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Conflicting Evidence Of mRNA Technology Raises Serious Concerns About Rush For Use In New Vaccine Development
Epoch Times ^ | 09/01/2023 | Megan Redshaw

Posted on 09/01/2023 7:27:10 PM PDT by SeekAndFind

The U.S. government and pharmaceutical companies are investing a substantial amount to develop new mRNA vaccines for infectious diseases and cancer, fueling a lucrative mRNA platform valued at $136.2 billion.

A newly established White House program announced on Aug. 23 that it is granting a total of $25 million over three years to Emory University, Yale School of Medicine, and the University of Georgia to develop personalized therapeutic vaccines against cancers and emerging infections, similar to how COVID-19 mRNA vaccines target SARS-CoV-2. They aim to use mRNA—an essential element in COVID-19 vaccines developed to prevent SARS-CoV-2 infections—to program a unique class of immune cells called dendritic cells to initiate a desired immunological response.

Pharmaceutical companies such as Moderna, BioNTech, and CureVac are conducting clinical trials using mRNA-based vaccines with advanced melanoma, ovarian, colorectal, and pancreatic cancers. The National Institutes of Health is partnering with BioNTech to develop a personalized vaccine for pancreatic cancers. In addition to COVID-19 and cancer, other mRNA-based vaccines in development target influenza, genital herpes, respiratory viruses, and shingles.

Although mRNA platforms are appealing because they reduce costs and shorten the vaccine development timeline, evidence and experience suggest the mRNA technology used for novel COVID-19 vaccines is associated with various harms and neither prevents COVID-19 nor its transmission.

Evidence Challenging Vaccine ‘Safe and Effective’ Narrative

The unprecedented rates of adverse events following COVID-19 vaccination overshadow the benefits, according to researchers from Australia who say the SARS-CoV-2 spike protein, whether from the virus or created from genetic code in mRNA and adenovectorDNA vaccines, is toxic and causes a wide array of diseases.

In their recently published paper published in Biomedicines titled, “‘Spikeopathy’: COVID-19 Spike Protein Is Pathogenic, from Both Virus and Vaccine mRNA,” the researchers explored peer-reviewed data countering the “safe and effective” narrative attached to new technologies used to develop mRNA and adenovectorDNA vaccines at “warp speed” to end the pandemic.

Spike protein pathogenicity, termed “spikeopathy,” describes the ability of the spike protein to cause disease, and the researchers say it can affect many organ systems.

Researchers noted the following key problem areas:

Now that vaccines utilizing mRNA technology have been available and widely distributed for several years, data show these vaccines produce foreign antigens in human tissues and increase the risk of autoimmune, neurological, cardiovascular, inflammatory disorders, and cancers, especially when the vaccine ingredients do not remain localized at the injection site. An antigen is any substance that stimulates an immune response. If the immune system encounters an antigen that is not found on the body’s own cells, it will launch an attack against that antigen.

Pharmacokinetic and pharmacodynamic data show the design of the mRNA and adenovectorDNA COVID-19 vaccines allow uncontrolled biodistribution, durability, and persistent bioavailability of the spike protein inside the body after vaccination. Pharmacokinetics is the study of how the body interacts with administered substances for the entire duration of exposure. Pharmacodynamics assesses the drug’s effect on the body more closely.

This may explain the unprecedented number of adverse events that appear to be associated with the spike protein produced by the gene-based technologies employed by Pfizer, Moderna, AstraZeneca, and Johnson & Johnson, as well as the viral vector DNA technology used by other countries, researchers said.

mRNA Vaccines Are Gene Therapy and May Cause Harm

Gene-based COVID-19 vaccines are therapeutic products that actually fit within the FDA’s definition of gene therapy because they cause the cells of the vaccinated person to produce antigens for transmembrane expression that invokes an immune response. By design, these novel vaccine platforms risk tissue damage secondary to autoimmune responses raised against cells expressing foreign spike antigens, researchers said.

The FDA was aware of the pathogenicity of spike proteins before releasing COVID-19 vaccines to the public. In an October 2022 meeting with its vaccine advisors, the FDA presented a highly accurate list of potential adverse events associated with COVID-19 vaccines, including neurological, cardiovascular, and autoimmune “possible adverse events.”

React19, an organization that provides financial, emotional, and physical support to those experiencing long-term injuries from COVID-19 vaccines, provided a list of over 3,400 published papers and case reports of injuries affecting more than 20 organ systems. More than 432 peer-reviewed papers relate to papers and case reports of myocarditis, cardiomyopathy, myocardial infarction, hypertension, aortic dissection, postural orthostatic tachycardia syndrome (POTS), tachycardia, and conduction disturbance—a problem with the electrical system that controls the heart’s rate and rhythm.

The most common group of adverse events reported following COVID-19 vaccination to both pharmacovigilance databases and Pfizer involve neurological disorders. According to the paper, neurological symptoms and cognitive decline with accelerated neurodegenerative disease are features of acute COVID-19 vaccine injuries and, to some extent, long COVID syndrome. Research suggests (pdf) LNPs transporting the mRNA to make spike proteins can cross the blood-brain barrier and cause neurotoxic effects.

Lipid Nanoparticles Are Toxic and Pro-Inflammatory

It’s not just the spike protein that can cause disease. LNPs that serve as the delivery method are also toxic and pro-inflammatory.

Research from 2018 showed even small amounts of nanoparticles taken up by the lungs can lead to cytotoxic effects. Ingested nanoparticles have been shown to affect lymph nodes, the liver, and the spleen, while when injected as a drug carrier, they can pass any barrier and translocate to the brain, ovaries, and testes, mainly after phagocytosis by macrophages, which help distribute them across the body. The effects on the reproductive system suggest lipid nanoparticles can be cytotoxic and damage DNA.

According to the authors, two components in the mRNA lipid nanoparticle complexes, ALC-0315 and ALC-0159, are concerning, as they have never been used in a medicinal product and are not registered in either the European Pharmacopoeia or in the European C&L Inventory database. A question posed to the European Parliament in December 2021 pointed out that the manufacturer of the nanoparticles specifies the nanoparticles are for research only and not for human use. The European Commission responded that the excipient in Pfizer’s Comirnaty vaccine “has been demonstrated to be appropriate … in compliance with the relevant EMA scientific guidelines and standards.”

Still, this could explain the root cause of numerous post-vaccination adverse events, researchers said.

Read more here...


TOPICS: Health/Medicine; Science; Society
KEYWORDS: antivaxxers; covid; mrna; safelydefective; vaccinedevelopment; vaccines; wewereright

1 posted on 09/01/2023 7:27:10 PM PDT by SeekAndFind
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To: SeekAndFind

My motto: JUST SAY NO.


2 posted on 09/01/2023 7:28:57 PM PDT by Howie66 ("Biden-Fetterman 2024. It's A No Brainer")
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To: SeekAndFind

We have to pass a vaccine mandate to see what’s in it.


3 posted on 09/01/2023 7:34:55 PM PDT by Huskrrrr (Alinsky, you magnificent Bastard, I read your book!)
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To: SeekAndFind

they will need an EUA so they can avoid legal liability


4 posted on 09/01/2023 7:40:03 PM PDT by joshua c (to disrupt the system, we must disrupt our lives, cut the cable tv)
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To: Huskrrrr

We have to genetically alter ourselves to see if it was for the better or worse. We’ll go down in history as part of The Great Experiment.


5 posted on 09/01/2023 8:00:21 PM PDT by BipolarBob (I told my coach that the letters M and E are in team and he didn't like it.)
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To: SeekAndFind

Conflicting evidence???

How about informed consent based on longitudinal studies. OH! That’s right! There are no longitudinal studies. In fact, the FDA and Pharma tried to HIDE what information was available for 75 YEARS.

When judges ruled they could not hide, all sorts of facts were revealed. One of the most disturbing was the miscarriages due to the vaccine.

Just evil.


6 posted on 09/01/2023 8:04:56 PM PDT by Ronaldus Magnus III (Do, or do not, there is no try)
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To: Huskrrrr

Exactly


7 posted on 09/01/2023 8:11:33 PM PDT by SaveFerris (Luke 17:28 ... as it was in the days of Lot; they did eat, they drank, they bought, they sold ......)
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To: BipolarBob

(We’ll go down in history as part of The Great Experiment.)

The Great Reset

Population Reduction


8 posted on 09/01/2023 8:12:23 PM PDT by SaveFerris (Luke 17:28 ... as it was in the days of Lot; they did eat, they drank, they bought, they sold ......)
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bbb


9 posted on 09/02/2023 3:46:16 AM PDT by thinden (buckle up ....)
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To: SeekAndFind

I am concerned that it appears that all vaccines will be replaced by MRNA vaxxines. This whole covid mess has already convinced me that I must not consent to any injections of anything for any reason. Too many influential people like Bill Gates are talking openly about putting MRNA in all medications and in the food supply. I think it already goes into beef and pork. Alas I do not have the resources to buy and develop the land to raise my own food and not participate in the depopulation drive.


10 posted on 09/02/2023 5:45:53 AM PDT by arthurus (* covfefe k)
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To: SeekAndFind

A blockbuster study, this one. It demolishes 30 years of mRNA drug research and declares Robert Malone’s lipid packaging discovery to be outright dangerous. Malone won’t be happy to learn that!

MDPI, the parent company of the Biomedicines journal that this is the source of this article, publishes 428 “journals”.

These are online only journals and it appears that MDPI lets you invent new journals, probably explaining why there are 428 of them.

And authors pay MDPI to have their studies “peer reviewed” by someone at MDPI and published. I don’t think that’s what peer review means in normal usage.

Uncharitable critics might call this a pay to play operation having dubious value.

Somehow Nature gets by with one journal. Go figure.


11 posted on 09/02/2023 6:32:54 AM PDT by Pelham (President Eisenhower. Operation Wetback 1953-54)
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To: arthurus

The Covid virus uses its own native mRNA to get your cells to be little virus factories.

Somehow that mRNA never seems to get the jab critics in a panic.

Apparently there is the “who cares” mRNA found all throughout nature, including in pathogens that want to kill us, and the scary super duper dangerous mRNA used to generate medicine.


12 posted on 09/02/2023 6:46:32 AM PDT by Pelham (President Eisenhower. Operation Wetback 1953-54)
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