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A camu-camu fruit extract to reduce liver fat shows promise in clinical trial (16% reduction)
Medical Xpress / Laval University / Cell Reports Medicine ^ | Aug 21, 2024 | André Marette et al

Posted on 08/25/2024 7:59:22 AM PDT by ConservativeMind

A research team has shown the benefits of camu-camu on non-alcoholic fatty liver disease. This exotic fruit reduces liver fat levels.

Over 12 weeks, thirty participants took either camu-camu extract or a placebo at different times in this randomized clinical trial. Participants underwent magnetic resonance imaging (MRI) to determine fat levels in the liver. Scientists observed a 7.43% reduction in liver lipids when study participants took camu-camu extract. With the placebo, they noted an 8.42% increase in liver fat.

"That's a significant 15.85% difference," says André Marette.

This effect stems from the polyphenols contained in camu-camu and their relationship with the intestinal microbiota. "The microbiota metabolizes the large polyphenol molecules that cannot be absorbed by the intestine, transforming them into smaller molecules that the body can assimilate to decrease liver fat," explains André Marette.

His team has identified two potential mechanisms of action for these small polyphenols. "They could reduce lipogenesis, i.e., the formation of lipid droplets in the liver. They could also stimulate lipid degradation by oxidation. A combination of the two mechanisms probably explains the high efficacy of the extract, as we're playing on both sides of the coin," reports Professor Marette.

However, the team noted a wide variability in response to camu-camu. "We hypothesize that the initial intestinal microbiota influences the response to polyphenols. If we find the factors involved, we may be able to modify the microbiota and increase the extract efficacy," explains Professor Marette.

Although camu-camu is an exotic fruit, the extract is readily available in capsule form. However, Professor Marette stresses the importance of checking the content of certain polyphenols, as not all commercial products are equivalent.

Cranberries could also have a protective effect. In the future, Professor Marette hopes to investigate whether combining camu-camu and cranberry could have a synergistic effect.

(Excerpt) Read more at medicalxpress.com ...


TOPICS: Health/Medicine
KEYWORDS: camucamu; extract; fat; fattyliver; fruit; liver; liverdisease
It appears gut bacteria break down antioxidants in camu-camu, which can then pass through the intestinal wall.

The beneficial effect provided a 15.85% improvement versus placebo.

Camu-camu is commonly available as a powder or extract. We have recently been using it in bulk powder (not extract) form for a Vitamin C boost (it has very high Vitamin C levels) throughout the day. The one we use is from Terrasoul.

1 posted on 08/25/2024 7:59:22 AM PDT by ConservativeMind
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To: Mazey; ckilmer; goodnesswins; Jane Long; BusterDog; jy8z; ProtectOurFreedom; matthew fuller; ...

The “Take Charge Of Your Health” Ping List

This high volume ping list is for health articles and studies which describe something you or your doctor, when informed, may be able to immediately implement for your benefit.

Email me to get on either the “Common/Top Issues” (20 - 25% fewer pings) or “Everything” list.

2 posted on 08/25/2024 7:59:53 AM PDT by ConservativeMind (Trump: Befuddling Democrats, Republicans, and the Media for the benefit of the US and all mankind.)
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To: ConservativeMind

Why not just take a Vitamin C supplement? I am experimenting with 1500-2000 mg. daily and will let you know how I am affected.


3 posted on 08/25/2024 8:08:55 AM PDT by silent majority rising (When it is dark enough, men see the stars. Ralph Waldo Emerson)
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To: ConservativeMind

Bflr


4 posted on 08/25/2024 8:15:07 AM PDT by sauropod ("This is a time when people reveal themselves for who they are." James O'Keefe Ne supra crepidam)
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To: silent majority rising

Vitamin C supplements are supposed to be good at warding off illness. I know people (me included) who take a lot when they get sick.


5 posted on 08/25/2024 8:15:32 AM PDT by MikeSteelBe (The South will be in the right in the next war of Northern aggression.)
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To: ConservativeMind

How about just eating less fat in general?


6 posted on 08/25/2024 8:16:17 AM PDT by Lizavetta
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To: MikeSteelBe

Apparently, the body dispenses any excess in urine output. I cannot find any negative research on the effects of it, but liver health is enhanced by its use. The included article describes the benefit of the fruit extract, but gives an indirect benefit of excess vitamin C.


7 posted on 08/25/2024 8:20:42 AM PDT by silent majority rising (When it is dark enough, men see the stars. Ralph Waldo Emerson)
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To: ConservativeMind

8 posted on 08/25/2024 8:24:39 AM PDT by null and void (Don't hallucinate and legislate, don't hallucinate and educate...)
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To: Lizavetta

Eating fat does not result in liver fat. Eating sugar does.


9 posted on 08/25/2024 8:25:26 AM PDT by tarator
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To: tarator

That seems counter-intuitive but it is correct.


10 posted on 08/25/2024 8:36:42 AM PDT by BipolarBob (Three conspiracy theorists walk into the bar . . . . same time . . coincidence? I think not.)
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To: ConservativeMind

11 posted on 08/25/2024 8:39:37 AM PDT by logi_cal869 (-cynicus the "concern troll" a/o 10/03/2018 /!i!! &@$%&*(@ -)
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To: ConservativeMind

I enjoy your medical updates. Good job!


12 posted on 08/25/2024 8:46:52 AM PDT by JPG ("...if you can keep it.")
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To: silent majority rising

>> Why not just take a Vitamin C supplement? <<

Because Vitamin C is NOT the active ingredient.


13 posted on 08/25/2024 9:00:24 AM PDT by dangus
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To: ConservativeMind

Drunks the world over rejoice


14 posted on 08/25/2024 9:03:04 AM PDT by wardaddy (Thank you God for saving president Trump from murder)
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To: ConservativeMind

bump for reference


15 posted on 08/25/2024 12:19:03 PM PDT by Robert357
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To: ConservativeMind

Thanks for the info! Do you order straight from Terrasoul or from another site?


16 posted on 08/26/2024 12:11:32 AM PDT by peggybac (My will is what I wanted. God's will is what I got.)
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To: peggybac
I order directly from the Terrasoul site, but using their 20% off discount code, which they send out a couple times a year.

Otherwise, I get it from Amazon in a smaller form.

If it is something we use a lot, I get their biggest bag(s) with that discount code occasion.

17 posted on 08/26/2024 6:04:36 AM PDT by ConservativeMind (Trump: Befuddling Democrats, Republicans, and the Media for the benefit of the US and all mankind.)
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To: peggybac

I just noticed from an email that there is a sale that ends today at the Terrasoul site that gives 20% off with coupon code GOODBYE20.

We get many items from Terrasoul. Good quality, yet, they have some hard to find items.

https://www.terrasoul.com


18 posted on 08/27/2024 5:36:31 AM PDT by ConservativeMind (Trump: Befuddling Democrats, Republicans, and the Media for the benefit of the US and all mankind.)
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