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You Are What Your Grandmother Ate
New Scientist ^ | 11-13-2006 | Roxanne Khamsi

Posted on 11/13/2006 3:06:19 PM PST by blam

You are what your grandmother ate 22:00 13 November 2006
NewScientist.com news service
Roxanne Khamsi

The mice on the left-hand side have active AVY genes, giving them golden fur, while those on the right have silenced AVY genes (Image: Cropley et al/PNAS)

A mother’s diet can change the behaviour of a specific gene for at least two subsequent generations, a new study demonstrates for the first time.

Feeding mice an enriched diet during pregnancy silenced a gene for light fur in their pups. And even though these pups ate a standard, un-enriched diet, the gene remained less active in their subsequent offspring.

The findings could help explain the curious results from recent studies of human populations – including one showing that the grandchildren of well-fed Swedes had a greater risk of diabetes.

The new mouse experiment lends support to the idea that we inherit not only our genes from our parents, but also a set of instructions that tell the genes when to become active. These instructions appear to be passed on through “epigenetic” changes to DNA – genes can be activated or silenced according to the chemical groups that are added onto them.

Gene silencer

David Martin at the Children’s Hospital Oakland Research Institute in California, US, and colleagues used a special strain of genetically identical mice with an overactive version of a gene that influences fur colour. Mice with the AVY version of this gene generally have golden fur.

(Excerpt) Read more at newscientist.com ...


TOPICS: News/Current Events
KEYWORDS: dna; genes; grandmother; offspring
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To: A. Pole

PUKS. Heritability of acquired atrtributes cannot be happening on lamarckian time scale, for that would require too fluid genetics. And genetics is reasonably resilient.


41 posted on 11/13/2006 5:15:57 PM PST by GSlob
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To: blam

Well I hope my grandmother had a good diet in TN during the civil war.


42 posted on 11/13/2006 5:16:06 PM PST by Modok
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To: EggsAckley

...I'm country eggs, farm fresh chickens, garden vegetables, raw milk & butter, cornbread, biscuits, homemade pork sausage, fresh wilted lettuce (in hot hog lard), coffee, iced tea, cocoanut cake, egg custard pie . .


43 posted on 11/13/2006 5:19:26 PM PST by Twinkie (GET BUSY, NANCY . . AL QAEDA IS EXPECTING A LOT FROM YOU!!)
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To: Oberon
I was wondering when you were going to show your I.D. If it matters to you, I approve.

I think that God created living beings, including man, through evolutionary process and in stages. As it is described in the Biblical story of Creation.

But I do not think that the Bible was intended to be read as biological handbook. Rather as a spiritual, mystical, moral and metaphysical text. So we need to read Bible with the right understanding and in right spirit.

On the other hand, God gave us the reason capable to explore the created world. I expect that the mechanism of evolution is as complex and elegant as biochemistry is or quantum physic. I reject crude and ugly the so called Darwinian/Jurassic Park paradigm (in which the inane random mutations are winnowed by imprecise selection) .

God is greater Artist than that. Science, if free to advance, might show us a little more about His skill.

44 posted on 11/13/2006 5:24:35 PM PST by A. Pole (Psalm 19: "The heavens declare the glory of God; and the firmament sheweth his handywork.")
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To: GourmetDan
Mainstream science takes another hit.

How, exactly?

45 posted on 11/13/2006 5:26:01 PM PST by Young Scholar
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To: A. Pole

Actually, with 21st century evolutionary biology that takes comparative genomics and other 21st century biology (e.g., epigenetics, micro-RNA) seriously, we are going to go WAY beyond both Darwin and Lamarck!!! We are now where physics was in 1900, just before Einstein and quantum mechanics.

This is a very long story, and I know what I am talking about. But it is too long a story for me to get into on a forum such as this.


46 posted on 11/13/2006 5:26:25 PM PST by Honorary Serb (Kosovo is Serbia! Free Srpska! Abolish ICTY!)
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To: GSlob
PUKS. Heritability of acquired atrtributes cannot be happening on lamarckian time scale, for that would require too fluid genetics. And genetics is reasonably resilient.

I am very eager to learn what you know about genetics proposed by Darwin.

47 posted on 11/13/2006 5:27:00 PM PST by A. Pole (Psalm 19: "The heavens declare the glory of God; and the firmament sheweth his handywork.")
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To: blam

Let's hope caviar and smoked salmon enrich my life.


48 posted on 11/13/2006 5:27:34 PM PST by Young Scholar
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To: Honorary Serb
with 21st century evolutionary biology [...] we are going to go WAY beyond both Darwin and Lamarck!!!

I agree completely! My point about "rehabilitation" of Lamarck, that he will be to some extent vindicated versus his so called Darwinian critics.

49 posted on 11/13/2006 5:30:00 PM PST by A. Pole (Psalm 19: "The heavens declare the glory of God; and the firmament sheweth his handywork.")
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To: agrarianlady
They consumed a George McGovern diet: plenty of hydrogenated oils (margarine was so preferable to butter, you know), corn, white bread, and pasta.

My grandparents were all immigrants. And they and assorted relatives switched to or ate this 'new' McGovern diet during the 60's & 70's. And it didn't do anything good for my grandmother's health. I remember the older relatives lamenting that after coming to America, the American born relatives were far less healthy (especially on my father's side), and they blamed the change in diet. Those who stuck to the 'old' ways longer, with healthy American additions, did better. My grandfather loved brown bread spread with a thick smear of lard. He lived to 92.

My grandmother loved raw onions. I can't eat them raw, or even partly cooked.

50 posted on 11/13/2006 5:32:17 PM PST by fortunecookie (My computer is fried, but I'm back with a temporary set up!)
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To: GourmetDan
" Mainstream science takes another hit.

Say What??

51 posted on 11/13/2006 5:51:08 PM PST by muir_redwoods (Free Sirhan Sirhan, after all, the bastard who killed Mary Jo Kopechne is walking around free)
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To: fortunecookie
My grandparents were farmers. In the spring, I have an overwhelming urge to plant a garden and work in the flower beds.

I wonder how that happened?

52 posted on 11/13/2006 5:54:06 PM PST by blam
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To: blam
The sins of the father will be visited on seven generations?!?

Well then, if food effects genetics what else might? It is well established that emotions/attitude effect hormone levels and immune response.

cause and effect isn't just for asians anymore =8-O

53 posted on 11/13/2006 5:56:31 PM PST by TigersEye (Ego chatters endlessly on. Mind speaks in great silence.)
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To: TigersEye
It is well established that emotions/attitude effect hormone levels and immune response.

Maybe there are biological/hormonal mechanisms of traits transfer AFTER the birth - pheromones might synchronize genetic switches or processing among close relatives?

54 posted on 11/13/2006 6:02:20 PM PST by A. Pole (Psalm 19: "The heavens declare the glory of God; and the firmament sheweth his handywork.")
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To: GourmetDan

Actually, to follow your logic, it was mainstream science backing up Biblical accuracy.


55 posted on 11/13/2006 6:06:41 PM PST by SuzyQue (Remember to think.)
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To: A. Pole
I'm sure that is a great possibility. The number of mechanisms in the physiology of a human being is astounding. Overlapping and redundant systems involving hormones, nervous system, pheromones, immune system and on and on each intricately tied with each other within the whole balancing internal changes with external stimuli!?! It is astounding.

If any chemical change can be shown to result in a genetically altered outcome in progenesis then a whole lot of things are on the table.

56 posted on 11/13/2006 6:35:17 PM PST by TigersEye (Ego chatters endlessly on. Mind speaks in great silence.)
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To: Twinkie; EggsAckley
"..I'm country eggs, farm fresh chickens, garden vegetables, raw milk & butter ..."

Wait - a - minute! I just checked, and Twinkies ain't got none of that stuff!

57 posted on 11/13/2006 7:21:51 PM PST by NicknamedBob (I propose a toast! "Here's to the Drive-By Media running out of gas!")
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To: Twinkie

--raw milk & butter--

Did it really tastes as good as I remember?


58 posted on 11/13/2006 8:25:24 PM PST by UpAllNight
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To: Carl LaFong
My grandmother baked cakes with the density of a nuetron star.I should have collapsed to the center of the earth by now.

LMAO! Well done.

59 posted on 11/13/2006 8:34:42 PM PST by Northern Alliance
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To: UpAllNight

I don't remember. I guess I was a little kid the last time I had raw milk. That was my grandmother.
Oh, I do remember the country butter; used to help my grandmother churn it - and it was good.


60 posted on 11/13/2006 9:22:10 PM PST by Twinkie (GET BUSY, NANCY . . AL QAEDA IS EXPECTING A LOT FROM YOU!!)
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