Posted on 06/22/2024 10:10:43 AM PDT by ConservativeMind
The over-the-counter supplement nicotinamide riboside, a form of vitamin B3, increased the walking endurance of patients with peripheral artery disease, a chronic leg condition for which there are few effective treatments.
In a preliminary, randomized, double-blind clinical trial, patients who took nicotinamide riboside daily for six months increased their timed walking distance by more than 57 feet, compared to participants who took a placebo. As expected, walking speed declined in those who took a placebo, because peripheral artery disease causes progressive declines in walking performance.
The scientists recruited 90 people with an average age of 71 who had peripheral artery disease, or PAD, to test the effects of nicotinamide riboside. The supplement is increasingly popular as an anti-aging treatment. Nicotinamide riboside is a precursor for the essential compound NAD, which plays roles in the body related to energy generation, improved blood flow and DNA repair.
Because PAD is associated with problems generating energy within muscle cells, McDermott and Leeuwenburgh thought that nicotinamide riboside, by improving energy generation, could help improve walking in people with the disease.
And indeed that's what they found. Participants taking the supplement walked an average of 23 feet more in a six-minute walking test after six months, while those taking a placebo walked 34 feet less. Those who took at least 75% of the pills they were supposed to take performed even better, adding more than 100 feet to their walking distance, compared to people who took a placebo.
PAD affects more than 8.5 million Americans over the age of 40. Caused by the buildup of fatty deposits in arteries, and associated with diabetes and smoking, the disease reduces blood flow to the limbs, especially the legs. Walking often becomes painful, and the disease typically causes declines in walking ability over time.
(Excerpt) Read more at medicalxpress.com ...
There has been some helpful benefits from it, but newer research shows that getting more of it than your body can quickly use causes your body to create potentially problematic metabolites.
It seems if you have an overt issue you can address, it can be helpful, but if you are already healthy, big doses convert to the problematic metabolites, and it would seem better to take very low doses or a time-release version, in my humble opinion, from what I’ve read.
My wife and I stopped taking it, due to the more recent studies.
When the Fountain of Youth is 25 ft farther for your foe than it is for you.
Prescribe delta-8 gummies and let them enjoy life from their comfy chairs..
you can measure intelligence, but stupid has no units of measure.
The road to he'll is literally paved with good intentions.
JESUS paid a price for you, don't throw it away on being a "good" person. Be a Godly person.
Thanks!
BKMK
Interesting...
“Nicotinamide riboside is a precursor for the essential compound NAD”...Sorry, there is no proof to this assertion. There is no proof that other “B” derivatives help with NAD development/growth. In fact, it’s starting to look like ALL the NAD+ stuff getting pushed in the market and in “scientific” articles such as this are WRONG
Thanks for sharing Oystir...
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