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Study casts doubt on gluten as cause of gut ailments among non-coeliacs
The Guardian ^ | 3/26/2025 | Donna Lu

Posted on 03/26/2025 10:03:27 PM PDT by logi_cal869

People who report being gluten intolerant but do not have coeliac disease may be experiencing gut symptoms unrelated to gluten intake, new research suggests.

A study involving individuals with self-reported gluten sensitivity has found that they experienced gut symptoms such as bloating and abdominal pain regardless of whether or not they consumed gluten.

Assoc Prof Jessica Biesiekierski of the University of Melbourne, one of the study’s senior authors, said the findings were significant in light of popular blame on gluten as a trigger for various symptoms.

AirPods Pro 2 Australians can now use Apple AirPods Pro as hearing aids – but experts warn they’re not for everyone Read more Only about 1% of people in western countries have coeliac disease, an autoimmune condition in which gluten causes an inflammatory reaction in the small bowel.

“Coeliac disease is a well-defined medical condition. It has a clear diagnostic pathway,” Biesiekierski said. For people with coeliac disease, a gluten-free diet is the only effective treatment option.

However, about 10% of the population self-report being gluten sensitive. “We’ve got this large number of people who are following a gluten-free diet, possibly unnecessarily,” Biesiekierski said.

- snip -

Individuals with gluten-sensitivity reported increased fatigue after both the gluten and placebo yoghurt compared to healthy controls. They also reported increased pain and bloating with both the gluten and gluten-free muffins.

Urine, blood and saliva samples taken for cortisol levels and markers of inflammation showed no differences after gluten ingestion.

“Participants continued to report gastrointestinal symptoms, but these symptoms didn’t appear to be specifically triggered by gluten,” Biesiekierski said. Researchers believe the response to gluten may be explained by a nocebo effect, the opposite of the placebo effect, in which a negative outcome results from an expectation that the treatment will be harmful.

(Excerpt) Read more at theguardian.com ...


TOPICS: Chit/Chat
KEYWORDS: celiac; coeliacdisease; gluten; gut
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To: nickcarraway

Thanks. I’ll check it out.

That’s a lot per appointment, and I get that they are providing a great service and need to earn their living, but still...... That’s a lot to swallow.

But I am by default suspicious about people who demand full payment up front. It just doesn’t sit well.


21 posted on 03/27/2025 12:14:31 AM PDT by metmom (He who testifies to these things says, “Surely I am coming soon." Amen. Come, Lord Jesus)
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To: logi_cal869

It is more likely caused by histamine intolerance.

Same with IBS.


22 posted on 03/27/2025 12:49:58 AM PDT by tired&retired (Blessings )
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To: logi_cal869

If people would try two enzymes as supplements, they could possibly find the cause.

1. Alpha galacto sidase, it’s available at Walmart, $5 for 100 tablets.

It’s the same ingredient in Beano. It chops long chain sugars such as polysaccharides and disaccharides into short chain monosaccharides that the body can digest. This prevents fermentation problems in the intestines. It’s a natural pancreatic enzyme for digesting starches.

2. Diamine Oxidase. It’s an enzyme that degrades histamines in the body that cause inflamation, congestion, joint pain, brain fog, stomach acid issues, and digestion.


23 posted on 03/27/2025 1:00:01 AM PDT by tired&retired (Blessings )
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To: logi_cal869

Never tried GF. Sometimes I feel a bit too tired after a meal and I know that some people cannot tolerate that and choose GF because of it.

It is really difficult to pinpoint the problem and to find a single part in your diet that is to blame.

The secret is experimentation, observation and patience. There are more than enough healthy food choices, and getting the quantities right combined with moderate exercise should solve most problems.


24 posted on 03/27/2025 1:40:39 AM PDT by NearlyDone
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To: logi_cal869

Well, there goes that industry!


25 posted on 03/27/2025 2:26:52 AM PDT by The Duke (Not without incident.)
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To: logi_cal869

The problem with gluten free stuff, imho, is that it needs GLUTEN!

[Thanks, John Pinnette...]


26 posted on 03/27/2025 2:35:54 AM PDT by Adder (End fascism...defeat all Democrats.)
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To: logi_cal869

Being bloated after eating wheat grown on n the USA (GMO) is a slight allergic reaction. You won’t get that reaction when eating pasta milled and grown in Europe. (Non GMO).
The gmo wheat grown here is modified to grow faster which grows harder which makes it harder for your body to digest it.
I have went off USA flour years ago and now have a nasty reaction to it. However, European flour and wheat, I’m fine. Several other friends with similar reactions are fine eating European wheat.


27 posted on 03/27/2025 2:46:18 AM PDT by mikelets456
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To: logi_cal869

It well not convince the true believers.

Being gluten free is far more a cult then other wise.


28 posted on 03/27/2025 2:55:05 AM PDT by riverrunner
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To: nickcarraway

Wheat allergy is real and may be what many people who have “gluten sensitivity” actually have. Food allergies are common. Symptoms of an allergy to one food may be different than the alletgy symptoms of another food.


29 posted on 03/27/2025 3:15:30 AM PDT by vivenne (7Come to think of it. )
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To: riverrunner

“Being gluten free is far more a cult then other wise.”

Those I’ve known who are theatrical about being GF are focused more on attention than actual issues. They also find other ways to get the attention they want/need.

Probably those with legit gluten issues manage their diets quietly. without fanfare, and live their lives.


30 posted on 03/27/2025 4:01:53 AM PDT by MayflowerMadam (It's hard not to celebrate the fall of bad people. - Bongino)
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To: logi_cal869

Many people feel better going GF just because their diet is changed. These days GF products seem to have more chemicals and calories than old school GF where you just do without certain food groups.


31 posted on 03/27/2025 4:06:20 AM PDT by greatvikingone
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To: logi_cal869

No particular gut problems but on an elimination diet nowadays tbe behest of a functional medicine doctor. Odd excema/psoriasis outbreak.

No flours. No grains no seed oils No dairy. No sugars.

Selected beef and chix and veggies

Appears to be marginally improving.

Giving it 3 months


32 posted on 03/27/2025 4:34:20 AM PDT by Chickensoup
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To: logi_cal869

Certain proteins can also induce the same symptoms..............


33 posted on 03/27/2025 4:46:29 AM PDT by Red Badger (Homeless veterans camp in the streets while illegals are put up in 5 Star hotels....................)
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To: nickcarraway

They altered the wheat to make it more productive, in order to feed the world. The stalks are top-heavy with kernels and bred to be short, so that they won’t break. This “dwarf wheat” is the stuff we eat nowadays. However, no attention was paid to the potential of other alterations accompanying the effort to make the stalks more productive. Thus, we now have all these medical problems tied by some to modern wheat.


34 posted on 03/27/2025 4:49:02 AM PDT by Tolerance Sucks Rocks (FBI out of Florida!)
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To: Chickensoup

If you have a gut issue - which imho is likely based upon your brief description - be sure to have the test which also checks for parasites etc. (it’s comprehensive...and expensive. >$400 out of pocket).

Otherwise, you may be wasting your time, and the symptoms will reappear. We’re all unique in some respect genetically and symptoms will vary. In my case it manifested in adult acne (among other weird symptoms), overlapping also as a reaction to foods I now enjoy (save for one poison I avoid perpetually: Palm oil).

And, btw, it will take much longer than 3 months to permit gut healing. Fair warning. I hope you achieve your goal.


35 posted on 03/27/2025 6:14:28 AM PDT by logi_cal869 (-cynicus the "concern troll" a/o 10/03/2018 /!i!! &@$%&*(@ -)
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To: riverrunner
Being gluten free is far more a cult

>>THAT!!!

36 posted on 03/27/2025 6:15:47 AM PDT by logi_cal869 (-cynicus the "concern troll" a/o 10/03/2018 /!i!! &@$%&*(@ -)
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To: TheWriterTX

THREE DAYS???!!!

You’re quite lucky. I had systemic candida for over 30 years (a retrospective analysis revealed that fact).

It took me a full year to eradicate and then another full year to heal my gut. Symptoms finally started dropping off after a number of months (not days). Now 100% normal, zero allergies and >60 individual impaired health symptoms reversed.

Kudos to you...and your doctor. We are 2 rare birds.

And something tells me that GF had nothing whatsoever to do with your recovery ;-)


37 posted on 03/27/2025 6:27:46 AM PDT by logi_cal869 (-cynicus the "concern troll" a/o 10/03/2018 /!i!! &@$%&*(@ -)
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To: nickcarraway

I did not have that luxury.

I did, however, put the entire experience - and all supporting research - into a 4-volume book (unpublished).

I’ve since decided not to publish as a book per se (long story), but possibly to pursue a higher degree (a longshot) or secure a credentialed co-author to publish in a format for physicians.


38 posted on 03/27/2025 6:31:11 AM PDT by logi_cal869 (-cynicus the "concern troll" a/o 10/03/2018 /!i!! &@$%&*(@ -)
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To: logi_cal869
I have a celiac family member. Celiac disease can only be diagnosed through a biopsy of the gut. Many people who use gluten free products don't realize that they are loaded with fats and sugars to make them more palatable. A true gluten free diet consists of items you find in the perimeter of the grocery store; meats, veggies and fruits that all need to be refrigerated, hence their perimeter location. Even some meats should be carefully inspected for injections that may contain gluten (chicken and turkey, especially). The USDA allows for some gluten contamination while still being able to carry the Gluten Free badge. Only items certified GF by the Celiac Sprue Association come from sources that are truly gluten free. This issue applies to the US only, as Canada and Europe do not allow any contamination of labeled gluten free foods.

Even celiacs sometimes need to go further in their restrictions to heal the damage done to their gut. The Specific Carbohydrate Diet is very helpful for those who have experienced some success on GF but still don't feel 100% better.

39 posted on 03/27/2025 6:50:43 AM PDT by liberalh8ter ( This tagline has taken the month off to attend the inauguration.)
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To: liberalh8ter

Some people are genetically predisposed to develop coeliac disease, an immune system reaction within the gut itself.

But I believe for many the disease is preventable, triggered within the gut on the basis of the patients’ own actions.

I am a firm believer in the idiom ‘all things in moderation’ and that our food system is nearly irreconcilably toxic.

If consumers don’t make good choices to change market demands - including prodding their congresscritters...another discussion altogether - nothing will ever change for the bulk of the populace.

Truly Russian Roulette...but in most cases with a very, very slow poison.


40 posted on 03/27/2025 7:17:42 AM PDT by logi_cal869 (-cynicus the "concern troll" a/o 10/03/2018 /!i!! &@$%&*(@ -)
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