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Drug Appears To Work For Weight-Loss In U-M Study
CBS News ^ | July 1, 2013 | NA

Posted on 07/01/2013 8:18:52 PM PDT by neverdem


Obese mice were given the drug Amlexanox lost weight. (credit: University of Michigan)

ANN ARBOR (WWJ) - Could a drug used to treat canker sores be a miracle weight-loss solution? Researchers at University of Michigan are working to find out.

Back in February, U-M researchers discovered that mice given the prescription drug, Amlexanox, lost weight without diet or exercise.

Now, Dr. Elif Oral, an associate professor of internal medicine at U-M’s Metabolism, Endocrinology & Diabetes (MEND) division, is beginning the first human study to determine whether the drug will have the same effect in people.

“The weight loss together in improved glucose metabolism makes this even more interesting, you know, and more exciting,” Oral told WWJ Health Reporter Sean Lee. “We’re going to start out by targeting the diabetic population because that’s the population that needs more immediate help.”

The study is small, enrolling just 10 obese people with Type 2 diabetes. If that goes well, the next study will enroll more people.

For more information about volunteering, call 734-615-0539 or visit this link.


TOPICS: Culture/Society; News/Current Events
KEYWORDS: amlexanox; cankersores; diabetes; obesity; type2diabetes; weight; weightloss
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1 posted on 07/01/2013 8:18:52 PM PDT by neverdem
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To: neverdem

Know what really works like a charm for weight loss? Exercising and eating less. It’s the magic formula. I lost 22 lbs in four months that way.


2 posted on 07/01/2013 8:23:51 PM PDT by GreatRoad (O < 0)
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To: austinmark; FreedomCalls; IslandJeff; JRochelle; MarMema; Txsleuth; Newtoidaho; texas booster; ...
An inhibitor of the protein kinases TBK1 and IKK-ɛ improves obesity-related metabolic dysfunctions in mice.

FReepmail me if you want on or off the diabetes ping list.

3 posted on 07/01/2013 8:24:00 PM PDT by neverdem (Register pressure cookers! /s)
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To: cripplecreek

Ann Arbor is looking for recruits.


4 posted on 07/01/2013 8:27:06 PM PDT by neverdem (Register pressure cookers! /s)
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To: GreatRoad

radiation and chemo also work.


5 posted on 07/01/2013 8:29:15 PM PDT by RitchieAprile
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To: RitchieAprile

Sorry.


6 posted on 07/01/2013 8:30:44 PM PDT by doc1019 (There is absolutely no difference between pro-choice and pro-abortion.)
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To: neverdem

The problem is inactivity and overeating. Diet and processed foods are a huge problem. But if this is a disease, it’s caused by consumerism and federal welfare.

Back in the early 90’s I worked at Safeway. Mothers brought in WIC cards for milk. People paid for foodstuffs with paper food stamps. There was a built-in humility that made people want to avoid the situation.

It’s the same humility that could have held single parenthood in check. Well, if no-fault divorce wasn’t possible.


7 posted on 07/01/2013 8:30:46 PM PDT by andyk (I have sworn...eternal hostility against every form of tyranny over the mind of man.)
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To: RitchieAprile

I’m really sorry.


8 posted on 07/01/2013 8:35:50 PM PDT by andyk (I have sworn...eternal hostility against every form of tyranny over the mind of man.)
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To: Spunky

Ping to self for later reading.


9 posted on 07/01/2013 8:36:48 PM PDT by Spunky
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To: GreatRoad

Just eating less works too. I’ve done it . no exercise. I know the media is pushing the exercise thing.


10 posted on 07/01/2013 8:40:18 PM PDT by Democrat_media (IRS rigged election for Obama and democrats by shutting down tea party)
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To: GreatRoad
Know what really works like a charm for weight loss?

Exlax and prune juice?

11 posted on 07/01/2013 8:54:29 PM PDT by umgud (2A can't survive dem majorities)
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To: GreatRoad

“Exercising and eating less. It’s the magic formula.”

Yup...works every time...and when they tell you it does not work, they are lying...


12 posted on 07/01/2013 9:01:26 PM PDT by GGpaX4DumpedTea (I am a Tea Party descendant...steeped in the Constitutional Republic given to us by the Founders)
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To: RitchieAprile
radiation and chemo also work.

So does stress, grief and worry.

Eating comes to a complete stop.

13 posted on 07/01/2013 9:04:35 PM PDT by Lizavetta (You get what you tolerate)
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To: neverdem

I’ve lost exactly 40 pounds since the first of the year ( started at 222 and now I am 182 ). My secret ? I gave up beer and soda and stopped stuffing my face with food. I don’t exactly eat healthy but just eat less than I used to. I make better choices for sure. Instead of a Big Mac I just get a plain cheeseburger. Instead of the honey bun for breakfast I choose a granola cereal and some yogurt. Simple stuff... It’s made a huge difference and the weight is still coming off !


14 posted on 07/01/2013 9:54:16 PM PDT by Bud Krieger (Another President , another idiot......)
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To: GreatRoad
Know what really works like a charm for weight loss? Exercising and eating less. It’s the magic formula. I lost 22 lbs in four months that way.

I tried that and actually made some good progress until I plateaued. Then I went to a low-carb diet and immediately started losing again. Whatever the case, once you hit a certain age and a certain level of weight gain, exercise alone doesn't cut it; you've got to lower the caloric intake as well.

15 posted on 07/01/2013 10:09:49 PM PDT by Mr Ramsbotham (Laws against sodomy are honored in the breech.)
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To: GGpaX4DumpedTea
This works well too.


16 posted on 07/01/2013 10:46:24 PM PDT by itsahoot (It is not so much that history repeats, but that human nature does not change.)
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To: itsahoot

Divorce works well.


17 posted on 07/01/2013 11:00:08 PM PDT by jb257mag
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To: neverdem

Thinner......


18 posted on 07/01/2013 11:01:39 PM PDT by Smokin' Joe (How often God must weep at humans' folly. Stand fast. God knows what He is doing)
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To: jb257mag

Specially if you drink a lot and forget to eat while you are chasing replacements.


19 posted on 07/01/2013 11:09:35 PM PDT by itsahoot (It is not so much that history repeats, but that human nature does not change.)
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To: GreatRoad

Another miracle cure we’ll never hear of again.


20 posted on 07/01/2013 11:17:35 PM PDT by daler
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