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Chemical in red wine, fruits and vegetables stops cancer, heart disease, depending on the dose
EurekAlert ^ | 10/30/07 | Federation of American Societies for Experimental Biology

Posted on 10/30/2007 1:39:59 PM PDT by crazyshrink

Research in the FASEB Journal lays the groundwork for safe, new cancer therapy The next cancer drug might come straight from the grocery store, according to new research published in the November 2007 issue of The FASEB Journal. In the study, French scientists describe how high and low doses of polyphenols have different effects. Most notably, they found that very high doses of antioxidant polyphenols shut down and prevent cancerous tumors by cutting off the formation of new blood vessels needed for tumor growth. Polyphenols are commonly found in red wine, fruits, vegetables, and green tea.

At relatively low doses, the French researchers found that the same polyphenols play a beneficial role for those with diseased hearts and circulatory systems by facilitating blood vessel growth. The amount of polyphenols necessary for this effect was found to be the equivalent of only one glass of red wine per day or simply sticking to a healthy diet of fruits and vegetables containing polyphenols. This diet is known as the “Mediterranean Diet.” This study also adds to a growing body of research showing dose-dependent relationships for many types of commonly used compounds. For instance, research published in the October 2006 issue of The FASEB Journal shows that aspirin, through different mechanisms, also has a dose-dependent relationship for heart disease and cancer.

"When it comes to finding treatments for complex diseases, the answers are sometimes right there waiting to be discovered in unexpected places like the produce aisles and wine racks of the nearest store,” said Gerald Weissmann, M.D., Editor-in-Chief of The FASEB Journal. “But it takes modern science to isolate the pure compound, test it in the lab, and to go on from there to find new agents to fight disease.”

According to the authors, the amount of polyphenols necessary to obtain an anti-cancer effect is the equivalent of drinking about a bottle of red wine each day. This amount of daily alcohol consumption obviously is unhealthy, but the research suggests that polyphenols extracted from plants or red wine could be converted into a pill that is highly likely to be safe. Such a pill also would be relatively easy and inexpensive to create and deliver.

“The use of plant polyphenols as therapeutic tools presents important advantages,” said Daniel Henrion, senior author of the study, “because they have a good safety profile, a low cost and they can be obtained everywhere on the planet.”

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TOPICS: Culture/Society; Miscellaneous; Philosophy
KEYWORDS: cancer; diet; health; medicine; oenology; wine

1 posted on 10/30/2007 1:40:00 PM PDT by crazyshrink
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To: crazyshrink

I just saw supplements containing polyphenols at the local health food store.


2 posted on 10/30/2007 1:45:14 PM PDT by depenzz (If we don't put an effort into creating what we want, we must then tolerate what we get)
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To: crazyshrink

I’ve been taking grape seed extract for close to 20 years and have not had a cold or flu since then. Red wine on a daily basis is why that one French woman lived to over 120 years and she was a regular smoker.


3 posted on 10/30/2007 2:04:14 PM PDT by Mark (REMEMBER: Mean spirited, angry remarks against my postings won't feed even one hungry child.)
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To: crazyshrink

Don’t forget Dark Chocolate.


4 posted on 10/30/2007 2:17:22 PM PDT by Balata
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To: crazyshrink

for more info.


5 posted on 10/30/2007 2:22:13 PM PDT by Irish Eyes
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To: crazyshrink

Since when has, “a bottle of red wine each day” become “obviously ... unhealthy?”

Obvious to whom?

Hank


6 posted on 10/30/2007 2:31:05 PM PDT by Hank Kerchief
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To: crazyshrink
They sell Grape Seed Extract tablets at Sams..:)

sw

7 posted on 10/30/2007 2:35:28 PM PDT by spectre (spectre's wife)
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To: crazyshrink

“...to obtain an anti-cancer effect is the equivalent of drinking about a bottle of red wine each day. This amount of daily alcohol consumption obviously is unhealthy.”

LOL Not so obviously at all. What is a good dinner without a bottle of red wine? Kind of like a day without sunshine. LOL


8 posted on 10/30/2007 3:06:14 PM PDT by Continental Soldier
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To: crazyshrink

Another good source of polyphenols is pomegranate juice, which you can find in the juice isle at your local grocery store, which is good if you need the benefits but would like to avoid alcohol.


9 posted on 10/30/2007 8:10:21 PM PDT by Monitor (Gun control isn't about guns; it's about control.)
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