New research identifies a threshold of immunity for COVID-19 (Available test for non-vaccinated and vaccinated persons)

Medical Xpress / University College Dublin / Nature Communications ^ | Nov. 6, 2023 | Grace Kenny et al

[ConservativeMind]

How much immunity do we need against COVID-19? New international research has identified a "threshold of immunity" to SARS-CoV-2.

The study has identified strong relationships between Receptor-binding domain (RBD) COVID19 antibodies, and how well humans can neutralize the SARS-CoV-2 virus.

A RBD is a key part of a virus that allows it to dock to body receptors to gain entry into cells, leading to infection. These are also the primary targets in the prevention and treatment of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2)—the virus that causes COVID-19.

This new research, coordinated by Dr. Grace M. Kenny and Sophie O'Reilly from the UCD Centre for Experimental Pathogen Host Research (CEPHR), has demonstrated that a RBD titer of 456 BAU/ml predicts effective neutralization against both wild type and variants of SARS-CoV-2 with high sensitivity and specificity.

The threshold of immunity was validated across three different periods of the COVID-19 pandemic, including pre-vaccination period, post-vaccination period and the more recent period where most people are vaccinated and have been infected (hybrid immunity). The study also validated the findings in an independent cohort of older people from the VACCELERATE EU trial consortium.

Patrick Mallon explained, "This is the first study to identify a minimum level of COVID-19 antibody that confers protection against different strains of the virus. Even with vaccination, some people remain vulnerable to severe COVID-19. RBD level below 456BAU/mL may indicate sub-optimal immunity to SARS-CoV-2 and need for booster vaccination. An RBD of 456 BAU/ml could also be used as a minimum target for effective vaccination. A RBD below the 456 BAU/mL threshold may also help identify people who should be prioritized for COVID19 treatment if they get infected."

[ConservativeMind]

BAU = Binding Antibody Units

Receptor-binding domain (RBD) IgG COVID19 antibodies of 456 BAU/ml means you should be fine against any expected SARS-CoV-2 that comes your way.

If it’s less than that, prepare yourself.

It looks like this test can be ordered by anyone directly from Labcorp for $69.

[ConservativeMind]

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[BrexitBen]

Ivermectin, hydroxychloroquine, nicotine gum and patches.

Far more effective, and far less dangerous, than the clot shots.

[ransomnote]

Snake oil and lies, for $69 from Labcorp

[ConservativeMind]

So ransomnote, you don’t believe anyone gets measurable antibodies that can be tested?

[ConservativeMind]

It’s your decision how to prep, if your numbers are found to be lower than that number.

The scientists spoke to vaccines, but the number and the test are agnostic to what anyone decides to do to prepare for a possible infection.

[ransomnote]

This whole study looks like more scamdemic. Checking the research upon which it is based, the paper references PCR results from Ireland in 2020! They are talking about threshold immunity when they have damaged the immune systems of many in the public. This study is creepy in that it seems to be gearing up to push more vax because their new assessment can tell if people are supposedly, “A quart low” on antigens. When Covid is treatable and not that dangerous...the whole thing reeks.

[ransomnote]

In the General/Chat forum, on a thread titled New research identifies a threshold of immunity for COVID-19 (Available test for non-vaccinated and vaccinated persons), ConservativeMind wrote:

So ransomnote, you don’t believe anyone gets measurable antibodies that can be tested?

Even the 'research' seems to indicate it's uselessness:

' but whether these
thresholds predict sufficient neutralising capacity against variants of concern
(VOCs), and whether this is impacted by vaccine or infection history remains
unclear. '

ransomnote: I read portions of the research and have no idea why they even bothered. It will take more than skimming to understand this tidbit:

ransomnote: I think the article you posted is financially oriented trash. It's more complex than portrayed - you can have the antibodies and yet be immunocompromised. You can lack the antibodies and still have immunity.

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7443809/ 

"Recent reports that antibodies to SARS-CoV-2 are not maintained in the serum following recovery from the virus have caused alarm. However, the absence of specific antibodies in the serum does not necessarily mean an absence of immune memory. Here, we discuss our current understanding of the relative contribution of B cells and T cells to immunity to SARS-CoV-2 and the implications for the development of effective treatments and vaccines for COVID-19."

ransomnote: I wonder why they're still pretending there aren't successful treatments for Covid, and ignoring natural immunity etc. What a shock it will be when the vaccine lobby has to admit safe effective treatments existed throughout the scamdemic and the 'vaccines' were actually gene therapy, and neither safe nor effective.

[ransomnote]

Below I'll list all the pharmas that  provided support for this research. The whole approach seems bizarre, as if there's tacit admission that 'okay the shots damage your immune system but we have an app for that.' Just test to see where you  are in antigens....) uhm....no, just no.

Here's the documented 'full disclosure' of this research's support from the pharmas (Gilead, Pfizer, Sanofi, Abbot Labs, Astrazenecia, BioRad,) and I don't recognize a lot of the foreign pharmas. Bought and paid for by  our friends at Pfizer etc. Nah...

Competing interests
E.F. has received consulting fees from Gilead, ViiV and Vidacare Ireland,
and has been awarded a grant from Science Foundation Ireland outside
the submitted work. E.d.B. has received consulting fees from Sanofi
Pasteur and an honoraria/travel grant from Pfizer. P.M. has received
honoraria and/or travel grants from Gilead Sciences, MSD, Astrazeneca,
and ViiV Healthcare, and has been awarded grants by Science Foun-
dation Ireland outside the submitted work. P.K. reports grants or con-
tracts from German Federal Ministry of Research and Education (BMBF)
B-FAST (Bundesweites Forschungsnetz Angewandte Surveillance und
Testung) and NAPKON (Nationales Pandemie Kohorten Netz, German
National Pandemic Cohort Network) of the Network University Medicine
(NUM) and the State of North Rhine-Westphalia; Consulting fees Ambu
GmbH, Gilead Sciences, Mundipharma Research Limited, Noxxon N.V.
and Pfizer Pharma; Honoraria for lectures from Akademie für Infek-
tionsmedizin e.V., Ambu GmbH, Astellas Pharma, BioRad Laboratories
Inc., Datamed GmbH, European Confederation of Medical Mycology,
Gilead Sciences, GPR Academy Ruesselsheim, HELIOS Kliniken GmbH,
Lahn-Dill-Kliniken GmbH, medupdate GmbH, MedMedia GmbH, MSD
Sharp & Dohme GmbH, Pfizer Pharma GmbH, Scilink Comunicación
Científica SC, streamedup! GmbH and University Hospital and LMU
Munich; Participation on an Advisory Board from Ambu GmbH, Gilead
Sciences, Mundipharma Research Limited and Pfizer Pharma; A pending
patent currently reviewed at the German Patent and Trade Mark Office
(DE 10 2021 113 007.7); Other non-financial interests from Elsevier, Wiley
Article https://doi.org/10.1038/s41467-023-42717-1
Nature Communications | (2023)14:7015 10
and Taylor & Francis online outside the submitted work. J.S. has received
research support from the German Federal Ministry of Education and
Research (BMBF) and Basilea Pharmaceuticals Inc.; has received speaker
honoraria by Pfizer Inc., Gilead, and AbbVie; has been a consultant to
Gilead, Produkt&Markt GmbH, Alvea Vax. and Micron Research and has
received travel grants by German Society for Infectious Diseases (DGI
e.V.) and Meta-Alexander Foundation. O.A.C. reports grants or contracts
from BMBF, Cidara, EU-DG RTD (101037867), Pfizer; Consulting fees from
Biocon, Biosys, Janssen, Noxxon, Pfizer; Honoraria for lectures from
Gilead, MedScape, Merck/MSD, Pfizer; Participation on a Data Safety
Monitoring Board or Advisory Board from Cidara, Janssen. A.L. receives
consulting fees from Abbott and is co-chair of the Gilead Research
Scholars Programme. All other authors declare no competing interests.

[grey_whiskers]

Anyone else catch the pro-clotshot sleight of hand?

Hint: there’s an earlier study in Nature:Medicine (IIRC) from years ago where they investigated antibodies to other parts of the virus besides the RBD, some not on the spike at all.

According to the interpretation I read, about 80% of people are immune to COVID already because of crossover immunity to other viruses (one of the groups tested was people who had never been exposed to COVID and yet had antibodies which reacted strongly to a number of COVID-1984 proteins. Some of the proteins were nucleocapsid proteins, therefore highly conserved—the variants will not quickly drift *or* evolve (selection pressure) away from them

There may be other objections to this article later, but I need to go to bed.

[HIDEK6]

How much grant money did these clowns rake in for “investigating” an imaginary disease?

[Salamander]

Oh look.

Yet another thing I’ll not be partaking of.

[Maskot]

I saw a TV commercial the other day (and actually recorded it on my phone) for the newest and bestest fauxinne out there, Spikevax. Yes, you read that right, Spikevax. The list of possible side effects was phenomenal. I was completely blown away! It’s like they’re admitting it now

[MayflowerMadam]

“Spikevax. The list of possible side effects was phenomenal.”

So “SAFE and effective” is not there now?

[Maskot]

Nope. I was actually surprised the commercial didn’t say, “Although side effects can happen, it’s still safer and more effective to get your Spikevax ™️ today! Visit your nearest Walgreens or cvs stock boy to administer yours!”

[mewzilla]

Were supposed to take Deep State’s word for this...?

SNORT.

[Candor7]

Ivermectin, hydroxychloroquine, nicotine gum and patches.

Far more effective, and far less dangerous, than the clot shots.>>>>>>>>>>>>>>>>>

*****************************

Agreed Full stop, all you have to do is take 30 minutes and educate yourself right here:

https://covid19criticalcare.com/

The trick is to raise the solution of Ivermectin \ per unit blood to 60 nanograms per liter of blood for a period of 5 to 7 days. Kills all Covid 19 and variants.Take dosages withing first few days of being infected along with zinc...dosage charts on site per body weight.

[trebb]

Blah blah blah - when they talk about “hybrid immunity” you know it’s just another ploy for those who still cower in the corner to cough up more money for “peace of mindlessness”.

[DSH]

Blah blah blah - when they talk about “hybrid immunity” you know it’s just another ploy for those who still cower in the corner to cough up more money for “peace of mindlessness”.

Exactly. One either understands that the medical industry today is purely and simply a scam and a money grab, or one doesn't.

After all that has happened over the past three years, one would think that everybody would have wised up to that reality.

[Salamander]

I wish I could still find that sarcastic “ad” for the “sad little ovoid”where the hilarious list of side effects gets crazier , scrolls increasingly faster until you see the manically grinning ovoid fly across the screen and hear what sounds like a plane crash out of sight.

Funniest sarcasm ever.