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Gain-of-Function Mutation Found in Monkeypox
Independent Sentinel ^ | August 18, 2024 | M DOWLING

Posted on 08/18/2024 6:12:21 PM PDT by Red Badger

Mutation L108F in MPXV is a ‘gain-of-function’ mutation, which most likely enhances processivity, changes sensitivity to nucleoside inhibitors, and fidelity of DNA synthesis.

The following information comes via Dr. Peter McCullough’s substack and the Kanan study.

Monkeypox virus is a smallpox-like viral infection transmitted from animals to humans.

In 2022, HHS Secretary Becerra declared US Monkeypox a public health emergency. Monkeypox occurred almost solely in gay or bisexual men with intense sexual contact. They ended up with blisters around the anus, buttocks, or mouth. The emergency ended in 2023.

The primary drug was the Bavarian Nordic Jynneos vaccine. With that and behavioral changes, the emergency dissipated.

As of January 10, 2023, HHS stopped tracking this Clade 2 subtype, resulting in 32,063 cases and 58 deaths. Most who died had advanced HIV disease.

Don’t touch!

A report by Kannan and others indicated that what happened in 2022 almost certainly occurred because of a gain-of-function mutation in one or more genes within the Monkeypox virus. The authors did not speculate whether it happened in a laboratory or nature.

Nevertheless, the lab gain-of-function should be stopped.

A new African outbreak has caused the World Health Organization to declare a global health emergency recently for Monkeypox.


TOPICS: Conspiracy; Health/Medicine; Science; Society
KEYWORDS: bioweapon; gainoffunction; queerpox
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1 posted on 08/18/2024 6:12:21 PM PDT by Red Badger
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To: Red Badger

Remember when it would only make fur grow in the palm of your hand?


2 posted on 08/18/2024 6:15:47 PM PDT by FlingWingFlyer (The Banana Voo Doo Queen is putting illegal scumbags on a Free Ride on the American Dream Express.)
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To: Red Badger

There is no question that it was in a laboratory.


3 posted on 08/18/2024 6:16:13 PM PDT by Jonty30 (Genghis Khan did not have the most descendants. His father had more. )
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To: Red Badger

Captain Trips is only a few months away with these murders


4 posted on 08/18/2024 6:25:11 PM PDT by struggle
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To: Jonty30

They need to waterboard... uh... somebody, and make the little bastard spill his guts.


5 posted on 08/18/2024 6:30:33 PM PDT by OKSooner (The government killed Frank Zappa with an isotope.)
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To: Red Badger
The authors did not speculate whether it happened in a laboratory or nature.

Forget the science, what is the leftist answer to that question?

6 posted on 08/18/2024 6:30:49 PM PDT by TChad
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To: OKSooner

“make the little bastard spill his guts.”

Or spill the little bastard’s guts.


7 posted on 08/18/2024 6:37:23 PM PDT by MayflowerMadam (I'm voting for the convicted felon with the pierced ear. )
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To: Jonty30

Maybe, but gay men’s anuses are a laboratory of vile disease and putrid nastiness.

Don’t be a pervert and put your personal things where nature never intended them to be.


8 posted on 08/18/2024 6:51:14 PM PDT by Alas Babylon! (Repeal the Patriot Act; Abolish the DHS; reform FBI top to bottom!)
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To: Red Badger
Is it Simian 40 in Monkeypox?

It's not like Simian 40 wasn't flagged in the 1960s for all the problems it caused. /sarc

9 posted on 08/18/2024 7:06:47 PM PDT by T.B. Yoits
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To: Red Badger

Gain-of-Function?

There needs to be some scientists publicly flogged then hung.


10 posted on 08/18/2024 7:14:28 PM PDT by Bryan24
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To: Red Badger

Not to worry!

Deep State has a vaccine for this!

https://www.cdc.gov/poxvirus/mpox/vaccines/vaccine-recommendations.html


11 posted on 08/18/2024 7:20:14 PM PDT by mewzilla (Never give up; never surrender!)
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To: mewzilla

https://www.fda.gov/vaccines-blood-biologics/jynneos

Manufacturer not one of the usual suspects this time...


12 posted on 08/18/2024 7:21:17 PM PDT by mewzilla (Never give up; never surrender!)
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To: mewzilla

Oh, boy. They’re coming for the kids. Again...

https://www.cnbc.com/2024/08/16/mpox-vaccine-maker-bavarian-nordic-seeks-critical-approval-for-teens.html


13 posted on 08/18/2024 7:22:23 PM PDT by mewzilla (Never give up; never surrender!)
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To: Red Badger

n 2022, HHS Secretary Becerra declared US Monkeypox a public health emergency. Monkeypox occurred almost solely in gay or bisexual men with intense sexual contact.


repeat LOUD and OFTEN.....................


14 posted on 08/18/2024 7:35:30 PM PDT by PeterPrinciple (Thinking Caps are no longer being issued but there must be a warehouse full of them somewhere.)
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To: Red Badger

“And I heard another voice from heaven, saying, Come out of her, my people, that ye be not partakers of her sins, and that ye receive not of her plagues.” Revelation 18:4


15 posted on 08/18/2024 7:40:21 PM PDT by captmar-vell
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To: FlingWingFlyer

Thank goodness for electrolysis...


16 posted on 08/18/2024 7:42:53 PM PDT by null and void (Don’t hallucinate and legislate)
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To: Red Badger

“Gain of function”

I hate that term - it’s a way to bamboozle people and make it sound, oh, so technical and out of reach of the common plebe.

What’s wrong with, “Dangerous mutation found in Monkeypox”?


17 posted on 08/18/2024 7:50:04 PM PDT by aquila48 (Do not let them make you "care" ! Guilting you is how they control you. )
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To: aquila48

https://en.wikipedia.org/wiki/Gain-of-function_research

Gain-of-function research (GoF research or GoFR) is medical research that genetically alters an organism in a way that may enhance the biological functions of gene products. This may include an altered pathogenesis, transmissibility, or host range, i.e., the types of hosts that a microorganism can infect. This research is intended to reveal targets to better predict emerging infectious diseases and to develop vaccines and therapeutics. For example, influenza B can infect only humans and harbor seals.[1] Introducing a mutation that would allow influenza B to infect rabbits in a controlled laboratory situation would be considered a gain-of-function experiment, as the virus did not previously have that function.[2][3] That type of experiment could then help reveal which parts of the virus’s genome correspond to the species that it can infect, enabling the creation of antiviral medicines which block this function.[3]


appears to be a real thing?


18 posted on 08/18/2024 7:54:32 PM PDT by PeterPrinciple (Thinking Caps are no longer being issued but there must be a warehouse full of them somewhere.)
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To: aquila48

Because gain of function is engineered by humans while dangerous mutation is a natural occurrence.


19 posted on 08/18/2024 8:06:54 PM PDT by webheart
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To: PeterPrinciple

“Gain-of-function research (GoF research or GoFR) is medical research that genetically alters an organism in a way that may enhance the biological functions of gene products.”

I know it’s a technical term, but...

All it is is “man made mutation”, or “experimental mutation”, why come up with a term that no one outside genetics understand.

It’s like “quantitative easing” in economics, when all it means is “money printing”

It’s just an attempt to confuse and obfuscate your common man and make themselves feel important.


20 posted on 08/18/2024 8:13:12 PM PDT by aquila48 (Do not let them make you "care" ! Guilting you is how they control you. )
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