Is there a genetic predisposition to unappreciated?
Posted on 02/02/2025 8:04:57 AM PST by ConservativeMind
Polygenic scores (PGS) are metrics used to estimate the genetic predisposition of people to developing specific mental health conditions, personality traits or diseases. In recent years, these metrics have often been used to investigate the intricate connections between genes and environmental factors.
Researchers recently carried out a study aimed at determining whether neuropsychiatric polygenic scores could predict the professional categories that individuals belong to. Their findings suggest that these scores weakly predict the professional category that people belong to.
Specifically, they wished to determine whether PGS scores hinting at a predisposition for specific neuropsychiatric disorders, such as autism spectrum disorder (ASD) or schizophrenia, are predictors of the membership to specific professional categories (e.g., "computers & math," "arts & design," etc.).
To determine whether a slightly higher predisposition for specific psychiatric traits was aligned with a person's profession, the researchers analyzed data collected as part of two of the world's largest biobanks. One of these is the Million Veteran Program (MVP), which is run in the US, while the other is the UK Biobank (UKBB), collected in the UK.
"A major takeaway is that while we do see statistically significant associations between several neuropsychiatric traits and professional categories, each trait's polygenic score (PGS) explains less than 0.4% of the variation in whether a person enters a particular profession," said Voloudakis. "In other words, there is a real but weak genetic signal in these career placements."
Interestingly, the researchers found that both age and sex played a far greater role in determining the professions that individuals will pursue compared to neuropsychiatric PGSs. Age accounted for approximately 21% of the observed variance in profession, while sex accounted for 7%.
"Our findings emphasize that demographic and social factors far outweigh genetic predisposition when it comes to occupational outcomes," explained Voloudakis.
(Excerpt) Read more at medicalxpress.com ...
“ For example people who go into “mental health” are nuts.”
They either become mental health professionals or democrat politicians.
Everything looks like a nail to me so I became a carpenter.
You asked for it.
“Polygenic scores (PGS) are metrics used to estimate the genetic predisposition of people to developing specific mental health conditions, personality traits or diseases.”
I’ve always wanted to do a study on people that back in to parking spaces.
“…know people with some of these conditions in some of these expected professions.”
And perhaps as many or more who do not?
Is there a genetic predisposition to unappreciated?
Leave me alone in the back lab and I’m thrilled
‘You asked for it.’
Absolutely! Enjoying every response!
Ever met an accountant with a sense of humor?
A plumber who leaves the seat down?
An auto mechanic who wears designer clothes?
Oh, poor “ArtDodger”—I see you’re trying to avoid your obvious “arts & design” classification.
The table says you are very high-strung.
Try working in a hospital.
Everyone in the place is batsh!t crazy.
And then there’s the patients.....
Some of the people I worked with were nuts. Some had some screws loose-not surprising, since I worked in machine shops.
>> we can rule out ‘musician’...
🤣
>> it’s saying engineers are skewed in the direction of being/valuing... agreeableness.
The researchers clearly don’t attend the same meetings that I do. 😆
When I started a job at a factory, two other workers walked up to me. The man said, “You know we’re all crazy here, right?” The woman added, “And now, you’re one of the crazies, too!”
👍🙂
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