissolve plaque! The ONLY known substance that will do that safely is Sodium Hypochlorite, bleach.

196 posted on 08/30/2011 11:46:12 AM PDT by Swordmaker (This tag line is a Microsoft product "insult" free zone.)
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To: Swordmaker

I’ve read all that stuff on GSE, it’s not true, but I can tell we won’t agree. If you are talking about Coronary Plaque then Magnesium, l-arginine are the ticket, however, there are some warnings on l-largine if you’ve already had a heart attack. COQ10 is the antibiotic of the heart, I take it every day ...


197 posted on 08/30/2011 12:20:15 PM PDT by Scythian
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To: Swordmaker

Okay, I’m willing to try this protocol, I have had lyme many times in my life and suffer inflammation issues. The only question I have is why not spit the Baking Soda out at the end, why swallow it? It is incredibly alkalizing and could cause a person to become to alkaline. Is it okay if I spit it out?


198 posted on 08/30/2011 12:41:19 PM PDT by Scythian
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To: Scythian
I’ve read all that stuff on GSE, it’s not true, but I can tell we won’t agree. If you are talking about Coronary Plaque then Magnesium, l-arginine are the ticket, however, there are some warnings on l-largine if you’ve already had a heart attack. COQ10 is the antibiotic of the heart, I take it every day ...

It IS true... the studies have been peer reviewed. I can tell you that it has no affect on its own to kill oral bacteria. It simply does not. We can take a sample see the bacteria active... use the GSE and take another sample and see NO DIFFERENCE. QED. It does not work.

You have no scientific proof for your claims. I do, for mine. I will go with the science, not the wishful thinking. Perhaps COQ10 may kill spirochetes, but until they show me that it does, and they have not even yet accepted that plaques are the CAUSE of the plaques, which this study is finally starting to show, they are not even looking at a bacteriological causation!

199 posted on 08/30/2011 2:06:58 PM PDT by Swordmaker (This tag line is a Microsoft product "insult" free zone.)
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To: Scythian
The only question I have is why not spit the Baking Soda out at the end, why swallow it? It is incredibly alkalizing and could cause a person to become to alkaline. Is it okay if I spit it out?

You DO spit it out... just don't RINSE it out. Leave it to work on the gums and kill bugs. It will give you sweeter smelling breath, too.

Swallowing it will not harm you. It will be neutralized by your stomach acid. And if you have an acidic stomach, or gassy tummy... it will settle it down.

200 posted on 08/30/2011 2:14:22 PM PDT by Swordmaker (This tag line is a Microsoft product "insult" free zone.)
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