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Niacin May Protect Against Alzheimer's (and other mental decline)
Reuters ^ | July 15, 2004 | Anthony J. Brown, MD

Posted on 07/15/2004 9:46:53 PM PDT by FairOpinion

NEW YORK (Reuters Health) - High intake of the vitamin niacin, particularly from food sources, may reduce the risk of Alzheimer's disease and age-related mental decline, according to a new report.

The study in the Journal of Neurology, Neurosurgery, and Psychiatry points out that severe niacin deficiency is known to cause dementia. However, the researchers note that it is unclear if more subtle variations in niacin intake influence the risk of mental deterioration.

"There have been no epidemiologic studies to look at the association between dietary niacin and Alzheimer's disease or cognitive decline," lead author Dr. Martha C. Morris, from the Rush Institute for Healthy Aging in Chicago, told Reuters Health.

Moreover, "animal studies and other studies have really focused on the effects of very high therapeutic dose levels of niacin," not amounts found in a standard diet.

To investigate, the researchers asked several thousand elderly people living in a Chicago community about the types and amounts of food they ate and tested their mental abilities.

The study focused on 815 randomly selected subjects who were free from Alzheimer's disease at the start of the study. After an average of nearly four years, 131 of the participants were diagnosed with Alzheimer's disease.

A high level of total niacin intake seemed to protect against both Alzheimer's disease and cognitive decline. The association was stronger for niacin intake from foods than for niacin taken in vitamin supplements.

"We were surprised to see a fairly strong association between niacin intake from foods and Alzheimer's disease," Morris said. Compared with the lowest intake, the highest intake "was linked to an 80 percent reduction in risk."

In the overall study population, high niacin intake was also linked to a reduced risk of cognitive decline.

Although the finding are provocative, Morris concluded, they will require verification before any changes to current dietary guidelines can be recommended.

SOURCE: the Journal of Neurology, Neurosurgery, and Psychiatry; August 2004.


TOPICS: News/Current Events
KEYWORDS: aging; brain; dementia; deterioration; health; mental
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To: FairOpinion

I will have to check that site...I seem to remember rice was high in Niacin too. Maybe brown rice?

Thanks for the information. I can work to eat more fish, but NO lamb. I believe it is the recommended lean meat.


21 posted on 07/15/2004 10:10:27 PM PDT by 3D-JOY
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To: FairOpinion

Niacin is also used for Cholesterol control. The main drawback though is large does of Niacin can also be toxic to your Liver.


22 posted on 07/15/2004 10:11:02 PM PDT by Captain Peter Blood
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To: HomersNose

"The very best form of niacin currently available, in my opinion, requires a doctor's prescription. Niaspan is a timed-release form not associated with liver abnormalities and--if taken according to the step-up dosing schedule devised by the manufacturer--is virtually free of the flush effect. In fact, this is still good old-fashioned niacin at heart, just repackaged to circumvent the two most problematic side effects, flushing and liver abnormalities."

Thanks for the link.


23 posted on 07/15/2004 10:11:06 PM PDT by FairOpinion (If you are not voting for Bush, you are voting for the terrorists.)
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To: Pegita

Good info. I started to take B complex, then quit. Think I'll start again.


24 posted on 07/15/2004 10:11:46 PM PDT by Lijahsbubbe
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To: BunnySlippers

I am "too cheap" to pay for vitamins in high doses. I feel like it is both literally and figuratively FLUSHING my limited funds.


25 posted on 07/15/2004 10:16:09 PM PDT by 3D-JOY
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To: All

Night to ALL...need some sleep to go with my vitamins! LOL


26 posted on 07/15/2004 10:19:32 PM PDT by 3D-JOY
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To: 3D-JOY

Triptophan?


27 posted on 07/15/2004 10:27:31 PM PDT by BunnySlippers (Must get moose and squirrel ... B. Badanov)
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To: formercalifornian

LOL


28 posted on 07/15/2004 10:30:14 PM PDT by Maynerd
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To: BunnySlippers
Niacin makes your ears hot and tingly?

So...do you eat it, or apply it directly on the ears?

29 posted on 07/15/2004 10:59:57 PM PDT by Graymatter (Media love fest---2 Johns and a thousand presstitutes.)
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To: Graymatter
Haha! It won't cost you much but go down to your local drugstore/supermarket. Buy a bottle of niacin. Take whatever the directions say to take. Wait about 20 minutes. Your skin will flush, you'll feel hot and tingly. If you decide to continue (and you may not) ... the feeling will subside over a few weeks.

Have fun!

30 posted on 07/15/2004 11:43:11 PM PDT by BunnySlippers (Must get moose and squirrel ... B. Badanov)
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To: FairOpinion

31 posted on 07/16/2004 2:20:05 PM PDT by perfect stranger
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