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Study finds antioxidant dietary supplement may help counter systemic sclerosis
Medical Xpress / Louis Pasteur Ctr for Med Research / International Journal of Molecular Sciences ^ | May 17, 2024 | Fukka You et al

Posted on 05/24/2024 9:05:00 AM PDT by ConservativeMind

Autoimmune diseases occur when the body's immune system attacks healthy cells instead of protecting them. Systemic sclerosis (SSc) is one such autoimmune condition characterized by faulty circulatory and immune systems, leading to the occurrence of fibrosis (hardening and scarring of healthy tissue) of the skin and internal organs.

Countering oxidative stress using antioxidant compounds, is therefore, being increasingly explored as a therapeutic strategy.

To this end, a team of researchers has investigated the effectiveness of Twendee X (TwX)—a dietary supplement comprising of a combination of eight active antioxidants—in reducing oxidative stress in SSc mouse models.

Prof. Inufusa says, "Studies have shown that TwX reduces ROS, protects mitochondrial function, and improves cognition and memory."

The eight constituents of TwX include vitamin C, L-glutamine, niacin, L-cystine, coenzyme Q10, vitamin B2, succinic acid, and fumaric acid. The combined antioxidant effect is likely more potent than the activity of either compound alone. Previous studies have demonstrated improvement in cognition, memory, and motor coordination in mouse models of dementia, and reduction in affected region size, oxidative stress, and inflammation in mouse models of ischemic stroke following treatment with TwX.

Based on these findings, the researchers conducted this study to investigate the effects of TwX in a mouse model of SSc created using hypochlorous acid (HOCl).

HOCl induction led to a significant increase in the serum levels of advanced oxidation protein products (AOPP), mimicking SSc-like features.

Notably, the AOPP levels of mice treated with TwX were substantially lower than that of the healthy animals. Moreover, TwX treatment significantly reduced skin thickness, accumulation of the collagen protein, skin levels of hydroxyproline—an oxidative stress marker, and fibrosis of the skin and lungs.

Overall, these results suggest that TwX may treat SSc by regulating oxidative stress, and reducing skin and lung fibrosis.

(Excerpt) Read more at medicalxpress.com ...


TOPICS: Health/Medicine
KEYWORDS: autoimmune; coq10; cystine; disease; glutamine; immune; lglutamine; niacin; sclerosis; system; twindeex; vitaminb2; vitaminc
Twendee X is a supplement that contains “Vitamin C, L-glutamine, niacin, L-cystine, coenzyme Q10, vitamin B2, succinic acid, and fumaric acid.” It is available at places like Amazon, but the constituents are easy to find and use.

This supplement has been found to be helpful for “ cognition, memory, and motor coordination in mouse models of dementia, and reduction in affected region size, oxidative stress, and inflammation in mouse models of ischemic stroke,” as well.

1 posted on 05/24/2024 9:05:00 AM PDT by ConservativeMind
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To: Mazey; ckilmer; goodnesswins; Jane Long; BusterDog; jy8z; ProtectOurFreedom; matthew fuller; ...

The “Take Charge Of Your Health” Ping List

This high volume ping list is for health articles and studies which describe something you or your doctor, when informed, may be able to immediately implement for your benefit.

Email me to get on either the “Common/Top Issues” (20 - 25% fewer pings) or “Everything” list.

2 posted on 05/24/2024 9:05:32 AM PDT by ConservativeMind (Trump: Befuddling Democrats, Republicans, and the Media for the benefit of the US and all mankind.)
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To: ConservativeMind

Please add me to your ping list. Thank you.


3 posted on 05/24/2024 9:14:43 AM PDT by laplata (They want each crisis to take the greatest toll possible.)
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To: ConservativeMind

Is this Japanese? If so, I may have heard of it.


4 posted on 05/24/2024 9:16:11 AM PDT by Oystir ( )
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To: ConservativeMind

Bookmark


5 posted on 05/24/2024 9:28:16 AM PDT by misanthrope (Deranged, sinister, deplorable troll)
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To: ConservativeMind

Just ordered 2 bottles from Amazon:

https://www.amazon.com/gp/product/B0B8MGH2S1/ref=ppx_yo_dt_b_asin_title_o00_s00?ie=UTF8&psc=1


6 posted on 05/24/2024 9:31:39 AM PDT by Carriage Hill (A society grows great when old men plant trees, in whose shade they know they will never sit.)
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To: ConservativeMind

Aka scleroderma, which I have had 50 years.
Sorry, I don’t believe this. More false hope nonsense


7 posted on 05/24/2024 9:43:12 AM PDT by AuntB (Trump is our Ben Franklin - Brilliant, Boisterous, Brave and ALL AMERICAN!)
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To: ConservativeMind

I wonder HOW MUCH of each supplement is in each tablet. Does not reveal ingredient list like most do.


8 posted on 05/24/2024 9:52:05 AM PDT by goodnesswins (Climate cultists think we should go back to the good times when people starved)
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