Dozens of new obesity drugs are coming: these are the ones to watch

I see class action lawyers will have no shortage of employment in the decades to come.

Yep.

While they are puffing away on their vapes, watching tentacle porn and checking their messages every 60 seconds or whatever.

All God's children have something they wrestle with and I imagine food is one of the hardest. Because while you can just put many things down you still have to eat. Or you die.

One of the most messed up nonpolitical story for this year is that fast food companies are working on GLP1RA blockers as additives to neutralize the effects of meds like Oz.

‘I’ve included some related questions if you like me to post any of those.’

Yes please. Just a reminder, Perplexity knowledge base is the current scientific ‘research’, which is filled with pseudo science, especiaĺly nutrition studies. Perplexity does NOT discern good from bad and will put out all the official nonsense about ‘healthy’ eating.
But it recognizes there are several levels of quality of datas (observatinal and retrospective data are the worst but are everywhere in nutrition ‘science’) and can change its opinion when contradicted with logics and datas. What is awesome is those changes are stored permanently in its weights.
I recently confronted it on the ‘blue zones’ and it finally admitted that the blue zones concept is a big fat lie, apologized profusely and will never use it again as an argument to promote plant based diets and criticise meat. That was a fascinating ‘conversation’, I should probably publish it as an article.

Exercise is NOT a solution for someone who has plenty inflammation and joints pain which most obese people suffer. It a sure way to wreck their health, especially with cardiac and fall accidents.
The solution is to wean out medicines and to fix the diet first. The saying ‘you can’t outrun a bad diet” is always true,

what are the names of beneficial gut bacteria. what probiotics or foods have these beneficial bacteria. what are their benefits?

Several beneficial gut bacteria play important roles in maintaining our health. Here are some key probiotic strains and their benefits:
Lactobacillus acidophilus: Found in yogurt and fermented soy products. It produces lactic acid, lowers gut pH, stimulates the immune system, enhances nutrient absorption, and improves digestive health1.
Bifidobacterium bifidum: Present in fermented foods like kefir and yogurt. It breaks down complex carbohydrates, produces short-chain fatty acids, stimulates the immune system, and reduces inflammation1.
Lactobacillus plantarum: Found in fermented foods like kimchi, sauerkraut, and pickles. It produces antimicrobial compounds, stimulates the immune system, improves digestion, and reduces inflammation1.
Streptococcus thermophilus: Present in fermented dairy products like yogurt and cheese. It produces lactase to break down lactose, stimulates the immune system, and improves digestive health12.
Enterococcus faecium: Found in fermented foods like cheese and sausage. It produces antimicrobial compounds, stimulates the immune system, and improves gut health1.
Lactobacillus rhamnosus GG: May help treat certain conditions, though specific benefits were not detailed in the search results3.
Bifidobacterium infantis: Thought to help relieve symptoms of IBS, such as abdominal pain, gas, and bloating3.
Saccharomyces boulardii: A beneficial yeast found in many probiotic supplements. It may help prevent and treat traveler’s diarrhea, antibiotic-associated diarrhea, and acne3.
Probiotic-rich foods include:
Yogurt
Kefir
Kombucha
Sauerkraut
Pickles
Miso
Tempeh
Kimchi
Sourdough bread
Some cheeses8
The benefits of consuming these beneficial bacteria include:
Supporting gut microbiota health
Preventing or delaying gastrointestinal disorders
Potentially benefiting conditions like obesity, type 2 diabetes, autism, osteoporosis, and some immunological illnesses
Enhancing intestinal, nutritional, and oral health
Improving digestion
Supporting a healthy immune system
Reducing inflammation
Producing short-chain fatty acids, particularly butyrate, which fuels enterocytes
Preventing pathogenic bacteria adherence
Producing anti-bacterial substances
Decreasing luminal pH4
While there’s no specific recommended daily intake for probiotics, incorporating a variety of fermented foods into your diet can help increase your intake of these beneficial bacteria

How do probiotics in supplements compare to those found in fermented foods

Probiotics in supplements and fermented foods differ in several key ways:
Diversity: Fermented foods generally provide a larger variety of beneficial bacteria compared to probiotic supplements3. This diversity is important for maintaining a healthy gut microbiome.
Viability: Probiotic supplements face challenges in keeping microbes viable in encapsulated tablets2. Fermented foods, on the other hand, often contain live cultures that are more likely to survive and colonize the gut.
Strain specificity: Probiotic supplements typically contain specific strains of bacteria, while fermented foods may have a broader, less controlled mix of microorganisms27.
Additional benefits: Fermented foods offer more than just probiotics. They provide digestive enzymes, increased nutrient bioavailability, and reduced anti-nutrients6. These foods also undergo partial digestion during fermentation, making them easier for the body to process6.
Regulatory oversight: Probiotic supplements do not have the same FDA oversight as medications1. Fermented foods, being whole foods, are subject to different regulations.
Cost-effectiveness: Fermented foods are often more cost-effective for obtaining probiotics compared to supplements3.
Natural vs. isolated: Fermented foods provide probiotics in a natural food matrix, which may enhance their effectiveness, while supplements offer isolated strains13.
Consistency: Probiotic supplements provide a consistent dose of specific strains, whereas the probiotic content in fermented foods can vary7.
While both sources can be beneficial, many experts recommend obtaining probiotics from fermented foods when possible, reserving supplements for specific health concerns as advised by a healthcare professional1

You did not mention L Reurteri in the list of beneficial gut bacteria. Why not?

I apologize for the oversight in not mentioning Lactobacillus reuteri (L. reuteri) in the previous list of beneficial gut bacteria. L. reuteri is indeed an important probiotic strain with numerous health benefits. Here’s why it should have been included:
L. reuteri is a well-studied probiotic bacterium that can colonize the gastrointestinal tract, urinary tract, skin, and breast milk in humans1.
It offers several health benefits, including:
Producing antimicrobial molecules to inhibit pathogenic microbes1
Strengthening the intestinal barrier12
Boosting the immune system2
Reducing inflammation1
Promoting regulatory T cell development and function1
L. reuteri has shown potential in preventing and treating various conditions such as:
Colic in infants3
Diarrhea3
Constipation3
H. pylori infection3
High cholesterol3
It can be found in some fermented foods and is also available as a probiotic supplement3.
Recent research has shown promising results in using L. reuteri for treating inflammatory bowel diseases, colorectal cancer, and pediatric intestinal disorders4.
L. reuteri is an important beneficial gut bacterium that should have been included in the previous list due to its wide range of health benefits and potential therapeutic applications.

You did not mention L Reurteri in the list of beneficial gut bacteria. Why not?

I apologize for the oversight in not mentioning Lactobacillus reuteri (L. reuteri) in the previous list of beneficial gut bacteria. L. reuteri is indeed an important probiotic strain with numerous health benefits. Here’s why it should have been included:
L. reuteri is a well-studied probiotic bacterium that can colonize the gastrointestinal tract, urinary tract, skin, and breast milk in humans1.
It offers several health benefits, including:
Producing antimicrobial molecules to inhibit pathogenic microbes1
Strengthening the intestinal barrier12
Boosting the immune system2
Reducing inflammation1
Promoting regulatory T cell development and function1
L. reuteri has shown potential in preventing and treating various conditions such as:
Colic in infants3
Diarrhea3
Constipation3
H. pylori infection3
High cholesterol3
It can be found in some fermented foods and is also available as a probiotic supplement3.
Recent research has shown promising results in using L. reuteri for treating inflammatory bowel diseases, colorectal cancer, and pediatric intestinal disorders4.
L. reuteri is an important beneficial gut bacterium that should have been included in the previous list due to its wide range of health benefits and potential therapeutic applications.

Thank you for the Perplexity.ai answers. As expected, it makes assessments on probiotics based on the nutrition echo chamber, which is essentially marketing based on hype and pseudo science.
Perplexity itself recognizes all the supposed health benefits are just claims by using conditionals like “can, may, might”.
Ask it if any of those claims are backed up by good level of confidence data such as physiological studies or randomized trials on big samples or how the purported efficacy is evaluated and you’ll see how bad the science is.
Ask it why probiotics are supposed to colonize the digestive tract yet must be taken again and again and it will admit there is incoherence and lack of logic.

The role of bacteria in digestion and over all health has only become prominant in the last decade.

Perhaps its all based on hype.

So how do you evaluate the role of bacteria in digestion and overall health.