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The following thread regards how we should be planning for the possibility that nCoV cannot be contained (Tweets from J. Hopkins Director)
Twitter ^ | January 26, 2020 | Tom Inglesby

Posted on 01/26/2020 8:05:50 PM PST by DoodleBob

Containment of nCoV is, and should be, the highest priority in China. This requires gov, health care/PH system & the public to work together to ID those w/ sx, get them tested rapidly, get them isolated (home or hospital), provide good med care while keeping HCWs protected. (2/x)

The global community should be doing all it can to be helping China w/ the terrible set of challenges it is facing in its effort to contain nCoV. It is not only the right thing to do for China, but it is critical in trying to help prevent global spread. (3/x)

We don’t know what overall CFR will be w/ nCoV-that requires more data, time. SARS-like illness has been seen in some, but we don’t know what % of nCoV pts will get severe disease. We all hope it'll be far less than SARS, but we don’t know enough to predict %. (4/x)

We also don’t have enough data on H2H transmission yet to make confident predictions about how it will spread. We don’t know enough about extent of asymptomatic cases, asymptomatic spread, proportion of spread happening in health care facilities vs community. (5/x)

But given uncertainties + very high stakes, part of global & national planning efforts should now be aimed at possibility that nCoV containment could fail. (6/x)

Others have raised this possibility too, including @neil_ferguson at Imperial who has said in last 24 hrs that containment of nCoV might not succeed. (7/x)

Global and national leaders should be looking ahead to what must be done to prepare for the possibility nCoV can’t be contained, even as we continue to work as hard as possible to contain it in China and beyond. (8/x)

The work to prepare for the possibility of failed containment could be called something like: Plan for Global Mobilization to Respond to a nCoV Pandemic. There are a series of highest priorities that should be at the top of that Plan, including: (9/x)

Crash vaccine development. Top of list because would so dramatically change response and outcomes. @NIAID & @CEPI working on vaccines, as are others. All pharma+biotech companies that could have a vaccine or therapy candidate of relevance should be enlisted in the effort. (10/x)

Multiple vaccine efforts should be pursued in parallel. Money should not be rate-limiting. Timelines should be shortened in whatever ways possible that doesn’t get in the way of a final safe, effective product. Rapid clinical trials prepared. (11/x)

Global plan for mass manufacturing of vaccine when it is created. This should be planned for multiple places in the world concomitantly. Cannot have a successful vaccine come out of only one place and remain only in that country. It will need to be broadly distributed.(12/x)

Plan for WHO global stockpile w/ global allocation plan. Once vaccine developed, WHO will need to allocate vaccine quickly to countries around world. WHO can work w/ UN system to help distribute, but will also need partnerships w/ global logistics companies to succeed. (13/x)

Urgent serology development programs. Need this to help determine severity of nCoV. If many have been exposed and are immune, but never had disease, this suggests asymptomatic spread and that disease will be mild in many. We need serology testing. (14/x)

Massive expansion of diagnostics development capacity in China and around world. We need diagnostics to isolate and triage and care for people, and if containment fails will need very high numbers of reliable diagnostic tests around the world in the months ahead. (13/x)

Rapid clinical trials for antivirals. There isn't much evidence current antivirals will be useful, but there should be in vitro studies, clinical trials to study all reasonable candidates. Other med interventions that have sound theoretical basis should be studied quickly. (16/x)

Major expansion of personal protective equipment for health care workers. We have seen in SARS that much of the spread of disease is through hospitals. We will need to make sure health care workers have needed equipment to protect themselves. (17/x)

Hospital infection control plans. Beyond protecting health care workers, hospitals will need administrative plans, equipment, engineering controls where relevant, to care for higher number of patients at same time they are working to prevent resp spread of disease. (18/x)

Government plans to provide transparent, full, rapid communication. People need to trust that governments giving them the full story so that they will agree to get tested, isolated and treated. (19x)

Good accurate info needs to flood out the bad, the harmful rumors, the conspiracy info. Govs may need to partner w traditional and social media to get factual info out to people. (20/x)

Plans to keep travel&trade moving in the world, even if we do have disease spread around the world. nCoV airport screening efforts make sense now as a way of early ID of pts. But if containment fails and disease is widespread in world in time ahead, new plans are needed. (21/x)

If nCoV spreads widely in the world, it will be in strong interest of all countries, to keep trade going despite the pandemic– global economy is highly interdependent. Govs would need to work w/ orgs like WTO and travel industry orgs like IATA to keep goods, people moving.(22/x)

Certainly there are other key elements of such a Global Plan, and additional recommendations welcome here. (23/X)

Overall in this Planning effort, countries will need to take some actions on their own. Others will require international coop. e.g. many countries don't have capacity to develop, make vaccines, Dxs, masks, et al so will need to work w/ countries that do. (24/x)

Other elements of this Plan will require close cooperation between countries, global business and international orgs. Organization of the elements of this Global Planning effort will be hard and consuming. (25/x)


TOPICS: News/Current Events
KEYWORDS: asia; china; coronavirus; coronovirus; disease; hysteria; johnshopkins; manthelifeboats; pandemic; panicbrigade; prepper; preppers; shtf; teotwawki; virus; who; wuhan; wulan
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To: yesthatjallen

Colloidal silver isn’t banned.

https://bit.ly/2RN08nu


81 posted on 01/26/2020 10:42:59 PM PST by Pelham (RIP California, killed by massive immigration)
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To: cherry

Amazon has it. Be careful, everybody is turning blue! Not. LOL


82 posted on 01/26/2020 10:46:10 PM PST by Karl Spooner
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To: Pelham; yesthatjallen

We use it for burns. Always have. Too much is too much, permanent side effects.

I was told by a good source not sure if true. The silversmiths were spared during the Black Plague.

I was also told it’s good use silverware.


83 posted on 01/26/2020 10:46:55 PM PST by stanne
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To: Pelham; yesthatjallen

We use silver for burns, I mean in the hospital.


84 posted on 01/26/2020 10:49:02 PM PST by stanne
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To: Jane Long

I’m guessing Thorazine for that one.


85 posted on 01/26/2020 10:52:44 PM PST by Pelham (RIP California, killed by massive immigration)
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To: ProtectOurFreedom
"My son starts his ambulance internship for his Paramedic license this Friday. His coverage area is San Mateo County where SFO is located with LOTS of Asian passengers. I just asked him if he’s been trained on 2019-nCoV diagnostics and how to protect himself, when to put on PPE, etc. Haven’t heard from him yet."

Our son is an EMT in an emergency room on the East Coast. I asked him about training as well. They have been instructed to add one question to the intake protocol. They are to ask whether the patient has traveled out of the country recently, and if so, put them in a positive pressure isolation room. That's it. No discussion of personal protective equipment or other precautions. I reminded him of frequent hand washing and keeping his hands off his face. I will ask again in a few days to see whether they update the guidance. Treading lightly . . .

86 posted on 01/26/2020 10:53:21 PM PST by Think free or die
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To: Salamander

There you go, spoiling the magical thinking with evidence ‘n stuff


87 posted on 01/26/2020 10:56:42 PM PST by Pelham (RIP California, killed by massive immigration)
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To: yesthatjallen
That guy is an idiot. He made his own and didn't know what the heck he was doing. I have used CS for 25 years and I am not the slightest shade of blue. Never make it with salt, that is the first thing you learn when making your own. lol

"He got this condition by taking his homemade silver compound that was mostly a highly concentrated ionic silver solution. When he prepared the solution he believed he was making colloidal silver. He was not making colloidal silver.

To make the solution even more dangerous, he added salt to the brew and then used electrolysis to make a high concentration of silver chloride with large particles which is well known to cause argyria.

He further applied the compound to his skin causing him to become an internal and external photographic plate. To finish himself off, he used a tanning bed to "fix" the silver in his body."

88 posted on 01/26/2020 11:01:39 PM PST by Karl Spooner
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To: Think free or die

Positive pressure? I hope you mean negative pressure.


89 posted on 01/26/2020 11:01:47 PM PST by LukeL
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Comment #90 Removed by Moderator

To: rxsid

You multiplied by 100 two times in the equation.


91 posted on 01/26/2020 11:04:55 PM PST by LukeL
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To: Pelham
The article misidentifies the term banned.

"In August 1999, the U.S. FDA banned colloidal silver sellers from claiming any therapeutic or preventive value for the product, although silver-containing products continue to be promoted as dietary supplements in the U.S. under the looser regulatory standards applied to supplements. The FDA has issued numerous Warning Letters to Internet sites that have continued to promote colloidal silver as an antibiotic or for other medical purposes. Despite the efforts of the FDA, silver products remain widely available on the market today. A review of websites promoting nasal sprays containing colloidal silver suggested that information about silver-containing nasal sprays on the internet is misleading and inaccurate."

https://en.wikipedia.org/wiki/Medical_uses_of_silver#Adverse_effects

Even so CS doesn't seems to have any real practical advantages taken internally. As an old fashioned topical ointment it may inhibit bacterial infections to an open wound. Ingested for extended periods the problem is obvious.

Argyria

The Dangers of Colloidal Silver

92 posted on 01/26/2020 11:10:05 PM PST by yesthatjallen
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To: Artcore
it may or may not be serious and devastating......

we have hurricane threads for days....

we have a certain alphabet thread that just keeps reoccurring....

I think a daily thread for us that want to read is a good thing...others may just pass it by, its their choice....

myself....I'd rather have the latest information....

93 posted on 01/26/2020 11:10:18 PM PST by cherry
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To: rxsid

According to the mayor of Wuhan, 5 million of the population left before quarantine was applied. It’s Chinese New Year.

This virus is transmissible up to 10-14 days before symptoms appear; there are documented cases of doctors who were not in Wuhan, catching from doctors who had been there, merely by sitting next to them at a conference.

Beijing, two days ago, announced the designation of TWENTY hospitals to hold coronavirus patients. This was back when Beijing only had announced ten patients.

Two entire hospitals per patient?

This case is different, because the authorities are ACTING different.

Even in the US, local health authorities are pulling people off planes, putting them in isolation in hospital rooms, and instituting contact tracing. When was the last time you heard of *that*?

France, South Korea, the US, and at least one other country I can’t recall, are chartering flights to remove their citizens from Wuhan. When did you ever hear of THAT for the flu?

Stop mouthing off and start reading up, mmmkay?


94 posted on 01/26/2020 11:15:43 PM PST by grey_whiskers (The opinions are solely those of the author and are subject to change with out notice.)
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Comment #95 Removed by Moderator

To: yesthatjallen; stanne

I use it for cuts. It’s a pre-antibiotic era germ killer probably on par with iodine. It might be harder for bacteria to have immunity to it since it’s not widely used these days. I’ve even tried using colloidal silver as a nasal swab since nothing else works on a cold; the jury is out on that one although I do think it helps. I’ll let you know if my nose turns bright blue as a consquence.


96 posted on 01/26/2020 11:23:08 PM PST by Pelham (RIP California, killed by massive immigration)
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To: pepsionice

Drugs and vaccines. Steve Hatfield said all vaccines are produced over seas now. Apparently Trump signed an EO funding a 5 to 6 year plan to bring up our domestic capabilities.


97 posted on 01/26/2020 11:25:05 PM PST by justa-hairyape (The user name is sarcastic. Although at times it may not appear that way.)
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To: grey_whiskers
My God, you’re both stupid and dishonest. Go throw yourself down a well next time, you tomfool of a Took, and rid us of your stupidity.

What did the poster write that warranted that sort of response?

98 posted on 01/26/2020 11:29:09 PM PST by Fury
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To: LukeL

He said positive pressure when he related the conversation. Since they aren’t putting the staff in protective equipment, perhaps they are genuinely more concerned about protecting the patient from incoming contaminants rather than the other way around. I’d sleep better if I saw them taking a more aggressive position to protect their staff, but it’s a decent hospital so hopefully they’ll be updating their protocols in the next days.


99 posted on 01/26/2020 11:29:33 PM PST by Think free or die
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To: Karl Spooner
Paul Karason was 62 when he passed away Monday in a Washington hospital, where he was admitted last week after suffering a heart attack. He also had pneumonia and later suffered a severe stroke, his estranged wife, Jo Anna Karason, said Tuesday.

Maybe he never got a cold or the flu but he suffered a heart attack, pneumonia, and a stroke.

Did he over do it? It sure looks like it but I don't see what good it did him.


100 posted on 01/26/2020 11:32:21 PM PST by yesthatjallen
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