Free Republic

A new Covid variant that is behind a resurgence in hospital admissions may be more deadly than previously thought, research suggests. BA.2.86 — or 'Pirola' — is a mutation on the Omicron BA.2 subvariant and is the ancestor of the currently dominant JN.1, which is responsible for more than three in five Covid cases as of January 6. Both strains have around 60 more spike protein mutations than the original coronavirus and over 30 more than other Omicron variants such as BA.2 and XBB.1.5.

TOPLINE Pirola, or BA.2.86, is the third most prevalent Covid strain in the U.S., and although there may be concerns the new monovalent vaccines—which protect against the XBB lineage that Pirola isn’t a part of—don’t offer protection against Pirola and its subvariants, drugmakers and the CDC are sure the vaccines offer defense. Pirola made up 8.8% of cases as of November 25, almost triple the number of cases the variant made up during the previous two-week period ending on November 11, when Pirola wasn’t even one of the top five most prevalent variants, according to data from the Centers for...

As COVID-19 cases continue to rise nationwide, a new variant dubbed “Pirola” has experts worried. Also referred to as BA.2.86, Pirola is a highly mutated variant of the Omicron strain of the coronavirus, which emerged in 2021 and led to a frightful spike in COVID-19 cases and deaths. “When Omicron hit in the winter of 2021, there was a huge rise in COVID-19 cases because it was so different from the Delta variant, and it evaded immunity from both natural infection and vaccination,” infectious disease specialist Dr. Scott Roberts said in a Yale Medicine bulletin. The bulletin states that “there...

A highly mutated new variant of the virus that causes Covid-19 has countries on alert as scientists scramble to understand how far it has spread and how well our immunity will defend against it. The new variant, called BA.2.86 and nicknamed Pirola by variant hunters on social media, has more than 30 amino acid changes to its spike protein compared with its next closest ancestor, the BA.2 subvariant of Omicron, according to Dr. Jesse Bloom, who studies viral evolution at the Fred Hutchinson Cancer Center in Seattle. “This makes it an evolutionary jump comparable in size to that which originally...