Posted on 12/06/2024 4:38:27 PM PST by ConservativeMind
Healing the gut may be the key to improving long-term recovery in stroke patients, scientists have found.
The team demonstrated how a drug that was effective at protecting the brain in the immediate aftermath of a stroke failed to prevent long-term cognitive impairment when applied only to the brain. The same drug, when applied to the gut, reduced impairment significantly.
What happens in the gut after a stroke?
Within mere moments of a stroke, patients experience a cascade of symptoms, many of which are immediately apparent, Sohrabji said.
Less apparent, is the damage being done to key structures in the intestine, as the brain communicates to the gut that something is wrong. "What we've found is that minutes after a stroke occurs, normal gut anatomy is completely disrupted," Sohrabji explained.
Most notably, cells responsible for keeping the contents of the gut sealed off from the rest of the body begin to erode, allowing digestive bacteria to leak out and cause harm to other bodily systems. Under certain conditions, Sohrabji said, these bacteria can end up in the brain itself and disrupt its functioning.
Even if bacteria don't make it all the way to the brain, brain function can still be impaired as the body's immune system recognizes the threat and mounts an inflammatory response to fight it. Increased inflammation exacerbates the impact of a stroke, further injuring the brain and increasing long-term cognitive impairment.
In the study, a treatment applied directly to the gut—a dose of Insulin-like Growth Factor or IGF-1—was shown to significantly reduce post-stroke inflammation and cognitive impairment. Sohrabji and her team's investigation showed that the structures in the gut that become damaged after a stroke appeared to be repaired by the IGF-1 treatment, reinforcing the idea that healing the gut is crucial in facilitating stroke recovery.
(Excerpt) Read more at medicalxpress.com ...
Thank you! I’m continuing praying for you and your son.
Thank you
Thank you so much.
Thanks Judy for posting and thank you all for prayers. This was so sudden and unexpected, really reminds us of living and being our best every day. And thanking God for every precious moment!
I don’t know if they have figured out the cause yet, haven’t talked to my son in 3 hours. I read that even an untreated infection can cause organ failure. But she wasn’t feeling well just a few days. Doctor was not happy the ER didn’t even do lab work.
I pray she pulls through, it’s scary but she’s a normally healthy person, gets exercise and no bad habits.
Still praying for all here with sickness in the family.
Thanks Jane. It’s so weird, she didn’t have any previous issues, healthy, no bad habits.
Thank you!
Thanks, I appreciate it. I’m on your ping list, so appreciate your health knowledge. I didn’t know kidney failure causes fever, headache and earache. Apparently neither did the ER doctor. That must be why her doctor was upset that they didn’t even do lab work. I’ll ask my son about her consumption.
Thank you so much. Did you see her liver is shutting down now too? I guess our organs are all interrelated.
I haven’t talked to my son in about 3 hours, this cripple took my crippled granddaughter to the store. She got real nauseated and in pain.
That’s good to know about the gut/ stroke.
I’m sorry I hijacked this thread about my DIL but I thought maybe on this thread some folks might have some helpful knowledge.
I’m still praying!! Praying that they can zero in on, and, cordon off the cause of this attack on her organs....by treating the root cause (infection??).
Bless you, all ... you are having a time of it with the ailments/surgeries/hospitals.
Is your granddaughter taking meds with codeine? I cannot take that ... I get really sick (nauseous). Also ... taking pain (and other meds, too) on an empty stomach can cause nausea.
Please let me know when you hear back from your son.
Praying in His Holy name for His healing over your DIL.
I got rid of IBS and a I’d problems by taking a probiotics with T least 11 strains and NOT taking Tagament, Zantec, etc.
She’s taking a low dose hydrocodone so that could be it.
I took that for over a year and it didn’t bother me, other than making me want key lime pie all the time.
Itext my son if I don’t hear from him in a bit. He and the kids had to leave so she could rest and I figure he probably needs rest too if he can.
Oh Rusty!
I am so very sorry to hear this!
Prayers lifted for your son and DIL
and for you, too!
That is so frighting!
I wonder what brought this on?
Prayers, prayers, and MORE prayers!
Sending love to you!
Ms. B
Just read about your DIL. I’m posting your request NOW!
Disclaimer: Opinions posted on Free Republic are those of the individual posters and do not necessarily represent the opinion of Free Republic or its management. All materials posted herein are protected by copyright law and the exemption for fair use of copyrighted works.