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New Take on a Prostate Drug, and a New Debate
NY Times ^ | June 15, 2008 | GINA KOLATA

Posted on 06/15/2008 12:13:26 AM PDT by neverdem

For the first time, leading prostate cancer specialists say, they have a drug that can significantly cut men’s risk of developing the disease, dropping the incidence by 30 percent.

But the discovery, arising from a new analysis of a large federal study, comes with a debate: Should men take the drug?

Prostate cancer is unlike any other because it is relatively slow-growing and while it can kill, it often is not lethal. In fact, most leading specialists say, a major problem is that men are getting screened, discovering they have cancers that may or may not be dangerous, and opting for treatments that can leave them impotent or incontinent.

So should healthy men take a drug for the rest of their lives to avoid getting and being treated for a cancer that, most often, would be better off undiscovered and untreated? Is it worth risking a chance that unanticipated side effects may emerge years later if millions of men with no prostate problems take the drug?

Some prostate...

--snip--

It took years, but the analysis showed the hypothesis was right. Now, two groups of independent researchers conclude, in papers in the current issue of Cancer Prevention Research, that finasteride decreases the risk of having any tumor at all — large or small, fast growing or slow growing, by the same amount — nearly 30 percent.

With this new analysis, many prostate cancer specialists, including Dr. Scardino, say their view of the drug has completely changed. The study actually found that finasteride protects against both lethal and less dangerous tumors and could cut prostate cancer risk by nearly a third.

Even the effect on smaller tumors has important implications, said Dr. , Jr., the study’s principal researcher and a urologist at the University of Texas Health Science Center in San Antonio...

(Excerpt) Read more at nytimes.com ...


TOPICS: Culture/Society; News/Current Events
KEYWORDS: finasteride; health; medicine; prostatecancer
Does the level of prostate cancer risk affect cancer prevention with finasteride?

That study is from Urology, not Cancer Prevention Research.

1 posted on 06/15/2008 12:13:27 AM PDT by neverdem
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To: neverdem

Perhaps God is smiling down on balding men, afterall. :)


2 posted on 06/15/2008 12:52:05 AM PDT by CaspersGh0sts
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To: CaspersGh0sts

I dunno. I’m bald and I’m waiting to see if I have prostate cancer.


3 posted on 06/15/2008 1:23:49 AM PDT by Luke21
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To: neverdem

If this drug cut breast cancer by 30%, there would be no problem. It would be universally available to all women.

Men get second rate health care, so of course there is a big debate by the democrats and their crooked health insurer allies as to availability.

Well, we are not in Canada or the UK, yet. So to all the government micromanagers, go to ****!.


4 posted on 06/15/2008 1:28:14 AM PDT by FormerACLUmember (When the past no longer illuminates the future, the spirit walks in darkness.)
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To: Luke21

“I dunno. I’m bald and I’m waiting to see if I have prostate cancer.”

I wish you the best, and God bless.

The reason I brought it up is that finasteride is the generic name of Propecia, which is the single most effective means of preventing, stopping, or slowing balding in men. You have to take it over the course of a lifetime, or eventually you will start losing ground again.

I guess if you’re cursed with having to deal with balding, you may not have to deal with prostate cancer or benign prostate englargement in the future.


5 posted on 06/15/2008 1:42:34 AM PDT by CaspersGh0sts
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To: neverdem
I'm 45 and was diagnosed with prostate cancer last week. I'm wondering if there are any others out there who are roughly my age who have received the same diagnosis. My urologist says that the only option for me is to have surgery to have it removed. He said it was caught early and that there is a 95% chance for recovery. I plan on getting a second opinion. Just looking for advice from anyone who has been through this.
6 posted on 06/15/2008 4:07:34 AM PDT by RU88 (The false messiah can not change water into wine any more than he can get unity from diversity.)
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To: RU88

Get a second opinion.

My father had these little radioactive seeds put in for a few weeks and it’s all gone.

I am going for a biopsy for the same thing next week.

Lots of other options.


7 posted on 06/15/2008 4:25:55 AM PDT by ChiefKujo
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To: RU88

....I’m a bit older than you and have had a number of friends who have gone thru this....they are all still alive and kicking....and they all did exactly what you’re planning to do: they got second/third doctors opinions and also checked out multiple clinics that specialize in men’s prostate health....there’s so much more available out there that the odds are really shifting in our favor ....I’m sending you and your family a Sunday morning prayer right now.


8 posted on 06/15/2008 4:33:54 AM PDT by STONEWALLS
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To: STONEWALLS

Thank you. I truly appreciate that.


9 posted on 06/15/2008 4:40:28 AM PDT by RU88 (The false messiah can not change water into wine any more than he can get unity from diversity.)
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To: RU88

Even if you opt for surgery, do some investigation. I have a friend about your age that had his removed with a robotic assisted surgical technique and he claims that, after the recovery, he has no side effects. His oncologist is associated with the Dana Farber cancer center in Boston.

Good luck to you


10 posted on 06/15/2008 5:13:11 AM PDT by muir_redwoods (Free Sirhan Sirhan, after all, the bastard who killed Mary Jo Kopechne is walking around free)
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To: FormerACLUmember

Well, as someone who has worked in medicine for a while, I can say there is a germ of truth to this.

I repeatedly hear comments made by a wide spectrum of women that if some medical condition with no cure that disproportionally affects women affected men instead, there would be a cure for it tomorrow.

But we all know from experience with whites and racism, only men are capable of sexism. /s


11 posted on 06/15/2008 5:56:25 AM PDT by rlmorel (Clinging bitterly to Guns and God in Massachusetts...:)
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To: neverdem

prostate ping, for later reading.....


12 posted on 06/15/2008 6:19:27 AM PDT by gitmogrunt
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To: gitmogrunt

Bump


13 posted on 06/15/2008 7:24:26 AM PDT by painter (If you like $4/gal, Thank Congress!)
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To: rlmorel; FormerACLUmember
I repeatedly hear comments made by a wide spectrum of women that if some medical condition with no cure that disproportionally affects women affected men instead, there would be a cure for it tomorrow.

But we all know from experience with whites and racism, only men are capable of sexism. /s

LOL! Didn't Senator Al D'mato put breast cancer research funding in a Defense Dept. authorization or appropriation bill?

14 posted on 06/15/2008 11:43:55 AM PDT by neverdem (I'm praying for a Divine Intervention.)
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To: RU88
Even if you get a second opinion, you're still in a bind. Guess what urologists do besides consultations?

Check nerve sparing prostatectomy at PubMed.

I'd start with review articles. Good luck!

15 posted on 06/15/2008 11:54:43 AM PDT by neverdem (I'm praying for a Divine Intervention.)
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To: El Gato; Ernest_at_the_Beach; Robert A. Cook, PE; lepton; LadyDoc; jb6; tiamat; PGalt; Dianna; ...
We may all be space aliens: study I don't know.

Deep-ocean vents are a source of oil and gas (evidence of abiogenic hydrocarbons) Carbon-13 is here too.

Therapy in China gives blind Ark. girl some sight

Therapy in China gives blind Ark. girl some sight

FReepmail me if you want on or off my health and science ping list.

16 posted on 06/15/2008 12:54:10 PM PDT by neverdem (I'm praying for a Divine Intervention.)
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To: El Gato; Ernest_at_the_Beach; Robert A. Cook, PE; lepton; LadyDoc; jb6; tiamat; PGalt; Dianna; ...
The Science of Gun Control

I goofed, obviously.

Homicide and Suicide Rates Associated With Implementation of the Brady Handgun Violence Prevention Act

That's my penance.

17 posted on 06/15/2008 1:22:21 PM PDT by neverdem (I'm praying for a Divine Intervention.)
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To: RU88

get an expert opinion before they cut.

Find an oncologist, a cancer specialist, preferably one who is in a university setting.

There are other treatments like radiation seeds.

We used to do prostatectomy operations for all cancer, but in the last ten years, things have changed...it’s been awhile since any of my patients has had surgery for the cancer...

lots of new treatments that cause less impotence.
But the medicines/chemo mean a rough year of treatment...


18 posted on 06/16/2008 4:22:28 PM PDT by LadyDoc (liberals only love politically correct poor people)
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