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Moderna COVID-19 vaccine prevented 95% of new infections after one dose in study
UPI ^ | 16 June A.D. 2021 | Brian P. Dunleavy

Posted on 06/16/2021 5:08:54 PM PDT by lightman

June 16 (UPI) -- A single dose of one of the two-shot COVID-19 vaccines prevented an estimated 95% of new infections among healthcare workers two weeks after receiving the jab, a study published Wednesday by JAMA Network Open found.

The first dose of the Moderna vaccine was 78% effective at preventing new cases just one week after clinical staff were inoculated, the data showed.

Still, 39, or just over 1%, of the nearly 3,400 health workers who received the vaccine later became infected with the virus, said researchers, from the VA Boston Healthcare System.

These "breakthrough" infections occurred at least 14 days after they had received their first dose, and 27 of them developed symptoms of the disease. RELATED Study: COVID-19 vaccine booster dose safe, needed for transplant patients

"[Even] at the height of Boston's winter surge, ... rapid first-dose vaccination of healthcare workers ... helped sustain healthcare delivery," study co-author Dr. Michael E. Charness told UPI in an email.

However, "full vaccination is still recommended for sustained immunity and protection against emerging variants," said Charness, chief of staff at the VA Boston Healthcare System.

Both two-dose COVID-19 vaccines, from Pfizer-BioNTech and Moderna, offer more than 90% protection against serious illness from the virus, research found. RELATED Expert: COVID-19 vaccines safe for kids, may allow return to 'normal life'

They work by using modified genetic material from the coronavirus to stimulate the production of antibodies, or cells that fight off infections, by the immune system, according to the Centers for Disease Control and Prevention.

This essentially primes the immune system to respond when or if a vaccinated person is exposed to the virus, the agency says.

Although studies have found that one dose of either of the two-shot vaccines offers at least some protection against the virus, they are most effective among those who are considered "fully vaccinated," defined as two weeks after receipt of the second shot. RELATED CDC: 2-dose vaccines reduce COVID-19 infection risk by 91%, limit virus spread

For this study, Charness and his colleagues assessed the effectiveness of one dose of the Moderna vaccine in more than 4,000 healthcare workers at the VA Boston Healthcare System during the winter spike of COVID-19 cases in the Boston area.

Just under 3,400, or about 84%, of the staff had received one dose of the vaccine by the end of the 42-day study period on Feb. 1, the researchers said.

Among the included healthcare workers, 107 new COVID-19 cases were reported during the study period, the data showed.

Of these, 39 were in those who had received their first dose and 68 occurred in those who had not received a shot, according to the researchers.

"Vaccine effectiveness may vary depending on the age, exposure and health risks of a population and transmissibility of variants," Charness said.

"Our work was done at the time the [original Wuhan variant was dominant, [and] efficacy might be different with the currently prevalent variants," such as the B.1.1.7 or Delta strains, he said.


TOPICS: Business/Economy; Culture/Society; News/Current Events
KEYWORDS: chinavirusvaccine; coronavirus; covid19; covid1984; moderna; vaccince
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To: proust

Yup.

One time around the track was enough.

Maxxed the Tylenol but still “fully vaxxed!” HEH.


41 posted on 06/16/2021 7:48:49 PM PDT by lightman (I am a binary Trinitarian. Deal with it!)
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To: Jyotishi

Raise my Ebeneezer.

LOL.


42 posted on 06/16/2021 7:50:27 PM PDT by lightman (I am a binary Trinitarian. Deal with it!)
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To: House Atreides

Hear, hear!


43 posted on 06/16/2021 8:06:25 PM PDT by walkingdead (We are sacrificing American youth's future on the altar of our own fear. And it is a travesty.)
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To: lightman

Did Santa Claus give you the shot and the Easter Bunny drop by to see if you were OK. You got the shot, now lets see what is wrought from that decision

Choose, but do so wisely

still wearing your mask?


44 posted on 06/16/2021 8:07:19 PM PDT by 100American (Knowledge is knowing how, Wisdom is knowing when)
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To: lightman

How would they determine this?


45 posted on 06/16/2021 8:18:24 PM PDT by vigilante2
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To: 100American

Never the wore the mask unless absolutely required (and I pushed the envelope many a time) and ditched it for the face shield right after the second dose.

Ditched it altogether as soon as the CDC said “not required”.

If the sign says “please” I respond (nonverbaly) “no, thank you.”

“Request?” I deny.


46 posted on 06/16/2021 8:29:24 PM PDT by lightman (I am a binary Trinitarian. Deal with it!)
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To: Republican Wildcat

this “shot” has nothing to do with mumps Measles Polio Smallpox (or even covid)
entirely other functionality...great and unknown risk...


47 posted on 06/16/2021 9:30:49 PM PDT by DEEP_e
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To: Edward Teach

Israel vaccinated their whole population and now they have no more COVID. All their neighbors have cases and deaths holding steady or rising, but it’s gone in Israel.

Spin THOSE numbers.


48 posted on 06/16/2021 10:05:25 PM PDT by 2aProtectsTheRest (The media is banging the fear drum enough. Don't help them do it.)
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To: lightman

More creative statistical analysis. Nice. /s


49 posted on 06/16/2021 10:29:48 PM PDT by logi_cal869 (-cynicus the "concern troll" a/o 10/03/2018 /!i!! &@$%&*(@ -)
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To: proust

“hangover and hot flashes.”

THAT MEANS ITS WORKING!


With all due respect, how do you know it is working?

I have friends who have said they had nothing but a sore arm after the jab...less sore than shingles shots, etc. So does that mean it is not working for them?

In all seriousness, does a strong reaction mean it is really working, or are you just assuming this?

Would truly like to know.


50 posted on 06/17/2021 12:05:36 AM PDT by Freedom56v2 (If I wanted to live in China, I would move there!)
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To: Edward Teach

This is a RELATIVE reduction, not an absolute one. The ABSOLUTE reduction in transmission is about 1% for this and the other “vaccines”

Correct.

https://www.nakedcapitalism.com/2020/12/95-effective-may-not-mean-what-you-think-it-means.html

“in the world of drug advertising, the word “effective” does not mean what you think it means. The other way to look at effectiveness is this: Based on the numbers released from phase 3 trials, the Pfizer vaccine is 95% effective, but 1% of the time. In the same way, the Moderna vaccine is 94% effective, but 2% of the time.”


51 posted on 06/17/2021 12:40:42 AM PDT by Polynikes ( Hakkaa paalle)
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To: Polynikes; Edward Teach
Of course the higher reduction is relative. That means the vaccine works for exposed / high risk group people. The small absolute risk reduction means that natural immunity and vaccination have reduced the spread of the disease to where people are unlilely to get it.

Here's a simple example. The absolute risk reduction from the Ebola vaccine is tiny, about a thousandth of a percent. Does that mean you don;t need the Ebola shot before your canoe camping trip on the Ebola river? No, you'll need that along with malaria, hepatitis, etc. Your colloidal silver and quinine isn't going to cut it. And you'll be quarantined when you return.

52 posted on 06/17/2021 4:35:18 AM PDT by palmer (Democracy Dies Six Ways from Sunday)
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To: lightman

My mother just passed away due to a stroke, about a month after receiving her 2nd dose. My uncle also had a mini-stroke around the same time-frame (still alive as of now). There is no history of stroke in my family that I’m aware of. I asked them not to do it, but it fell on deaf ears.


53 posted on 06/17/2021 5:47:08 AM PDT by TheElectionWasStolen
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To: lightman

“Still, 39, or just over 1%, of the nearly 3,400 health workers who received the vaccine later became infected with the virus, said researchers, from the VA Boston Healthcare System.”

To make sense of this, I need to know either the infection rate of an unvaccinated control group, or the time period over which these infections occurred.


54 posted on 06/17/2021 5:55:49 AM PDT by rightwingcrazy (;-,)
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To: lightman

The pandemic is over in America, at least that’s what the scientific data says: https://covid.cdc.gov/covid-data-tracker/#trends_dailytrendscases


55 posted on 06/17/2021 5:56:56 AM PDT by 1Old Pro (Let's make crime illegal again!)
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To: Republican Wildcat

it’s beyond that. By his previous posts he does not think bacteria and viruses cause the diseases


56 posted on 06/17/2021 6:01:14 AM PDT by Mom MD ( )
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To: palmer
That may be true but to market to the public as 95-94% efffctive is duplicitous at best with out clearly stating how those number are arrived at. When you start telling little white lies for the greater good you lose your credibility.

From the linked article on the previous post

“To a lay person, a phrase like “95% effective” means one of two things: either that she or he,
upon exposure to the virus, is protected 95% of the time, or that 95% of the people who take
the vaccine are protected 100% of the time.
And this is where the mutual eagerness of the two highly motivated groups — the public; the
profiteers — intersect. The public wants to hear “95% effectiveness” and think it knows what
those words means. The drug companies want the same thing as the public; it wants the
public to think it knows what those words mean.”

57 posted on 06/17/2021 9:24:30 AM PDT by Polynikes ( Hakkaa paalle)
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To: Polynikes
It;s not a white lie to talk about how effective the vaccine is. It is very effective if you are exposed. But since the risk of exxposure is very low, the vaccine is not necessary anymore. Why is that?

Because of natural immunity from in at least 1/3 of Americans, maybe 40%, who got COVID and got over it, most of them easily. What is the second reason? Because 65% of Americans have had at least one dose of vaccine. That's a big part of what makes the chance of getting COVID lower for everyone, vaccinated or not. Leaving that out is a lie of omission.

58 posted on 06/17/2021 7:31:17 PM PDT by palmer (Democracy Dies Six Ways from Sunday)
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To: palmer

And you can add another category. Due to the CV being about 60% the common CV strains that already existed, there are also people who already had sufficient antibodies needed per Dr. Yeadon.


59 posted on 06/17/2021 7:36:03 PM PDT by greeneyes ( Moderation In Pursuit of Justice is NO Virtue--LET FREEDOM RING)
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To: palmer
You can parse words till the cows come home. It all depends how you define “white lie” and how you present it to your target population.

The average lay person has no idea what determines true efficacy. To label an experimental modality the way its being marketed borders on criminal behavior. Just because you can do something doesn't mean you should. If enough people end up being hurt or killed the blow back will be extreme.

The whole process will undermine the physician-patient relationship for years. Welcome to the low trust society.

60 posted on 06/17/2021 8:41:48 PM PDT by Polynikes ( Hakkaa paalle)
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