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Keyword: trpa1

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  • Tarantula Venom Could Lead to New Effective Painkillers

    04/27/2014 8:10:28 PM PDT · by neverdem · 74 replies
    Sci-News.com ^ | Feb 17, 2014 | NA
    Using an innovative screening method, a team of scientists from Australia and the United States has discovered a peptide in the venom of the Peruvian green velvet tarantula (Thrixopelma pruriens) that blunts activity in pain-transmitting neurons.Tarantula. Image credit: Michael Gäbler / CC BY 3.0. The novel method, named toxineering, has the potential to search millions of different spider toxins for safe pain-killing drugs and therapies.Dr Michael Nitabach from Yale School of Medicine and his colleagues screened toxins from a variety of tarantula species to find one that blocked TRPA1, an ion channel on the surface of pain-sensing neurons that is...