Posted on 04/09/2019 10:09:35 PM PDT by bkopto
AFTER decades of disappointment, we may have a new lead on fighting Alzheimer’s disease. Compelling evidence that the condition is caused by a bacterium involved in gum disease could prove a game-changer...
Now researchers from Cortexyme and several universities have reported finding the two toxic enzymes that P. gingivalis uses to feed on human tissue in 99 and 96 per cent of 54 human Alzheimer’s brain samples taken from the hippocampus – a brain area important for memory (Science Advances, doi.org/gftvdt). These protein-degrading enzymes are called gingipains, and they were found in higher levels in brain tissue that also had more tau fragments and thus more cognitive decline.
The team also found genetic material from P. gingivalis in the cerebral cortex – a region involved in conceptual thinking – in all three Alzheimer’s brains they looked for it in.
“This is the first report showing P. gingivalis DNA in human brains, and the associated gingipains co-localising with plaques,” says Sim Singhrao at the University of Central Lancashire, UK, who wasn’t involved in the study. Her team has previously found that P. gingivalis actively invades the brains of mice with gum infections.
When Lynch and her colleagues looked at brain samples from people without Alzheimer’s, they saw that some had P. gingivalis and protein accumulations, but at low levels. We already know that amyloid and tau can accumulate in the brain for 10 or 20 years before Alzheimer’s symptoms begin. This, says the team, shows that P. gingivalis doesn’t get into the brain as a result of Alzheimer’s – but could be the cause.
Although there is plenty you can do to reduce your risk of gum disease, Cortexyme is hoping it can stop or even reverse Alzheimer’s using molecules it has developed that block gingipains.
(Excerpt) Read more at newscientist.com ...
And floss, floss, floss. That’s key for gum health.
Do not get root canals. This is how your life ending mouth bacteria spread throughout the body, particularly the heart, arteries, and brain. It gets in the blood suplies from the tooth into the jaw and down your neck into the heart and other organs.
Heart disease patients have detrimental/damaging mouth bacteria in the heart muscle.
I’m scheduled for my first root canal soon. What’s the alternative?
Wear a compression bandage on the head.
And yet people who were very sharp until the day they died had a LOT of plaque in their brains upon autopsy.
IIRC there were more than a few folks who had this anomaly
Could be a combination of factors, this being one.
I used to know what caused it. But I forgot. I think I wrote it down somewhere...
There’s a movie/documentary called “Root Cause” that tells of one man’s experience. Options are discussed there. Movie is rentable for 99 cents on Apple TV or the iTunes Store.
I am not a dentist and not giving any advice. Do your own research. Discuss with your own dentist.
There’s a movie/documentary called “Root Cause” that tells of one man’s experience. Options are discussed there. Movie is rentable for 99 cents on Apple TV or the iTunes Store.
I am not a dentist and not giving any advice. Do your own research. Discuss with your own dentist.
Pinging you. I’ve seen you talk about this before.
Oops. My response to your post was post was meant for Post 5. Sorry.
Oh great news.
I don’t believe it! If true there would be practically zero cases of Atzheimer’s here in Alabama. You know, we have no teeth.
Looks similar to the prions of mad cow disease.
With your current dentist they may not offer an alternative.
There are some dentists that try to do what they can to save the tooth. I dont know the current state of your tooth so i cant say what options would work for you.
But most dentists are conventional and drill and fill and pull. Some get more schooling and learn other techniques to do minimal invasive and destructive dentistry, to preserve as much of the tooth as they can, using lasers, smaller fillings instead of way oversized ones that weaken the tooth structure, use non mercury filings, glass resins or other resins that are more like natural tooth structure.
I’m scheduled for my first root canal soon. What’s the alternative?
**********************************************
Have the infected tooth extracted and let your remaining teeth shift position. Or just don’t do anything and let it fester and risk dying a premature death caused by an untreated infection as Jim Henson of the Muppets did.
I wonder if this mouth bacteria is responsible for Diabetes. An expert in Diabetes revealed to me tonight that dimentia is actually Type 3 Diabetes in the brain. The nerve cells have developed insulin resistance from some source of inflammation. Now we may have the source of that inflammation.
Disclaimer: Opinions posted on Free Republic are those of the individual posters and do not necessarily represent the opinion of Free Republic or its management. All materials posted herein are protected by copyright law and the exemption for fair use of copyrighted works.
