Posted on 05/06/2024 8:59:41 PM PDT by Jyotishi
London -- A team of scientists from the world’s leading universities have developed a new all-in-one vaccine that they hope can protect humans against a broad range of coronaviruses, including ones that are yet to emerge.
The research published in ‘Nature Nanotechnology’ on Monday is based on a new approach to vaccine development called “proactive vaccinology”, where scientists build a vaccine before the disease-causing pathogen even emerges, which has shown promising results in mice.
The study by the Universities of Oxford and Cambridge in the UK and Caltech in the US says the vaccine works by training the body’s immune system to recognise specific regions of eight different coronaviruses, including SARS-CoV-2 which caused the COVID-19 outbreak, and several that are currently circulating in bats and have potential to jump to humans and cause a pandemic. “Our focus is to create a vaccine that will protect us against the next coronavirus pandemic, and have it ready before the pandemic has even started,” said Rory Hills, a graduate researcher in the University of Cambridge’s Department of Pharmacology and first author of the report.
For example, the new vaccine does not include the SARS-CoV-1 coronavirus, which caused the 2003 SARS outbreak, yet it still induces an immune response to that virus. “We’ve created a vaccine that provides protection against a broad range of different coronaviruses – including ones we don’t even know about yet,” said Hills.
Key to its effectiveness is that the specific virus regions the vaccine targets also appear in many related coronaviruses. By training the immune system to attack these regions, it gives protection against other coronaviruses not represented in the vaccine, including ones that haven’t even been identified yet.
“We don’t have to wait for new coronaviruses to emerge. We know enough about coronaviruses, and different immune responses to them, that we can get going with building protective vaccines against unknown coronaviruses now,” said Professor Mark Howarth in the University of Cambridge’s Department of Pharmacology, senior author of the report.
“Scientists did a great job in quickly producing an extremely effective COVID vaccine during the last pandemic, but the world still had a massive crisis with a huge number of deaths. We need to work out how we can do even better than that in the future, and a powerful component of that is starting to build the vaccines in advance,” he said.
The new ‘Quartet Nanocage’ vaccine is based on a structure called a nanoparticle – a ball of proteins held together by incredibly strong interactions. Chains of different viral antigens are attached to this nanoparticle using a novel “protein superglue”. Multiple antigens are included in these chains, which trains the immune system to target specific regions shared across a broad range of coronaviruses. The latest study demonstrated that the new vaccine raises a broad immune response, even in mice that were pre-immunised with SARS-CoV-2. The new vaccine is much simpler in design than other broadly protective vaccines currently in development, which the researchers believe should accelerate its route into clinical trials.
The underlying technology that the scientific collaboration has developed also has potential for use in vaccine development to protect against many other health challenges. It is said to improve on previous work, by the Oxford and Caltech groups, to develop a novel all-in-one vaccine against coronavirus threats.
According to experts, conventional vaccines include a single antigen to train the immune system to target a single specific virus, which may not protect against a diverse range of existing coronaviruses or against pathogens that are newly emerging.
The latest research was funded by the UK’s Biotechnology and Biological Sciences Research Council.
I’ll just stick with natural immunity.
I think around $12 the last I bought some.
I just looked. Down to $11 for the Durvet apple flavored at a nearby TSC.
If I get vaccinated twice, can I vote twice?
>> If I get vaccinated twice, can I vote twice?
Heh. Nice try.
(Of course you can! Pass it along...)
If I get vaccinated twice, can I vote twice?
<>
Yes, but it can only be for Biden.
Or we could imitate Sweden.
[New vaccine may be effective against all coronaviruses]
Just ONE more jab. We promise.
Just ONE more. Really.
No. We’re serious this time.
Just ONE more jab. C’mon.
Just ONE more.
Refused the first one...and almost got fired. Quite a few people in the Hosp. I worked at refused....Small Hosp. So I figure they didn’t want to lose people.
Extremely effective in killing and hurting people...!!!!!
AJ had a good show today about how cancer is exploding due to the jab.
The nano bugs may decide to eat you if there is no COVID. You could be the first to be eaten by the cure.
So, get Covid before getting the vaccine? Majes perfect sense.
“I’ll just stick with natural immunity.”
Be careful, they may make it illegal to rely on natural immunity.
From leading universities, eh! Well then, let me just run right into line!!! Lol!
com’on man! Just let me put the tip in!
let’s have them study it’s effects for 15 or 20 years on these researchers and on members of the “UK’s Biotechnology and Biological Sciences Research Council.”
then get back to me after we all see how they do.
“may be” is just a way of saying, “Let’s find out”
“I wonder why nature suddenly decided we needed a bunch of new sars- corona viri?”
Maybe scientists have improved their ability to detect them.
I don’t think so...
“Scientists did a great job in quickly producing an extremely effective COVID vaccine during the last pandemic”
This publication is garbage.
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