Posted on 08/27/2023 9:09:08 AM PDT by ConservativeMind
Research has found that the hormone testosterone may play an important role in the development of endometrial cancer.
The discovery raises exciting new possibilities for screening, preventing and fighting this increasingly prevalent disease.
Endometrial cancer is the fourth most common cancer in Australian women and its incidence is rising. Yet treatment options are limited, with a hysterectomy often the first line of defense.
The new study by gives hope that existing hormone therapies may offer another option.
"Everyone has testosterone, but our research suggests that women with higher levels of the hormone are at greater risk of developing endometrial cancer," said A/Prof O'Mara.
"In establishing an independent relationship between testosterone and endometrial cancer, the study opens up potential new avenues for treatment.
"We're really excited by these findings and hope that with further research, we might be able to treat endometrial cancer by targeting or inhibiting testosterone with existing drugs."
In the study, the researchers carried out advanced genetic analysis to identify five independent risk factors for endometrial cancer. These risk factors include body weight, age at onset of menstruation and menopause, and testosterone levels.
The testosterone connection was related to a specific region of the human genome which the study discovered has links to a higher risk of endometrial cancer.
"It is very promising to see testosterone levels emerge so strongly as a likely risk factor, because a person's testosterone can be modified," O'Mara said.
"There are already approved drugs designed to block and counteract the hormone's effects. Further research may justify trying to repurpose those drugs to help women with endometrial cancer.
"It is really important that we do find more therapeutic options, as the current first line treatment for endometrial cancer is a hysterectomy. This is obviously highly invasive, and affects fertility in younger patients."
(Excerpt) Read more at medicalxpress.com ...
I’m guessing you have stock in this Xpress place? It’s like a dozen articles/day that hardly no one replies to....it’s getting old fast.
Testosterone levels have been dropping in men ever since it’s been recorded. We are half the level of men thousands of years ago (as determined by skull size). Now they want to drop them lower for nefarious reasons.
If it’s getting old, stop reading them.
235 of your fellow Free Republic posters apparently want these articles—regardless of them typing something into each thread.
How many people have ever said they cared about getting notice about your postings?
Yeah, I thought so.
How many men have you known who had endometrial cancer?
None. What’s your point?
What in this study write up made you think about reducing men’s testosterone?
Have you read the headline?
Well, you are Bipolar.
Not so great for women. Extremely great for men.
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