Researchers evaluate beneficial effects of fermented black garlic extract on prostate cancer

Medical Xpress / University of Córdoba / Nutrients ^ | Oct. 15, 2024 | Maria Loreta Libero et al

[ConservativeMind]

A team tested the protective effect of a fermented black garlic extract against inflammation and the progression of prostate cancer in a study conducted on human prostate cancer cell models in the laboratory.

Prostate cancer may progress from benign hyperplasia (growth of the prostate) to localized prostate cancer, or to metastatic castration-resistant cancer, for which few drugs are available.

María Loreta Libero recently studied the beneficial effects of a fermented black garlic extract on prostate cancer cells. Taking into account a previous experiment in mice in which the extract was found to have anti-inflammatory characteristics, and considering the important role of inflammation in prostate cancer, they decided to evaluate its effect on cellular models of human prostate cancer.

"We tested the extract in different human prostate cancer cell models, and found that it was capable of reducing various tumor aggressiveness parameters, including cell proliferation," explained researcher Montero. "We also found that it did not affect normal prostate cells." In this way, he indicated, this compound could be administered as a dietary supplement without potentially negative effects on healthy prostate cells.

Luque, explained how, after demonstrating the compound's anticancer effects. "The treatment decreases the inflammatory environment that you can see in this type of cancer."

The extract was more effective and was able to produce more changes when the cells were in a pro-inflammatory environment. The local inflammation could be related to the aggressiveness of the cancer, and the fact that this extract acts on it could be due to its reduced aggressiveness after the extract treatment.

According to Luque, "Everything indicates that this compound could be a very good option to avert some of the adverse events that occur in patients who are going to progress to a more complex and aggressive stage of prostate cancer."

[ConservativeMind]

It would appear fermented black garlic extract reduces the localized inflammation within the cancerous are of the prostate, which reduced tumor aggressiveness and proliferation.

Fermented black garlic extract is available from health food stores and places like Amazon.

[ConservativeMind]

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[TheThirdRuffian]

Works great, but the application is a bit intimidating

J/k

[Organic Panic]

At least we won’t have to worry about garlic breath....

[Robert357]

Bump for reference

80% of 80-year old men either have or have been treated for prostate cancer, although most die of other things.

[CTyank]

My Dad was told he had prostate cancer and it might kill him if he lived to be 140.