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Ab8 COVID-19 Drug Breakthrough: Tiny Antibody Component Completely Neutralizes the SARS-CoV-2 Virus
Science tech daily ^ | Today | University of Pittsburgh

Posted on 09/14/2020 6:22:55 AM PDT by cba123

University of Pittsburgh School of Medicine scientists have isolated the smallest biological molecule to date that completely and specifically neutralizes the SARS-CoV-2 virus, which is the cause of COVID-19. This antibody component, which is 10 times smaller than a full-sized antibody, has been used to construct a drug — known as Ab8 — for potential use as a therapeutic and prophylactic against SARS-CoV-2.

The researchers report today (September 14, 2020) in the journal Cell that Ab8 is highly effective in preventing and treating SARS-CoV-2 infection in mice and hamsters. Its tiny size not only increases its potential for diffusion in tissues to better neutralize the virus, but also makes it possible to administer the drug by alternative routes, including inhalation. Importantly, it does not bind to human cells — a good sign that it won’t have negative side-effects in people.

Ab8 was evaluated in conjunction with scientists from the University of North Carolina at Chapel Hill (UNC) and University of Texas Medical Branch (UTMB) at Galveston, as well as the University of British Columbia and University of Saskatchewan.

“Ab8 not only has potential as therapy for COVID-19, but it also could be used to keep people from getting SARS-CoV-2 infections,” said co-author John Mellors, M.D., chief of the Division of Infectious Diseases at UPMC and Pitt. “Antibodies of larger size have worked against other infectious diseases and have been well tolerated, giving us hope that it could be an effective treatment for patients with COVID-19 and for protection of those who have never had the infection and are not immune.”

(Excerpt) Read more at scitechdaily.com ...


TOPICS: Business/Economy; Foreign Affairs; News/Current Events
KEYWORDS: ab8; bioweapon; covid; kungflu
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See the full article...

Seems rather significant.

1 posted on 09/14/2020 6:22:55 AM PDT by cba123
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To: cba123

25 years out after tests


2 posted on 09/14/2020 6:24:37 AM PDT by devane617 (Kyrie Eleison, where I'm going, will you follow?)
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To: cba123

https://scitechdaily.com/ab8-covid-19-drug-breakthrough-tiny-antibody-component-completely-neutralizes-the-sars-cov-2-virus/


3 posted on 09/14/2020 6:24:54 AM PDT by cba123 ( Toi la nguoi My. Toi bay gio o Viet Nam)
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To: cba123

"administer the drug by alternative routes, including inhalation."

YUGE!!!! : Think: Mouth Spray!

4 posted on 09/14/2020 6:26:09 AM PDT by LibFreeUSA
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To: cba123

Oh. This seems remarkable. I hope human double blind studies are started soon.


5 posted on 09/14/2020 6:26:21 AM PDT by hawkaw
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To: cba123

Fascinating, and if this works, an absolute game changer!


6 posted on 09/14/2020 6:29:36 AM PDT by Shady (It is the rule of law vs tyranny, plain and simple, and it is the fight of our lives...)
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To: cba123

Good news............for mice and hamsters.................


7 posted on 09/14/2020 6:30:03 AM PDT by Red Badger (Sine Q-Anon.....................very............)
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To: Shady

8 posted on 09/14/2020 6:32:37 AM PDT by Red Badger (Sine Q-Anon.....................very............)
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To: Red Badger

lol


9 posted on 09/14/2020 6:34:51 AM PDT by dp0622 (I DON'T KNOW WHAT TO DO ABO UT THE COVID GODFATHER, I DON'T KNOW WHAT TO DO. YOU CAN ACT LIKE A MAN!)
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To: cba123

This is just more “high tech” we’ve gleaned from the contents of crashed UFO’s at area 51. ;)


10 posted on 09/14/2020 6:42:45 AM PDT by cuban leaf (The political war playing out in every country now: Globalists vs Nationalists)
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To: cba123

I wonder if this is the sort of thing that a virus rapidly mutates away from being affected by, even if it works at first.

And, then time to market is a big issue.


11 posted on 09/14/2020 6:43:53 AM PDT by Pearls Before Swine
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To: cba123

Without a double blind study this information is useless.


12 posted on 09/14/2020 6:49:59 AM PDT by pas
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To: pas

It’s science

IT talks about molecules and stuff.

Therefore, it must not be believed


13 posted on 09/14/2020 6:52:14 AM PDT by bert ( (KE. NP. N.C. +12) Progressives are existential American enemies.....all of them)
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To: Pearls Before Swine

I don’t know.

I just searched online, it appears this story is very, very new.

Like I found exactly one earlier story, like 15 minutes earlier.

Just the two stories, thus far, possibly?


14 posted on 09/14/2020 6:53:03 AM PDT by cba123 ( Toi la nguoi My. Toi bay gio o Viet Nam)
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To: cba123

15 posted on 09/14/2020 6:53:26 AM PDT by Hatteras
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To: cba123

Back in May there was an odd Murder-Suicide at Pitt involving a coronavirus researcher. Bing Liu was a University of Pittsburgh researcher was said to have been on the verge of making “significant findings” in his work.

Sounds like the murder-suicide didn’t stop the progress.


16 posted on 09/14/2020 6:53:50 AM PDT by ClearCase_guy (If White Privilege is real, why did Elizabeth Warren lie about being an Indian?)
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To: cba123

Tiny, eh? What if we shrunk down some aquanauts, injected them in a teeny, tiny submarine into the blood stream and let them duke it out with the virus? Sounds like a great albeit familiar script.


17 posted on 09/14/2020 6:59:11 AM PDT by NonValueAdded ("Sorry, your race card has been declined. Can you present any other form of argument?")
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To: NonValueAdded
Tiny, eh? What if we shrunk down some aquanauts, injected them in a teeny, tiny submarine into the blood stream and let them duke it out with the virus? Sounds like a great albeit familiar script.

Already there are pill sized cameras that are swallowed and transmit images to a recorder via cable leads much like EKG wires. Next on deck will be multi-purpose virus killing nanobots...which for cinematic purposes could appear as nano-Transformers lead by Nano-Optimus Prime....;>)

In NANO Space you can't hear the Screams.

18 posted on 09/14/2020 7:12:26 AM PDT by Covenantor (We are ruled...by liars who refuse them news, and by fools who can not govern. " Chesterton)
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To: Red Badger
Remember this?


19 posted on 09/14/2020 7:16:44 AM PDT by HangnJudge
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To: cba123

I didn’t expect you, or anyone for that matter, to know yet.

But I asked what I thought was a logical question before getting totall excited.


20 posted on 09/14/2020 7:57:14 AM PDT by Pearls Before Swine
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