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Doctor treats Ebola with HIV drug in Liberia — seemingly successfully
CNN Health ^ | September 25, 2014 | Elizabeth Cohen

Posted on 10/03/2014 1:43:14 PM PDT by RinaseaofDs

Dr. Gorbee Logan has given the drug, lamivudine, to 15 Ebola patients, and all but two survived. That's about a 13% mortality rate.

Logan said he got the idea to try lamivudine when he read in scientific journals that HIV and Ebola replicate inside the body in much the same way.

"Ebola is a brainchild of HIV," he said. "It's a destructive strain of HIV."

At first he tried a drug called acyclovir, which is often given to HIV patients to treat infections that occur with their weakened immune systems. But it didn't seem to be effective. Then he tried lamivudine on a health care worker who'd become ill, and within a day or two he showed signs of improvement and survived.

Dr. Anthony Fauci, director of the National Institute of Allergy and Infectious Diseases says that theoretically, Logan's approach has some merit. Lamivudine is a nucleocide analog, and other drugs in this class are being studied to treat Ebola.

(Excerpt) Read more at cnn.com ...


TOPICS: News/Current Events
KEYWORDS: ebola; ebolatreatment; fauci; hivdrug; lamivudine; logan
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To: RinaseaofDs

RE: It is a destructive strain of HIV

Not even close. The guy is a quack. It would be great if he found something that slams this virus, but a tiny sample of 13 patients is meaningless.


21 posted on 10/03/2014 2:07:12 PM PDT by Missouri gal
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To: RinaseaofDs

Good grief this is fantastic! This could be an answer for so many if caught early.

Interesting relationship between HIV and Ebola too. .


22 posted on 10/03/2014 2:07:46 PM PDT by SE Mom (Proud mom of an Iraq war combat vet)
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To: Missouri gal

He’s a quack, except to say that 13 people who are alive that would not be.


23 posted on 10/03/2014 2:08:30 PM PDT by RinaseaofDs
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To: Missouri gal

13 is greater than the number that received ZMapp.

And a close analogue of this compound has been shown to arrest ebola in the lab.


24 posted on 10/03/2014 2:09:04 PM PDT by Black Agnes
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To: RinaseaofDs
Very good news!
25 posted on 10/03/2014 2:10:10 PM PDT by Chgogal (Obama "hung the SEALs out to dry, basically exposed them like a set of dog balls..." CMH)
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To: Chgogal

It’s not good news. Nobody at Fedzilla cares. They are sending 1000 more troops this week, and they are pushing a Zmapp drug that may or may not be as effective as something that has already passed FDA approval for HepB and HIV.

This guy does a VERY limited study, throws a Hail Mary, and touchdown.

It’s not like they flew people in immediately to study it, or treat another cohort of patients with it to see what would happen.

Nothing happened. Fauci MIGHT look into it.


26 posted on 10/03/2014 2:13:02 PM PDT by RinaseaofDs
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To: petercooper

The acyclovir is an anti fungal and it did not respond to that.


27 posted on 10/03/2014 2:13:23 PM PDT by Sequoyah101 (In God's eyes there is no collateral damage.)
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To: RinaseaofDs

It’s off patent.

There’s no money to be made from it.


28 posted on 10/03/2014 2:14:26 PM PDT by Black Agnes
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To: Black Agnes
It’s off patent. There’s no money to be made from it.

So pay for it out of Obola's stash. He's into throwing around Billions of other people's money like it ain't no thang.

29 posted on 10/03/2014 2:20:28 PM PDT by Windflier (To anger a conservative, tell him a lie. To anger a liberal, tell him the truth.)
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To: Windflier

That’s the point. Nobody gonna get rich sellin’ this.

It ain’t gonna fill nobody’s stash wid da money.


30 posted on 10/03/2014 2:21:31 PM PDT by Black Agnes
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To: Black Agnes

“There’s no money to be made from it.”

And if that’s the reason this isn’t deployed on an investigational basis in the next 48 hours, then someone should go to jail.

Monkeying with something like this for profit, and letting thousands die, is about the nearest thing I can call a ‘Crime Against Humanity’ that I can think of.


31 posted on 10/03/2014 2:22:47 PM PDT by RinaseaofDs
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To: RinaseaofDs

“Democrats are screaming for money and crying poor mouth about being all out of Zmapp.”

...and screaming in various articles I’ve been reading that it’s the Republican’s fault due budget cuts.

I smell a RAT here in that the political advantage of blaming the Republicans for creating a shortage of Zmapp could be compromised IF this story gets out, as well it would deter the release of funding for all the would be hero’s on the Left who would Solyndra the R. & D. of new drugs.

Once the money is released from the control of the government it’s open house as it’s sidetracked to many different pockets in the process of achieving unaccountable, and “over budget”.

Yeah this is a story the Left would have preferred CNN NOT have exposed.


32 posted on 10/03/2014 2:25:13 PM PDT by rockinqsranch ((Dems, Libs, Socialists, call 'em what you will. They ALL have fairies livin' in their trees.))
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To: RinaseaofDs

bkmk


33 posted on 10/03/2014 2:27:24 PM PDT by Sergio (An object at rest cannot be stopped! - The Evil Midnight Bomber What Bombs at Midnight)
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To: Black Agnes
Nobody gonna get rich sellin’ this. It ain’t gonna fill nobody’s stash wid da money.

I dunno. Seems to me that natural market forces would dictate that if you've got something that is rare, and is highly sought after by a desperate customer base, you're gonna make money selling it.

How much would you be willing to pay for a dose of this drug, if your kid just came down with the symptoms for Ebola? I'll bet (like me) you'd pay whatever it cost.

Aspirin is 'off patent' too, but billions of tablets are sold every year for a profit.

34 posted on 10/03/2014 2:27:25 PM PDT by Windflier (To anger a conservative, tell him a lie. To anger a liberal, tell him the truth.)
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To: Windflier

Aspirin isn’t the profit center that Gardasil is however.


35 posted on 10/03/2014 2:28:32 PM PDT by Black Agnes
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To: RinaseaofDs
If a returning Japanese citizen develops EVD we will see a human trial of favipiravir within about 10 minutes.

T-705 suppressed replication of Zaire EBOV in cell culture by 4 log units with an IC90 of 110 μM (animal model)

36 posted on 10/03/2014 2:33:18 PM PDT by steve86 (Prophecies of Maelmhaedhoc OÂ’Morgair (Latin form: Malachy))
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To: Windflier; Black Agnes

I dunno. Seems to me that natural market forces would dictate that if you’ve got something that is rare, and is highly sought after by a desperate customer base, you’re gonna make money selling it.

How much would you be willing to pay for a dose of this drug, if your kid just came down with the symptoms for Ebola? I’ll bet (like me) you’d pay whatever it cost.

Aspirin is ‘off patent’ too, but billions of tablets are sold every year for a profit.

*********************************************************

Market forces do prevail. Aspirin - Billions of tablets at a small price - lots of people want it and can afford it. Lots of dollars to be made even if they clear just a small amount on each tablet.

Drugs needed for just a few people - yes the people will want to pay whatever it takes, but that’s got a limitation built in as to what they could actually manage to scrape together.

Unless a person’s Insurance covers it, or they are rich, or they steal the money etc, there will be a price beyond which they won’t be able to pay.

The manufacturer will have a pro forma analysis that shows the volume they will need to sell to make a profit. If that volume is not there, they quit making it. Sometimes they keep it going by making it in China or somewhere with less costs.

If it cost a million dollars to make the drug and there’s only 5 people desperate for it, just as an example, then the patients will need to be very rich indeed.

The market determines it all.


37 posted on 10/03/2014 2:40:21 PM PDT by greeneyes (Moderation in defense of your country is NO virtue. Let Freedom Ring.)
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To: RinaseaofDs

Someone tell Dr. Oz. He might actually get the news out. I have read that he has had some programs lately on the Ebola situation.


38 posted on 10/03/2014 2:44:19 PM PDT by greeneyes (Moderation in defense of your country is NO virtue. Let Freedom Ring.)
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To: steve86

No doubt.

China has a small molecule in production now as well:

http://us.india.com/news/world/chinas-first-anti-ebola-drug-jk-05-approved-for-production-133694/

If this isn’t ripped off favipiravir or lamivudine, it’s likely a close structural analog.


39 posted on 10/03/2014 2:44:44 PM PDT by Black Agnes
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To: RinaseaofDs

A few years back they said that HIV/AIDS was caused by having sex with monkeys. the other day I read that Ebola was caused my eating monkey meat. I think people should leave the monkeys alone!


40 posted on 10/03/2014 3:01:45 PM PDT by jrd
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