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The viruses are out there, and they are out to get us
The Canberra Times | 28 February 2003

Posted on 02/27/2003 6:26:28 PM PST by Wallaby

Not for commercial use. Solely to be used for the educational purposes of research and open discussion.

The viruses are out there, and they are out to get us
It is possible that the Black Death is not dead and that a new 'bird flu' is another potential mass killer

The Canberra Times
Section A; Pg 17
February 27, 2003 Thursday Final Edition


LATE last month an eight-year-old girl from Hong Kong visiting relatives in southern China fell ill with influenza and was admitted to hospital. A week later she died, and since then her father has died of the same flu, while her nine-year-old brother lies gravely ill in an isolation ward in Hong Kong.


It is only when a lethal new virus crosses the species barrier and then starts to pass from one person to another that the alarm bells start to ring. They are ringing now.
The virus is outwardly similar to the A (H5N1) strain, also known as 'bird flu', which killed six of the eighteen people who were infected in the last outbreak in Hong Kong in 1997.

New strains of viral diseases that can kill human beings generally emerge by mutation as they hop back and forth between people and their domesticated animals. This exchange of viruses goes on all the time in farming areas, but it is only when a lethal new virus crosses the species barrier and then starts to pass from one person to another that the alarm bells start to ring. They are ringing now.

'If this virus is transmissible from human to human then it is far more serious,' said a spokesperson for the World Health Organisation in Geneva on February 19.

The 1997 flu virus was stopped by slaughtering the 1.4 million chickens, ducks and geese in Hong Kong, but if the new one is already loose all over southern China that solution will not really work.

Even the normal wave of flu that circles the world every year, slightly changed genetically each time, exacts a serious toll in lives, but once in a while something really lethal comes along. This could be one of those times. The 'Spanish flu' pandemic of 1918 infected between 20 and 40 per cent of the world's population and killed 20 million people in four months, twice as many as died in World War I, and the majority of the victims were young, healthy people who died of complications like bronchitis and pneumonia. If a flu virus like that appeared now, could it do as much damage?

Certainly, the two subsequent flu pandemics, occurring after the development of anti-viral medicines, did not cause the same carnage. The effect of the 1957 'Asian flu' pandemic was greatly reduced by mass vaccination; only one human being in six caught it, and it killed an estimated two million people worldwide. The 1968 'Hong Kong flu' pandemic killed only a million people and, as in 1957, most of the victims were elderly.

However, viruses are not impressed by medical technology. Despite the far higher standards of sanitation and medical care in the developed world, influenza death rates there have not been significantly lower than in poorer countries. Viral diseases mutate fast, antibiotics are no use against them, and good hygiene is no protection either. Bacterial diseases like cholera, anthrax and malaria have complex life cycles and mutate only slowly, so they are easy to contain, but if the latest version of 'bird flu' is transmissible between people, we could be looking at millions of deaths over the next year. Nor is that the worst that could happen.

The true nature of the 'Black Death' was long a mystery, but early in the 20th century, after doctors had found and described bubonic plague in India, experts jumped to the conclusion that a more virulent form of that disease, endemic in rats and transmitted to humans by their fleas, was the real culprit.

This was a comforting conclusion, because it meant that it was a bacterial disease with a complicated life-cycle, easily contained by hygiene and antibiotics, that would never come back to trouble modern human beings. However, it never actually made sense, because the standard treatment for the Black Death, tried and tested over 300 years, was to quarantine affected families and villages for 40 days. That could not have worked if it were carried by rats, which do not respect quarantines.

So two years ago professors Christopher Duncan and Susan Scott of Liverpool University suggested in their book Biology of Plagues that the Black Death was really an Ebola-like virus, a hemorrhagic fever transmitted directly from person to person. It is frighteningly plausible.

There were actually two Great Pandemics, and the first hit Europe and the Middle East in AD 541. The Roman empire had been relatively unharmed by great plagues, apart from bouts of smallpox in 170 and measles in 250, which killed mostly children and left survivors immune, but the new plague was different. It returned about every 10 years for the next two centuries, and reduced the population of the Mediterranean area by between 30 and 50 per cent. Large parts of the Middle East and North Africa did not recover their pre-540 populations until about 100 years ago.

The plague called the Black Death appeared in Mongolia in the 1320s, and killed two-thirds of China's population between 1330-50. It reached Europe in 1347, and killed between 30 and 40 per cent of the population in the first onslaught. It returned at intervals of about a decade, with gradually diminishing lethality, until it disappeared at the end of the 17th century.

The aching, the bleeding from internal organs, the red blotches on the skin caused by the effusion of blood under the skin, were all typical of Ebola-style fevers. Besides, bubonic plague, unlike the Black Death, did not disappear. There was an outbreak of bubonic plague in Glasgow as recently as the 1890s.

If Duncan and Scott are right, therefore, there is a virus out there somewhere, dormant for the moment while it tries out mutations that might break through the genetic defences that human beings evolved to defeat it last time, which could kill a significant portion of the human race in a year. The Black Death is not dead, it is only sleeping. In the meantime, the 'bird flu' may be coming.


TOPICS: Miscellaneous; News/Current Events
KEYWORDS: antonineplague; blackdeath; byzantineempire; godsgravesglyphs; helixmakemineadouble; influenza; justinianplague; justiniansplague; michaeldobbs; naturalantibioticag; plague; plagueofathens; plagueofjustinian; romanempire; silvernaturescure; viruses; yersiniapestis

1 posted on 02/27/2003 6:26:28 PM PST by Wallaby
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To: *all
Large parts of the Middle East and North Africa did not recover their pre-540 populations until about 100 years ago.
2 posted on 02/27/2003 6:35:01 PM PST by Wallaby
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To: Wallaby
More good news.:)
3 posted on 02/27/2003 6:38:35 PM PST by independentmind
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To: Wallaby
the standard treatment for the Black Death, tried and tested over 300 years

Er, the fact the Black Death was able to kill off such a large fraction of the population shows that the techniques used at the time were tried, tested, and failed the test.

4 posted on 02/27/2003 6:44:29 PM PST by steve-b
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To: Wallaby
BTTT
5 posted on 02/27/2003 6:52:55 PM PST by Salvation (†With God all things are possible.†)
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To: Wallaby
"There were actually two Great Pandemics, and the first hit Europe and the Middle East in AD 541."

"Large parts of the Middle East and North Africa did not recover their pre-540 populations until about 100 years ago."

Trees worldwide recorded a catastrophe in 540AD +-4.0 years. The whole world went into a Dark Age beginning about this time. Some believe a comet swarm struck the earth.

6 posted on 02/27/2003 6:57:45 PM PST by blam
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To: blam
538 AD was the "event". It precipitated a serious cooling and drying of the Earth which then favored an environment in tune with the needs of rats.

The plague of Justinian hit in 541.

Barbara Tuchman noted that the black death of the late 1300s had a high death rate in the Mediterranean but by the time it reached Norway the death rate had dropped to 10% of the population. Modern analysis has revealed that a large percentage of Northwestern European populations have an hereditary defense against bubonic plague, AIDS, typhoid and cholera.

It's good to be a survivor, eh?!

7 posted on 02/27/2003 7:26:28 PM PST by muawiyah
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To: Wallaby
Oh, thank you. I was just sitting down to a magnificent steak dinner with garlic potatoes and a salad of spring greens tossed in a sesame mayo, when I noticed a flea crawl out of my salad bowl and onto my dinner plate. The flea walked right on my potatoes and steak, undoubtedly spreading bubonic plague every inch of the way. So I put my whole dinner in one of those steam autoclave sterilizing things at the local hospital, but I'm afraid dinner wasn't too palatable after that... overcooked, y'know, especially the salad. Unfortunately, the flea was not overcooked or even fazed by this experience and flew away. I'm starved but I can't even cut the steak now and have to go to bed hungry.

Other than that, nice to hear from you :-) :-)

8 posted on 02/27/2003 7:34:31 PM PST by T'wit
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To: muawiyah
"The plague of Justinian hit in 541."

Yup. the whole world took a 'hit' at about that time. I was reading just last night about the hit taken by the Mayans. I guess us Northwestern Europeans took our losses in 541AD, only those with some immunity survived...and they are our ancestors.

9 posted on 02/27/2003 7:52:33 PM PST by blam
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To: T'wit
The flea was harmless but that steak'll kill you! ;-)

Good bumping into you again, old friend.

10 posted on 02/27/2003 8:20:23 PM PST by Wallaby
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To: Wallaby
A deadly flu bug was recently reported here in the States http://www.freerepublic.com/focus/news/850745/posts
11 posted on 02/27/2003 8:32:45 PM PST by beware of dog
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To: T'wit; Wallaby
I thought I had washed myself of the two of you already - where's that bottle of alcohol?
12 posted on 02/27/2003 8:37:01 PM PST by Senator Pardek
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To: Senator Pardek
.>where's that bottle of alcohol?

T'wit's got it, but there's a flea that crawled into it and drowned.

13 posted on 02/27/2003 8:41:31 PM PST by Wallaby
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To: Wallaby
"The flea was harmless but that steak'll kill you! ;-)"

I just got done with a cycle of doxcycline for a flea bite. It had a large circle around the bite point and the doc gave me the antibotics as a precaution for Lyme disease. Hmmmm

14 posted on 02/27/2003 8:56:43 PM PST by blam
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To: muawiyah
Six hundred and fifty years ago, the Black Death was stalking Europe. It arrived on ships from Asia, carried by fleas that had infected rats on board the ships. Before it burned itself out, the epidemic had killed about a third of the European population.

Today, another plague - AIDS - has ravaged the world. Although it seems very different from the Black Death, there is one eerie similarity. Both the Black Death bacteria, Yersinia pestis, and HIV, the virus that causes AIDS, home in on macrophages, which are scavenger white blood cells of the immune system.

Now, in a provocative report, scientists at the National Cancer Institute in Frederick, Md., say they have found that a genetic mutation that protects against the AIDS virus, by preventing the virus from entering macrophages, emerged in Europe around the time of the Black Death.

And, they have found, this AIDS resistance gene is astonishingly common in people whose ancestors lived in areas of Europe that were ravaged by the Black Death.

The HIV resistance gene destroys a protein, called CCR5, that pokes out of the surface of macrophages, the large white blood cells that can engulf and kill viruses and bacteria.

Scientists have discovered that when HIV infects a person, the virus goes straight to the white blood cells and in particular the macrophages, latches onto CCR5 and another protein, CD4, to hoist itself inside.

It lives there for about a decade, throwing off billions of genetic variants. Eventually it makes a variant that can get into another type of white blood cell, the T cells. Then the infected person's immune system starts to decline, and the terrible symptoms of AIDS appear.

People who inherit two copies of the HIV resistance gene can only be infected with HIV if they happen to come in contact with a virus from someone in the late stages of infection, when the virus can go straight for the T cells.

10 percent of Caucasians have a copy of the gene, which slows the progress of HIV infections by several years, and one percent have two copies, which provides nearly complete immunity to HIV.

The HIV resistance gene is most common among British and other northern European people, and declines in frequency further south.

Thus, it is present in almost 14 percent of Swedes but appears in only about 5 percent of Italians and is absent in Saudi Arabia. It is absent in Africans, American Indians and Asians. The gene emerged in the Caucasian population long after Caucasians split from Asians, which was about 50,000 to 100,000 years ago.

And so, although the bubonic plague began in Asia, the HIV resistance gene is not there.
15 posted on 02/27/2003 9:13:59 PM PST by Neuromancer
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To: Neuromancer
Another thing to note concerning diseases which spread using the rat, or the rat's fleas as a vector is that people in NW Europe, particularly Scandinavia, live in an area with a very high incidence of rats.

Other people do not, e.g. residents of the Arabian peninsula.

The NW European resistance to such diseases should be expected, otherwise there would be no NW Europeans!

16 posted on 02/28/2003 5:34:57 AM PST by muawiyah
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Note: this topic is from 2/27/2003. Thanks Wallaby.

17 posted on 10/24/2015 7:42:41 PM PDT by SunkenCiv (Here's to the day the forensics people scrape what's left of Putin off the ceiling of his limo.)
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