Posted on 04/24/2020 10:51:32 AM PDT by SeekAndFind
Patients treated with hydroxychloroquine have no better chance of survival than those who don't receive the drug hailed by Trump as a 'game-changer', results of a New York state Health Department trial suggest.
'I think from the review that I heard basically it was not seen as a positive, not seen as a negative,' said Governor Andrew Cuomo during CNN's coronavirus town hall.
Ultimately, the study, conducted by SUNY at Albany, is intended to involved some 4,000 coronavirus patients, but the preliminary results are from a sample of 600 patients.
Survival rates were no better among the group treated with the experimental drug than among those who got the standard supportive care, including oxygen, IV fluids and, if necessary, mechanical ventilation.
On Friday, shortly after preliminary results were reported, the Food and Drug Administration (FDA) formally warned against using the drug outside of hospitals due to the risk that it could cause heart arrhythmias.
It's a major blow to President Trump, who has sung the praises of the drug, as well as to the global search for an effective treatment for coronavirus.
More than 50,000 Americans have died of coronavirus, and 890,000 have been infected.
Officials and doctors alike have hoped that hydroxychloroquine, a drug developed nearly half a century ago to treat malaria, might improve coronavirus patients' odds by combating severe inflammation resulting from the viral infection.
In lab tests, the drug showed promise, appearing to quell the 'cytokine storm' of immune signalling cells that causes inflammation to run wild in the body, overwhelming the lungs.
Hydroxychloroquine interacts with the human immune response, making it useful in treating autoimmune diseases like lupus.
It was even added the official lists of treatments to try for doctors treating COVID-19 patients in China and South Korea,
(Excerpt) Read more at dailymail.co.uk ...
First of all Cuomo would NOT let anyone have these drugs UNTIL they were hospitalized the drugs NEED to be given to AVOID hospitalization as far as I am concerned Cuomo has death on HIS HANDS forbidding doctors to try this in early stages with their patients!!
All the media , including international are running with Trump said drink Lysol which he never said.
It goes to show how dumb, ignorant and stupid people are when they believe the media today. Also how the media twists his words to attack him. Not hardly has the media stated he was asking about possible ways to combat this virus
NY hospitals make $30K from the Feds per intubated COVID death. They have financial incentive to discount Chloroquine.
Yes, the timing of the administration of any medicine or medical device is important, as to the efficacy of their use.
If Hydroxychlorquine is not part of early treatment, which can prevent mounting, snowballing effects of the initial impact of the Wuhan Virus - hpoxia, then yes, ancillary damages due to that initial problem mount and those damages are not directly offset by Hydroxychlorquine, and other interventions are needed, and yes, by then, patients with or without Hydroxychlorquine may do similarly.
But if the patient gets to the doctor in the early stages, and if the doctor puts them on Hyrdroxychlorquine, severe complications can often be avoided.
So yes, in any study the stage of illness with each patient, when Hyrdoxychlorquine is administered must be registered and results categorized by stage of the illness, or it is not a valid study.
Correction— the AZT add on group was not for everyone in the trial... just median age of 68.
Also and this is very important: This was a self selected study of more severe cases more likely to be prescribed the drug.Thus more likely these patients were to be fatal cases regardless of the treatment. And finally the drugs weren’t administered early enough to alleviate the symptoms to result in recovery, a critical element to the French trial was its immediacy of treatment upon positive test. Early— not by the time they were symptomatically admitted to a hospital— days after they “came down” with it. Thus-— TOO damned late.
Poor trial design, selected for soon to be dead patients who could not have enough time for the therapy to slow down the internal spread of their infection. Not just my humble opinion— experts see this for what it is, political as hell.
They don't even have any real results yet since they don't appear to have published anything, or even finished any kind of meaningful study.
As of April 22nd, 48 hours ago:
"We have reviewed several hundred medical records of Covid patients at this point in over 20 hospitals and done a preliminary analysis," David Holtgrave, the lead researcher, said Wednesday.
...
The New York study has been particularly anticipated because of its size -- some 1,600 subjects -- and because it's sponsored by the state and done by a respected group of epidemiologists at the University at Albany.
CNN and their leftist friends are really pushing the "respected epidemiologists" since Professor Holtgrave, the lead researcher, isn't an MD. He is however probably a solid Democrat:
"During President Barack Obama's Administration, Dr. Holtgrave served as a member and then Vice-Chair of the Presidential Advisory Council on HIV/AIDS"
Sadly that seems true. In this case 48 hours ago the lead researcher, Professor David Holtgrave told CNN:
"We have reviewed several hundred medical records of Covid patients at this point in over 20 hospitals and done a preliminary analysis," David Holtgrave, the lead researcher, said Wednesday.
...
"The New York study has been particularly anticipated because of its size -- some 1,600 subjects -- and because it's sponsored by the state and done by a respected group of epidemiologists at the University at Albany."
So 48 hours later it is unlikely that he or anyone else has done much serious analysis, or anything but appear on CNN to provide talking points.
I doubt Holtgrave could answer even simple questions about the dataset he is apparently still in the process of collecting.
That is after all how we found out about it.
We have seen dozens of them. But this venue won’t publish those.
I couldn’t find thread (many threads), but seems I read a sentence or two that indicated that hydroxychloroquine wasn’t helping late stage COVID-19 victims.
Also, NY was sending COVID-19 patients back to guest homes.
THIS EXPLAINS THE NEW YORK NUMBERS: Governor’s Policies Required Infected Coronavirus Patients Be Sent Back to Nursing Home
Figure that one out. The should have used underutilized floating hospital that PDJT sent them. I suspect a politically correct, “Orange Man Bad,” stand-down order on using PDJT’s hospital.
Corrections, insights welcome.
Send "Orange Man Bad" federal and state government Democrats and RINOs home in November!
Supporting PDJT with a new patriot Congress and state government leaders that will promise to fully support his already excellent work for MAGA and stopping COVID-19 will effectively give fast-working Trump a third term in office imo.
MAGA, also KAGA! (Keep America Great Always!)
:In New York, no patient can be given hydroxychloroquine as an outpatients”
not true. (personal experience)
Pharmacies in NYS have been directed by Gov. Cuomo NOT to fill off-label prescription.
Many doctors stockpiled HC prior to the executive order, and have been dispensing it.
Zelenko's original prescription was for 220mg zinc sulfate. I got a hold of some zinc gluconate and found something on line about how much zinc is in different formulations.
200mg of zinc sulfate has about 50mg of zinc. The zinc gluconate has about .143mg zinc per mg, so you'd need 350mg to get the same zinc content. I don't recall if the source I read had figures on zinc picolinate.
Of course, how much gets into your system with each of these would make a difference as well. I wonder how much additional zinc is necessary to have therapeutic effect.
I didn’t see a mention of zinc at all. The zinc is needed to keep the virus from replicating. Normal blood zinc levels are not enough.
They’re going after the HCQ treatment like the Orcs at Helm’s Deep...
“...Cuomo has death on HIS HANDS forbidding doctors to try this in early stages with their patients!!”
Is Fredo’s brother Andy a DOCTOR?
Actually (technically) he is!
(Andrew Cuomo) “He received a B.A. from Fordham University in 1979, and a J.D. from Albany Law School in 1982.
The Juris Doctor degree (J.D. or JD), also known as the Doctor of Jurisprudence degree (J.D., JD, D.Jur. or DJur), is a graduate-entry professional degree in law and one of several Doctor of Law degrees.
NOT a physician, MEDICAL doctor in any case!
NY has had the most incompetent health dept of any state
The state cases reflect this
There are other studies going on
This by Novartis is in stage 3 already
https://finance.yahoo.com/news/novartis-initiate-hydroxychloroquine-study-coronavirus-153503577.html
Dozens? There is Zev Zelenko, Steven Smith, a California doctor at an urgent care, Didier Raoult in France, and only the last has written up his results as opposed to talking about them in interviews.
Studies, at least retrospective. Patient data, age, sex, weight, smoker, prior conditions, meds, disease course, when treatment started. Were patients tested.
So...they gave patients everything...except the one thing that actually stops the virus replicase - zinc.
Without zinc, the studies are worthless, since zinc is what was clinically tested in the original SARS virus, and found to be highly effective.
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