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Marrow stem cells defeat Alzheimers
UPI ^ | 02.17.06

Posted on 02/18/2006 3:32:17 PM PST by Coleus

MONTREAL, Feb. 17 (UPI) -- Canadian researchers said Friday they have uncovered a natural defense mechanism to Alzheimer's disease.

Not surprisingly, it involves stem cells -- those derived from bone marrow.

In Alzheimer's patients, plaque forms in the brain, but the brain's resident immune cells, called microglia, can't fight off the substance. The plaque can then kill off the brain's neurons, or nerve cells.

However, microglia harvested from bone marrow stem cells do appear capable of defeating the plague, said researchers from the Faculty of Medicine at Université Laval and the research centre at Centre hospitalier universitaire de Québec, Canada.

The researchers noted that, in transgenic mouse models of Alzheimer's, the bone marrow-derived microglia were specifically drawn to the amyloid proteins that form plague in the brains of Alzheimer's patients.

"The discovery ... is an important step towards a new therapeutic approach to Alzheimer's disease," states Rémi Quirion, scientific director of Canada's Institute of Neurosciences, Mental Health and Addiction (INMHA). "It is the perfect example of the potential social benefits of investing in health research," he said.

The Canadian scientists said that 280,000 Canadians aged 65 and over have Alzheimer's.


TOPICS: Canada; Culture/Society; Technical
KEYWORDS: adultstemcells; alzheimers; alzheimersdisease; amyloidproteins; bonemarrow; canada; microglia; montreal; plaque; stemcells
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Adult stem cells work there is NO need to harvest babies for their body parts.
 
To tell you the truth, I didn't think any kind of stem cell could cure an organic, whole-brain disease.  I would presume that if this process works on humans, it would benefit in the early stages or stop further progression, let's hope.  And killing babies for their parts is not the way, Ron Reagan, Jr., we mortal humans can't say who gets to live and who dies and whose life is more important, all life begins at conception and we have no right to experiment on children.
 
THE CODE FOR HUMAN LIFE

1 posted on 02/18/2006 3:32:18 PM PST by Coleus
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To: Coleus

This is outrageous to suggest it isn't necessary to tear apart human fetuses to get stem cells.


3 posted on 02/18/2006 3:37:03 PM PST by Paleo Conservative
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To: Coleus
This is particular great news for me...I have a pet mouse with Alzheimers.

No, seriously, this is big news. My grandmother had Alzheimers (and my mother was her caretaker)...overcoming Alzheimers is a big deal for millions of people.

Great post...thx.

4 posted on 02/18/2006 3:39:29 PM PST by Dark Skies ("Democracy is not the weapon of choice against islam...but free speech is!")
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To: Dark Skies

My grandmother also had Alzheimers.


5 posted on 02/18/2006 3:47:20 PM PST by Irish_Thatcherite (~~~A vote for Bertie Ahern is a vote for Gerry Adams!~~~)
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To: Coleus; wagglebee

That's good news!!


6 posted on 02/18/2006 3:49:11 PM PST by Irish_Thatcherite (~~~A vote for Bertie Ahern is a vote for Gerry Adams!~~~)
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To: neverdem

Ping!


7 posted on 02/18/2006 3:50:00 PM PST by airborne
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To: Irish_Thatcherite

My prayers are with you (even belately). Alzheimers really has an effect on a family.


8 posted on 02/18/2006 3:50:26 PM PST by Dark Skies ("Free speech is the weapon of choice against islam...not democracy.")
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To: Irish_Thatcherite

My Mother-in-Law had it. She lived with us for two years, and it was not pretty. It is a cruel disease because the person that was once bright, loving and personable becomes a walking mental vegetable. What makes it really bad is that it goes on for decades, gradually.


9 posted on 02/18/2006 3:55:42 PM PST by GeorgefromGeorgia
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To: Coleus

Laura Ingraham had a guy on Thursday or Friday that stated there are 65 different programs where adult stem cells were being used currently to help people with ailments. There are zero with embryonic stem cells.

This individual also stated that there is a problem with embryonic stem cells in that they seem to case tumors. He stated that he wasn't sure the tumor problem could be overcome, but acknowledged that it might.

He then commented that if there were truly a raging promise of success with embryonic stem cells, you wouldn't be able to stop corporations from plunging into the field. Presently none are doing so. So much for all the hype and promise.


10 posted on 02/18/2006 3:56:35 PM PST by DoughtyOne (If it's a "Religion of Peace", some folks aren't very religious.)
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To: Dark Skies

Thanks.


11 posted on 02/18/2006 3:58:42 PM PST by Irish_Thatcherite (~~~A vote for Bertie Ahern is a vote for Gerry Adams!~~~)
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To: Dark Skies
My mother has Alzheimer's and I'm her caretaker. I'm still able to work but it's close to the point where I'll have to quit. I'm trying to save as much as I can to stay home with her.

She has other serious medical problems and the Alzheimer's is just starting to advance but it's definitely the worst of her problems. Strictly physical ailments are easier to deal with.

12 posted on 02/18/2006 3:58:44 PM PST by NEPA (Give war a chance)
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To: GeorgefromGeorgia
What makes it really bad is that it goes on for decades, gradually.

I know, my grandmother had it for 30 years.

13 posted on 02/18/2006 3:59:51 PM PST by Irish_Thatcherite (~~~A vote for Bertie Ahern is a vote for Gerry Adams!~~~)
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To: GeorgefromGeorgia

It is a cruel disease, harder on the family than on the patient. My grandpa has it and it makes me sad when I think how he used to be versus his present circumstances.


14 posted on 02/18/2006 4:10:39 PM PST by Cyclopean Squid (History is a work in progress)
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To: Coleus
Plaque, not plague!

Sheesh, you'd think that the upi "journalist" would know the difference.

AV

15 posted on 02/18/2006 4:19:22 PM PST by Atomic Vomit (www.aroostookbeauty.com)
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To: Atomic Vomit
Oops! Ignore that....my fonts make the "q" look like a "g".

Oh well...

AV

16 posted on 02/18/2006 4:21:27 PM PST by Atomic Vomit (www.aroostookbeauty.com)
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To: Paleo Conservative
This is outrageous to suggest it isn't necessary to tear apart human fetuses to get stem cells.

What's ourtageous about this?

17 posted on 02/18/2006 5:05:06 PM PST by marvlus
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To: marvlus
This is outrageous to suggest it isn't necessary to tear apart human fetuses to get stem cells.

What's ourtageous about this? ==============================================

Paleo Conservative was being sarcastic

18 posted on 02/18/2006 5:20:45 PM PST by sockmonkey
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To: marvlus

Bone marrow stem cells do not come from fetuses. They come from bone marrow.


19 posted on 02/18/2006 5:30:33 PM PST by Chickensoup (The water in the pot is getting warmer, froggies.The water in the pot is getting warmer, froggies.)
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To: NEPA

My heart (and prayers) go out to you. We helped care for my father-in-law as he battled the disease. I will tell you that a sense of humor helped us all. Among the things this wonderful man lost was his memory of picky eating. The guy ate EVERYTHING in the late years. It was one of the things we spoke of after he passed and it still gives us chuckles.

The only blessing was that we had said good-bye to the real man long before we said good-bye to his earthly body.


20 posted on 02/18/2006 5:32:09 PM PST by trimom
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