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Test shows once-a-day malaria treatment highly effective
AFP ^ | Apr 22, 2010 | Unknown

Posted on 04/23/2010 4:37:36 AM PDT by decimon

A new combination treatment for malaria is as effective as the "gold standard" therapy for the disease, but only needs to be taken once a day rather than twice, The Lancet reported on Friday.

The new treatment, combining pyronaridine and artesunate, was tested at seven sites in Africa and three in Southeast Asia alongside the standard drugs, artemether and lumefantrine.

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Its success against malarial parasites was first found centuries ago in ancient China but was rediscovered by Chinese medical researchers in the early 1970s.

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(Excerpt) Read more at news.yahoo.com ...


TOPICS: Health/Medicine; Science
KEYWORDS: malaria; microbiology
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1 posted on 04/23/2010 4:37:37 AM PDT by decimon
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To: neverdem; DvdMom; grey_whiskers

Wormwood ping.


2 posted on 04/23/2010 4:38:23 AM PDT by decimon
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To: decimon

Treatments of DDT are effective, as well.


3 posted on 04/23/2010 4:40:20 AM PDT by AF_Blue ("Are you guys ready? Let's roll!" - Todd Beamer)
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To: AF_Blue

It’s a shame we can’t just stamp out this disease with simple, cheap, harmless application of common pesticides. We could save a lot of money and eliminate a lot of needless suffering and death.


4 posted on 04/23/2010 4:42:03 AM PDT by Haiku Guy (Gov. Chris Christie (R) won the NJ-6 held by Rep. Frank Pallone (D) by a 15.5% margin!)
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To: decimon

DDT is soo much better. It prevents malaria instead of treating the symptoms! But, the environment is so much more important than-people! /s


5 posted on 04/23/2010 4:51:24 AM PDT by Lil Flower ("Without Love, deeds, even the most brilliant, count as nothing." St. Therese of Lisieux)
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To: Lil Flower

“But, the environment is so much more important than-people! /s”

Sadly, DDT doesn’t hurt the environment or people.

I’m convinced that DDT was banned to address the UNs highest priority, over-population.


6 posted on 04/23/2010 5:24:05 AM PDT by driftdiver (I could eat it raw, but why do that when I have a fire.)
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To: Jemian

ping


7 posted on 04/23/2010 6:17:20 AM PDT by JRandomFreeper (Gone Galt)
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To: JRandomFreeper

Thanks for the ping. One of the best things about both artesunate and artemeter is that there are relatively few side-effects. FWIW, when I have taken them, I have noticed none and in all but about two bouts of malaria, I’ve been able to function normally within hours.


8 posted on 04/23/2010 6:32:20 AM PDT by Jemian ( Mr. President, Tear down this Law!)
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To: Jemian

Glad to see you’ve responded well to the treatments.

The article indicates these treatments are curative, i.e., ridding blood of the parasites. Is that your experience?


9 posted on 04/23/2010 6:50:11 AM PDT by decimon
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To: decimon

They are highly curative for the parasite in the bloodstream. It is my understanding that it doesn’t affect the parasite lying dormant in the liver.


10 posted on 04/23/2010 7:14:44 AM PDT by Jemian ( Mr. President, Tear down this Law!)
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To: Jemian
They are highly curative for the parasite in the bloodstream. It is my understanding that it doesn’t affect the parasite lying dormant in the liver.

Thanks.

I guess that means it can recur.

11 posted on 04/23/2010 8:01:29 AM PDT by decimon
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To: Jemian

I don’t recall what the heck I took when I came down with a raging bout when I was working in eastern Africa...but I have not had any residual problems. I do recall staggering out of the clinic at the mine with a bag full of meds, (and a new mosquito net!) and whatever the prescribed, I was over it in about 15-days. Seems I was still taking meds for about a month.

Not fun at all!


12 posted on 04/23/2010 8:07:17 AM PDT by Cuttnhorse ("It is terrible to contemplete how few politicians are hanged." - G.K. Chesterton, 1921)
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To: decimon

Yes, it can reoccur. In fact, if I get a major cold, flu, or have surgery, I expect a reoccurrance of malaria about 10 - 14 days after.

A person can take primaquin (unless they’re of African or medaterranean descent) after leaving a malaria area for erradication from the liver. I don’t bother with it because I’m going right back in a short time. I also don’t take prophalaxis because those meds over a long time period are poison and will destroy a liver.

Disclaimer: I am not a medical person. Each individual has to make their own decision based on your own research.


13 posted on 04/23/2010 8:53:19 AM PDT by Jemian ( Mr. President, Tear down this Law!)
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To: Cuttnhorse

Some of the treatment can and must continue long past symptoms have disappeared. My guess is that you had quinnine. IMO, it is the medicine from hell (until I took Larium. More on that later). It left me staggering, dizzy, hearing things, vision disoriented, etc. I had to take a medicine a half hour prior to taking quinnine in order to keep it down! It was no fun. No fun at all. Not any.

But then, I took mefloquin, aka Larium. It worked. But then a week later, it threw my BP sky-rocketing. I showed heart-attack symptoms. Further, for the next six months I spiraled downward into the worst depression I have ever experienced. Worthless feelings, almost suicidal, hopelessness, despair. The only reason I made it through that experience was God’s grace and knowing that my feelings were not based on reality but were chemically induced. I will NEVER take that med again.


14 posted on 04/23/2010 8:59:36 AM PDT by Jemian ( Mr. President, Tear down this Law!)
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To: Jemian; Cuttnhorse

Thanks again. Interesting.

Don’t know what else to say but to wish you and Cuttnhorse well.


15 posted on 04/23/2010 10:35:23 AM PDT by decimon
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To: driftdiver
I’m convinced that DDT was banned to address the UNs highest priority, over-population.

Bingo.

16 posted on 04/23/2010 10:36:36 AM PDT by Lurker (The avalanche has begun. The pebbles no longer have a vote.)
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To: decimon

Thank you. It doesn’t often cause me problems as bad as a cold. Rarely does it take long to recover.


17 posted on 04/23/2010 10:44:15 AM PDT by Jemian ( Mr. President, Tear down this Law!)
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To: decimon
Its success against malarial parasites

I don't know if there's any correlation but I regularly eat pickles and have never contracted malaria in my life.......I've never been divorced either.

18 posted on 04/23/2010 10:47:43 AM PDT by Hot Tabasco (Peanut butter was just peanut butter until I found Free Republic.........)
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To: decimon; Mother Abigail; EBH; vetvetdoug; Smokin' Joe; Global2010; Battle Axe; null and void; ...
bump & a micro ping

Efficacy and safety of a fixed-dose oral combination of pyronaridine-artesunate compared with artemether-lumefantrine in children and adults with uncomplicated Plasmodium falciparum malaria: a randomised non-inferiority trial

Deadly New Fungus Emerging in Oregon Expected to Spread

19 posted on 04/25/2010 3:18:05 PM PDT by neverdem (Xin loi minh oi)
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To: decimon; neverdem; DvdMom; grey_whiskers

My dad was station in the South Pacific during WWII. There is a tree/shrub that grow on the island he was stationed on that repells the misquito that spreads the disease.

They were the only soldiers that did not have to take preventative measures for the disease.

For years he has tried to spread the word. Contact individuals who might be interested in research or transplanting the tree to areas that would protect populations.

No success so far. Any one with any ideas of who to contact to give information, let me know.


20 posted on 04/25/2010 6:38:57 PM PDT by hoosiermama (ONLY DEAD FISH GO WITH THE FLOW.......I am swimming with Sarahcudah! Sarah has read the tealeaves.)
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