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SHOCK CASE REPORT: Advanced Alzheimer’s Patient Regains Speech, Memory, Mobility, and Bladder Control After a Single High Dose of Psilocybin-Containing Mushrooms
The Gateway Pundit ^ | October 4, 2026 | Jim Holt

Posted on 10/04/2026 6:12:15 AM PDT by Dr. Franklin

A stunning medical case is raising new questions about what may still be possible for patients suffering from advanced Alzheimer’s disease.

A Japanese-American woman in her 80s who had spent five years barely speaking, unable to walk on her own, and incontinent of urine started talking about her own life again roughly 19 hours after a single oral dose of psilocybin-containing mushrooms, according to a case report published May 28, 2026, in Frontiers in Neuroscience.

The paper, “Transient multidomain functional improvement in advanced Alzheimer’s disease following high-dose psilocybin-containing mushroom administration,” was written by Marcos Lago, Mariana Cerveira, and Joe Xavier Simonet of the Associação Cruz de Ankh in São Paulo, Brazil. It is one patient. It is not a randomized trial. The authors are explicit that the findings “do not imply disease reversal.”

The patient had a clinically diagnosed 10-year history of Alzheimer’s disease, including five years of marked hypofunction.

At baseline she spoke mostly in single syllables. She had chronic urinary incontinence, needed help to walk, could not dress herself, had a flat affect, trouble swallowing, and severe loss of spontaneous communication.

She lived under continuous family and caregiver supervision. Formal biomarker confirmation and advanced imaging were not available, and the authors note that a vascular or mixed contribution cannot be fully excluded.

With her son’s consent, she was given 5 grams of dried Enigma-strain Psilocybe cubensis by mouth. Importantly, that means 5 grams of mushrooms, not 5 grams of purified psilocybin.

The first stretch was rough. Clinicians suspected hyperthermia. She sweated heavily and dropped into a prolonged deep sleep-like state.

About 19 hours later, near 3:30 a.m., she woke on her own and began an autobiographical conversation that lasted roughly four hours. Her son reported memories and reflections nobody around her had heard her produce in years.

(Excerpt) Read more at thegatewaypundit.com ...


TOPICS: Miscellaneous; News/Current Events; Unclassified
KEYWORDS: alzheimers; hoftisafairy; hoftocd; mycology; psilocybin; shroomertrip

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So magic mushrooms might cure Alzheimer’s Disease.

I know that a mushroom called Lion's Mane is alleged to improve memory loss, so maybe they are on to something here.

1 posted on 10/04/2026 6:12:15 AM PDT by Dr. Franklin
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To: Dr. Franklin

“So magic mushrooms might cure Alzheimer’s Disease.”

Don’t be so quick to make a conclusion...because, if Big Pharma cannot make billions off it it, it’s DOA.


2 posted on 10/04/2026 6:17:52 AM PDT by BobL (Trusting one's doctor is the #1 health mistake one can make.)
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To: Dr. Franklin

This should liven up the parties at the senior centers.


3 posted on 10/04/2026 6:18:16 AM PDT by ansel12
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To: Dr. Franklin
" So magic mushrooms might cure Alzheimer’s Disease."

Not exactly. The human brain doesn't heal but it can regain some functions by rewiring neural pathways and/or offloading lost functions to other regions of the brain.

It isn't so much as cure as it is a work-around.

4 posted on 10/04/2026 6:19:52 AM PDT by Paal Gulli
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To: Dr. Franklin

Dude!


5 posted on 10/04/2026 6:26:14 AM PDT by Jeff Chandler (The issue is never the issue. The issue is always the revolution.)
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To: Dr. Franklin

She went on to become cosmically aware, her hair fell out, and her eyes began glowing yellow. Her new preferred method of transportation is levitation. She now prefers to be referred to as “Madam Mushroom”, and all who refer to her otherwise are instantly disintegrated.


6 posted on 10/04/2026 6:28:01 AM PDT by The Duke (Not without incident)
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To: BobL

True statement.


7 posted on 10/04/2026 6:31:46 AM PDT by OKSooner ("Thank you, Dr. Fauci!" /s)
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To: Dr. Franklin

Near the end of the article…“They frame it as residual function that may still be reachable under certain neuromodulatory conditions, not plaques dissolving, not a cure.”

I wonder if Musk’s team is working on Alzheimer in addition to sight and hearing.


8 posted on 10/04/2026 6:32:39 AM PDT by ProtectOurFreedom
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To: Dr. Franklin
improve memory loss

Not trying to be picking nits, but, wouldn't it be preferable to just say, 'stop memory loss, or slow down memory loss, or reverse memory loss'?

"Improving" a bad thing sounds like making the bad thing worse.
9 posted on 10/04/2026 6:36:39 AM PDT by adorno ( )
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To: Dr. Franklin

Assuming this story is scientifically proven, I have a belief that natural remedies exist that can effectively treat many of the common medical conditions that exist today.

Things live Ivermectin, mushrooms, etc., are either natural or are very inexpensive, these solutions are buried by the pharmaceuticals industry.


10 posted on 10/04/2026 6:40:14 AM PDT by srmanuel ( )
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To: BobL

I see you are a realist about the medical-pharma industrial complex.


11 posted on 10/04/2026 6:40:45 AM PDT by FreedomPoster (Islam delenda est)
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To: Dr. Franklin

A little off topic, but many cultures eat mushrooms, Poles, Lithuanians,Japs, etc....certain mushrooms have huge medicinal value.

I myself drink mushroom coffee every day, and when I miss just a day my body notices it. That said, there are many mushroom coffee blends out there, many taste like vomit.


12 posted on 10/04/2026 6:42:20 AM PDT by delta7
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To: Dr. Franklin
Psilocybe cubensis

What it is

A species of psychoactive mushroom containing psilocybin and psilocin (and smaller amounts of related tryptamines). These compounds act primarily as partial agonists at serotonin 5‑HT2A receptors.

Typical effects and timeline (oral ingestion)

-Onset: 20–60 minutes
-Peak: about 2–3 hours
-Total duration: roughly 4–6 hours (longer at higher amounts), with possible “afterglow” effects into the next day
-Psychological: intensified colors/sounds, altered time perception, enhanced introspection, euphoria; potential for anxiety, panic, confusion, paranoia, or distressing “bad trips”
-Physical: dilated pupils, increased heart rate and blood pressure, nausea/vomiting, tremor, sweating, dizziness, headache

13 posted on 10/04/2026 6:43:39 AM PDT by mjp (pro-freedom & pro-wealth $)
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To: BobL

Don’t be so quick to make a conclusion...

***********

Concousions go round and round. At some
point it could provide some data/info worth
using. Take care


14 posted on 10/04/2026 6:47:15 AM PDT by deport
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To: srmanuel

Things like Ivermectin, mushrooms, etc., are either natural or are very inexpensive, these solutions are buried by the pharmaceuticals industry.


Very true. Ivermectin, mushrooms and DMSO topical cream is in my primary toolbox. I credit those to my good health. Another tip, run from anything that has mRNA, mRNA kills and disables, as we have been witnessing.


15 posted on 10/04/2026 6:51:03 AM PDT by delta7
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To: Dr. Franklin

One of the things you notice after working with Alzheimer’s disease patients is that when the patient becomes angry or expresses intense emotion, their memory comes back and so does their speech.

I’ve heard them say more clearly in five minutes than they expressed in the preceding year combined, just by shifting their consciousness.

It has to do with amygdala consciousness processing vs hippocampal processing. The thalamus is responsible for focus and prioritizes which organ receives the signals.

This is one of the reasons that if you get an Alzheimer’s patient to sing, they often remember the words to the song when they don’t remember who you are, or their own name.

Singing shifts a person into an emotional consciousness.

When synthetics THC came out, like JWH-18 that was many times stronger than the plant based THC, first time users were developing schizophrenic attributes for the remainder of their life.

I worked with two different cases where young females used Ayahuasca and had similar psychological symptoms. The drug decreases ego which is masculine logical processing, shifting a person into emotional processing.

In these two cases, the young females had not self actuated and developed an ego identity. The Ayahuasca decreased what little ego identity they had developed and threw them back into an emotional consciousness, thus opening them up to hearing the schizophrenic voices.

My direct observation was the the drug increased activity in the right temporoparietal junction of the brain. The temporoparietal junction is an area of the brain where the temporal and parietal lobes meet, playing a major role in attention, language, and social processing.

To a lessor degree, the same attributes manifest when transcranial magnetic stimulation is used to stimulate the right temporoparietal junction of the brain.

Thus it would appear that drugs that decrease the hippocampal logical thought processing, the same aspect of consciousness that is dominant in Autism Spectrum and Asperger’s Syndrome disorders, blocks logical memory retrieval and forces a shift to emotional thought processing.

Maybe, this is why long term pot smokers lose their short term memory.


16 posted on 10/04/2026 6:57:16 AM PDT by tired&retired (Blessings )
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To: Dr. Franklin

So where can a person buy this identical drug?


17 posted on 10/04/2026 6:57:28 AM PDT by BipolarBob
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To: Dr. Franklin

These “shrooms” are illegal in Canada but the law isn’t enforced and you can even get them delivered to your address. Neat huh? I know that this is a fact in Toronto at least. Take a trip to Canada...then “you can never leave the farm.”


18 posted on 10/04/2026 6:59:46 AM PDT by know.your.why
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To: All

Plus she gained the ability to fold Space and unlock racial memories


19 posted on 10/04/2026 7:00:32 AM PDT by escapefromboston (Peace, commerce and honest friendship with all nations, entangling alliances with none.)
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To: tired&retired

I have observed this same memory loss in people who go through a profound spiritual experience that diminishes their ego identity. I joke that it’s as though the unavailable memories are stored in the basement while they are living in the attic.


20 posted on 10/04/2026 7:00:34 AM PDT by tired&retired (Blessings )
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