Most Significant Scientific Retraction Ever? ( Alzheimer's Disease)

https://hotair.com/david-strom/2024/06/07/most-significant-scientific-retraction-ever-n3789789 ^ | 6/8/2024 | david strom

[bitt]

It may or may not be the most significant retraction of a scientific paper ever, but it certainly is in the ballpark.

The paper helped create and sustain the theory that amyloid protein buildups caused the symptoms of Alzheimer's Disease and was one of a number of apparently fraudulent papers written by Sylvain Lesné, a professor at the University of Minnesota, Twin Cities.

All the paper's authors agreed to retract, save Lesné, who has been under investigation for manipulating data.

"Authors of a landmark Alzheimer’s disease research paper published in Nature in 2006 have agreed to retract the study in response to allegations of image manipulation. University of Minnesota (UMN) Twin Cities neuroscientist Karen Ashe, the paper’s senior author, acknowledged in a post on the journal discussion site PubPeer that the paper contains doctored images. The study has been cited nearly 2500 times, and would be the most cited paper ever to be retracted, according to Retraction Watch data.

“Although I had no knowledge of any image manipulations in the published paper until it was brought to my attention two years ago,” Ashe wrote on PubPeer, “it is clear that several of the figures in Lesné et al. (2006) have been manipulated … for which I as the senior and corresponding author take ultimate responsibility.”

After initially arguing the paper’s problems could be addressed with a correction, Ashe said in another post last week that all of the authors had agreed to a retraction—with the exception of its first author, UMN neuro-
scientist Sylvain Lesné, a protégé of Ashe’s who was the focus of a 2022 investigation by Science. A Nature spokesperson would not comment on the journal’s plans."

[bobbo666]

There is no consequence. They got their fame and the $$ that brings — time to lift the rug and sweep.

[PGR88]

Science is an abstract concept. We have the scientific method, which we hope human practitioners follow properly, and do not lie about their results.

We are finding out this is actually a big problem, born of a social/cultural/monetary problem, which has little to do with “science.”

What we have today can best be called “scientism”

[mewzilla]

We don’t question science.

There is nothing wrong with the scientific method.

We question scientists.

And thats as it should be.

[mewzilla]

Well said!

[BipolarBob]

I am glad you have been able to recover. I have a friend on statins and they definitely have him going downhill but the doctors have scaremongered him to continuing as his mental faculties decline. Nothing I can do.

[dangus]

Your timeline is way off. DDT was first created in 1874, but first used in 1939 and would’ve taken years to build up in the environment. There was a major polio outbreak in 1916. Polio’s worst outbreak peaked was 1952... slightly before the polio vaccine was released (1955), but polio cases bounced up and down a LOT. DDT was banned in 1973, and its use barely declined prior to 1970.

[Rockingham]

No, Alzheimer's Disease was known long before statins were ever used in medicine. Based on my reading of the research literature, I believe that Alzheimer's and other dementias are mostly due to inadequate Vitamin D and magnesium wreaking havoc on cellular mitochondria. The result is an accumulation of damaged cells in the brain and in the cardiovascular system.

The preventative and the remedy are to take supplements of Vitamin D and amino acid chelated magnesium, especially magnesium L-threonate, and likely also Urolithin-A. These can improve cardiovascular function. They also help viable brain cells to clear out damaged mitochondria and replace them with new healthy mitochondria. In addition, magnesium is essential to over six hundred enzymatic reactions, including many that produce proteins vital to normal cell function.

[Valpal1]

The many replies pointing out the timeline that renders the book’s claim as specious should cause you to be suspicious of any other claims the author has made. Just sayinn.

[Grampa Dave]

Thanks for posting this reality for most of us!:

Maybe, but glad it was posed here on fr today- I hadn’t seen it before, and was under the impression that amyloid buildup was what brought on alzheimers from many articles I’ve read on the issue-

[BobL]

There will always be debate - my purpose here is to inform others.

[ransomnote]

This retraction may or may not be medical regime maneuverings.

The paper they are retracting purports to prove that "amyloid protein buildups caused the symptoms of Alzheimer's Disease ". The investigation of the paper started in 2022.

The Covid 'shot' is said by some independent researchers to create extensive amyloid plaques some of which collect in the veins/arteries and clog them with what looks like white strings, which some morticians have also reported finding.

A 69 year old woman with no other known illnesses had the following write up in her Covid 'vaccine' record in VAERS (Vaccine Adverse Events Reporting System). Note there never will be an investigation to prove what caused her illnesses, particularly as it looks like it may be the 'shot'. Sadly, no intervention is planned.

Doctor's Write-up: Had Moderna COVID vaccine approximately 1pm on 2/17. Developed headache and right visual field loss approximately 8pm on 2/18. Presented to our hospital at 5pm on 2/19 with progression of aforementioned symptoms and found to have left intraparenchymal hemorrhage with midline shift. Her symptoms are currently stable. Our neurosurgical team is not planning any surgical intervention. MRI of her brain demonstrates potential amyloid deposits, which are likely causative.

ransomnote: Another record for a 80 year old woman detailed that she already had dementia and issues with proteins in her body (amyloidosis), no one told her that the shot had proteins in it. Within 2 weeks of Covid 'vaccination' her eyes swelled, her hands hurt, she had pins/needles sensation up and down her legs, and she had some kind of episode at home (sensation over her body). The physician record notes 'aggravated condition', so 'the shot' probably doesn't play well with those who already have amyloidosis.

Of the 101 vaccines for which adverse events occurred after vaccination, only a handful reported the occurence of amyloidosis after Covid 'vaccination.' As usual, Covid 'vaccine' patients reported almost all of the cases of the symptom/illness in question.

I know medical fraud is rampant. But we've seen good medical papers retracted (lancet) or denied publication entirely (ivermectin, blood clots etc.) based on the censorship demands of the medical regime in D.C. in regards to the Covid 'shot. This may be a case of trying to detatch documentation from perhaps an upswing in dementia following covid 'vaccination' amyloidosis.

[9YearLurker]

I’m the senior writer and researcher, but it somehow just happened. How was I to know?

[Rockingham]

I agree that statins are problematic. Indeed, there is good evidence that they impair mitochondrial pathways, so they do damage that is compounded by inadequate Vitamin D and magnesium.

[steve86]

Claude:

Statins may reduce dementia risk: A 2018 meta-analysis of 31 studies involving over 3.3 million participants found that statin use was associated with a 15% reduced risk of dementia, including Alzheimer's disease and non-Alzheimer's dementia. The risk reduction was greater with higher statin doses and longer duration of use. Similarly, a 2023 study on over 15,000 patients with Alzheimer's or mixed dementia found that statin use, especially simvastatin, was associated with slower cognitive decline over time compared to non-users.

[TexasFreeper2009]

imagine the future retractions of all the global warming research!

[Reily]

Huge problem in scientific academia! There is no incentive to check papers for the accuracy of their claims. Academics that’s done peer review. It’s clear it isn’t. Peer review often degenerates into a sort of old-boy/girl network horse trading.

Redoing and experiment checking the results ought to be as a minimum a MS thesis for an aspiring BS degree. If the result claimed by the paper is important enough maybe even a PhD dissertation.

In the publish or persistent Academic environment with no incentives to check things this mess is what you get. Estimated that 75% of published papers aren’t reproducible!

[BobL]

Thanks - people think that things happen in a vacuum. But people don’t know jack about Cholesterol, not to mention what messing with it would do.

...and yet here we are!

[piasa]

The polio vaccine was available in the mid 1950s...
DDT wasn’t banned until the mid 1970s.

[If You Want It Fixed - Fix It]

Science don’t lie! You caveman!

[null and void]

We used to ride our bikes in the DDT cloud behind the fogger truck, just to watch the mosquitos drop dead around us.

That being said, there are a lot of organophosphate bug killers, and they do affect mammal nerves.