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Study finds no benefit, higher death rate in patients taking hydroxychloroquine for Covid-19
CNN Fake News ^ | 21 April 2020 | Elizabeth Cohen and Dr. Minali Nigam

Posted on 04/21/2020 2:49:58 PM PDT by Magnatron

Coronavirus patients taking hydroxychloroquine, a treatment touted by President Trump, were no less likely to need mechanical ventilation and had higher deaths rates compared to those who did not take the drug, according to a study of hundreds of patients at US Veterans Health Administration medical centers.

The study, which reviewed veterans' medical charts, was posted Tuesday on medrxiv.org, a pre-print server, meaning it was not peer reviewed or published in a medical journal. The research was funded by the National Institutes of Health and the University of Virginia.

In the study of 368 patients, 97 patients who took hydroxychloroquine had a 27.8% death rate. The 158 patients who did not take the drug had an 11.4% death rate.

"An association of increased overall mortality was identified in patients treated with hydroxychloroquine alone. These findings highlight the importance of awaiting the results of ongoing prospective, randomized, controlled studies before widespread adoption of these drugs," wrote the authors, who work at the Columbia VA Health Care System in South Carolina, the University of South Carolina and the University of Virginia.

Researchers also looked at whether taking hydroxychloroquine or a combination of hydroxychloroquine and the antibiotic azithromycin, had an effect on whether a patient needed to go on a ventilator.

(Excerpt) Read more at cnn.com ...


TOPICS: Culture/Society; Government; News/Current Events; Politics/Elections
KEYWORDS: 1moretime; chat; chatforum; coronavirus; fakenews
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To: Tolerance Sucks Rocks

The sooner the protocol is started, the better it works. Dr. Zevlenko’s videos testify to this.


61 posted on 04/21/2020 5:21:37 PM PDT by Trumpisourlastchance
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To: Magnatron
National Institute of Health study published in 2005!

Chloroquine is a potent inhibitor of SARS coronavirus infection and spread

Conclusion: Chloroquine is effective in preventing the spread of SARS CoV in cell culture. Favorable inhibition of virus spread was observed when the cells were either treated with chloroquine prior to or after SARS CoV infection. In addition, the indirect immunofluorescence assay described herein represents a simple and rapid method for screening SARS-CoV antiviral compounds.

62 posted on 04/21/2020 5:38:04 PM PDT by saywhatagain
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To: shoe212
Yes, it is VERY possible that HCQ was given only to the sicker patients.

It is not just very possible, the authors state it clearly:

However, hydroxychloroquine, with or without azithromycin, was more likely to be prescribed to patients with more severe disease, as assessed by baseline ventilatory status and metabolic and hematologic parameters. Thus, as expected, increased mortality was observed in patients treated with hydroxychloroquine, both with and without azithromycin.

I suppose studies like this do have a value. They teach us how to get bad results from HCQ+AZ: wait as long as possible before starting the drug combo.

Meanwhile, back in France, Dr. Didier Raoult has continued to treat COVID-19 patients with HCQ+AZ. As of today, 2,999 COVID-19 patients have been treated with the drug combo. Among patients who received the drugs for more than three days, there have been 12 deaths.

63 posted on 04/21/2020 5:41:12 PM PDT by TChad (The MSM, having nuked its own credibility, is now bombing the rubble.)
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To: lonestar67

Bookmsrked, thank you!


64 posted on 04/21/2020 5:43:58 PM PDT by Robert A Cook PE (I can only donate monthly, but ABCNNBCBS donates every hour, every night, every day of the year.)
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To: higgmeister
With the way they present this, these reprehensible villains are seeming to imply that hydroxychloroquine kills.

See post #63. They admit that patients who received HCQ were likely to be sicker than those who did not. This is yet another example of what happens when docs use HCQ+AZ as a treatment of last resort, instead of administering the drugs immediately to anyone with a positive COVID-19 test.

When HCQ-AZ studies involve only hospitalized patients, expect poor results.

65 posted on 04/21/2020 6:07:34 PM PDT by TChad (The MSM, having nuked its own credibility, is now bombing the rubble.)
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To: Magnatron

CNN is an arm of the Democratic National Committee. Of this there is no question. Otherwise, why would they be printing something that doctors have said is working? They are really sleezy!


66 posted on 04/21/2020 6:22:26 PM PDT by maxwellsmart_agent
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To: Magnatron

ABC radio news did a lengthy blurb on this earlier this evening. You could almost sense the glee.


67 posted on 04/21/2020 6:35:59 PM PDT by Yardstick
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To: Magnatron

It is in CNN’s interest that more people die from CCP virus. Keep the fear, the destruction, the isolation going. Push vaccines, microchipping, totalitarian control.
They are in league with the CCP cartel


68 posted on 04/21/2020 8:49:07 PM PDT by boxlunch (Pray for President Trump! Break up the Chicomm/Demomafia/Lying media/Deep State cartel)
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To: DoodleDawg

How do you know that Zelenko is telling the truth and the Veteran’s Administration is lying? >>>>>>>>>>>>>

1) Because if Dr. Zelenko is lying, he will lose his license to practice medicine.

2) He is a man of God, one recognized and lauded by his fellow Hassidic Doctors all over the world, as well as New York State. Why would he lie for fickle fame and fortumne/ If so, he wour br pilloried by his fello physicians in the hassidic community. The Hasidim praise him for saving the Hassidim of his own community from the Angel of death during Passover. Dr. Z brought passover in a very real sense.

No.

Dr. Zelenko is not a liar.

He’s a hero for suffering the slings and arrows of the left and people who are prejudiced against Jews.Dr. Z stuck to his guns despite threats and anti-Semitic attacks,, thank God, and now lives are being saved all across our nation and abroad.

As to the veterans administration, tey are likely waiting too long to administer the treatment, or are not using the correect supprtive drugs. The Dr. Z treatment cannot be adm inisterd as if its some magic bullet. For best results it needs to be administered before the disease evolves to fill the lungs with mucus, and temperature spikes up t 104 degrees Fahrenheit.The reason the VA likely waited to long is that they did not do a diagnosis without waiting for test results.The tests would take too long and the disease became too developed and involved Big Mistake.Many were too far gone for the HCQ therapy to help them because the VA doctors waited too long.


69 posted on 04/21/2020 8:55:35 PM PDT by Candor7 (Obama Fascism:https://www.americanthinker.com/articles/2009/05/barack_obama_the_quintessentia_1.html)
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To: Trumpisourlastchance

Yep, as soon as you’re diagnosed, NOT when you have the vent tube down your throat.


70 posted on 04/22/2020 1:34:30 AM PDT by Tolerance Sucks Rocks (Wu Flu! (when I feel heavy metal) Wu Flu! (when I'm pins and I'm needles) Wu Flu!)
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To: Magnatron
So, they "reviewed veterans' medical charts" and called it a "study" but provide zero actual data about the patients' original health/age/stage of illness before the dosing, etc....

I can pull a more relevant study outta my butt any given second of a day...but I call it the proper term...."An Obama"...

71 posted on 04/22/2020 4:00:09 AM PDT by trebb (Don't howl about illegal leeches, or Trump in general, while not donating to FR - it's hypocritical.)
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To: Magnatron

Here is the paper CNN used for their article:
Outcomes of hydroxychloroquine usage in United States veterans hospitalized with Covid-19
https://www.medrxiv.org/content/10.1101/2020.04.16.20065920v1
https://www.medrxiv.org/content/10.1101/2020.04.16.20065920v1.full.pdf

This is NOT a clinical study.
As the authors point out, it is a retrospective analysis of data from patients hospitalized with confirmed SARSCoV-2 infection in all United States Veterans Health Administration medical centers.
They analyzed the covid19 patients treated with HC, with HC+AZ, and those not treated with HC.
No mention of Zinc added.

NIH is not an impartial agency.
Two of the authors of this paper have competing interests listed in acknowledgements. One of the authors is funded by Gilead Sciences, which holds the patent on remdesivir, a competing Covid-19 drug.

Since this is a study looking at data from VA Hospitals across the country, it would seem important to mention the DOSAGE of the Hydroxychloroquine and the Azithromycin and HOW LONG the patient was on the drugs. Evidently, no Zinc was added, which is part of the protocol for some of the successful studies.

A few statements in the article indicated the data was massaged.
1) Baseline demographic and comorbidity characteristics were comparable across the three treatment groups. However, hydroxychloroquine, with or without azithromycin, was more likely to be prescribed to patients with more severe disease, as assessed by baseline ventilatory status and metabolic and hematologic parameters. Thus, as expected, increased mortality was observed in patients treated with hydroxychloroquine, both with and without azithromycin. Nevertheless, the increased risk of overall mortality in the hydroxychloroquine-only group persisted after adjusting for the propensity of being treated with the drug.
2) We analyzed the association of HC or HC+AZ use with the risk of overall death and the risk of ventilation as the primary outcomes. As baseline characteristics corresponding to clinical severity varied across the three groups of patients and could have influenced the non-randomized utilization of hydroxychloroquine and azithromycin, we computed propensity scores for HC use and HC+AZ use based on all baseline characteristics.

The propensity score for a subject is the probability that the subject was treated, P (T=1). In a randomized study, the propensity score is known; for example, if the treatment was assigned to each subject by the toss of a coin, then the propensity score for each subject is 0.5.

If the VA hospitals allowed hydroxychloroquine to be used, it seems logical they also used remdesivir with Covid-19 patients.
Where is the VA hospital data for remdesivir? Might be worth investigating that data.
Maybe we could get Dr Oz to do this same type of analysis to remdesivir treated patients and those not treated with remdesivir. He seems to have access to this type of data.


72 posted on 04/22/2020 5:34:58 AM PDT by FR_addict
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To: Candor7
So then your argument is that it works because Zelenko said it does and we should believe him because you say we should?

That whole 'trust but verify' is completely lost on you, isn't it?

73 posted on 04/22/2020 5:49:16 AM PDT by DoodleDawg
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To: DoodleDawg

That whole ‘trust but verify’ is completely lost on you, isn’t it? >

He is a doctor.

He has to tell the truth or lose his license to practice medicine. Its simple.

I can easily become Dr. Z’s his patient without hesitation.

And you?

You want to find a politically correct, not a “scientific” doctor.Trust and verify your own doctor. I am free to do so. Unless you want to bet who would be alive between you and I? LOL.

Good luck to you and also to all of the anti-Semitic folks who would rather die than believe a duly licensed Jewish physician.


74 posted on 04/22/2020 9:31:51 AM PDT by Candor7 (Obama Fascism:https://www.americanthinker.com/articles/2009/05/barack_obama_the_quintessentia_1.html)
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To: Candor7
Its simple.

Of course it is.

I can easily become Dr. Z’s his patient without hesitation.

And you?

I'll stick with my local doctor thank you.

Good luck to you and also to all of the anti-Semitic folks who would rather die than believe a duly licensed Jewish physician.

How do you know that none of those VA doctors you believe are lying aren't Jewish also?

75 posted on 04/22/2020 10:18:57 AM PDT by DoodleDawg
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To: DoodleDawg

How do you know that none of those VA doctors you believe are lying aren’t Jewish also? >>>>>>>>>>>>>>

I didn’t say the VA doctors were lying. They truly do not know the proper way to administer HCQ theapy. Dr. Zelenko does. I guess he will have to teach them, going on a nationwaide trip to show them how its done.


76 posted on 04/23/2020 7:09:34 PM PDT by Candor7 (Obama Fascism:https://www.americanthinker.com/articles/2009/05/barack_obama_the_quintessentia_1.html)
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