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Researchers find a connection between plasma lipid profile and severity of COVID-19 (Low triglycerides and/or high cholesterol is preventative)
Medical Xpress / Australian Nuc Science and Tech Org (ANSTO) / Jrnl of Colloid and Interface Science ^ | June 30, 2023 | Yubexi Correa et al

Posted on 07/01/2023 8:03:16 PM PDT by ConservativeMind

In the latest research, investigators gained insights into how the SARS-CoV-2 spike protein (S protein) impacts with lipid metabolism in the body with implications for COVID-19 infection and mRNA vaccination.

The interaction between the S protein and the high-density lipoprotein (HDL) might also contribute to the adverse effects observed in some individuals following mRNA COVID-19 vaccination.

This omega-6 fatty acid is one of two essential polyunsaturated fatty acids. It had been shown previously that the polyunsaturated fatty acid binds to the novel coronavirus SARS-CoV-2 and effectively interferes with binding to a key receptor.

Previous studies had shown that the S protein can remove lipids from model membranes and interfere with lipid removal and exchange processes carried out by HDL.

The latest results suggested that the S protein from the SARS-CoV-2 virus has a stronger ability to remove cholesterol and polyunsaturated lipids compared to saturated and monounsaturated lipids.

Neutron reflectometry experiments revealed the integrity and composition of lipid bilayers when exposed to the S protein and/or HDL.

The study showed that the S protein changes HDL function in a manner that depends on the lipid serum profile of a person.

The results indicated that individuals with low triglycerides and high cholesterol serum levels profile should have a lower tendency to have their lipid metabolism hijacked by the SARS-CoV-2 virus and could present a weaker interaction with the S protein upon COVID-19 illness or vaccination against COVID-19.

The research suggested the S protein may bind to the HDL, potentially interfering with its normal function. The S protein, which is present on the virus surface, may use the same interaction pathway that HDL uses to interact with specific cell membrane receptors.

This interaction between the S protein and HDL may contribute to the adverse effects observed in some individuals following mRNA COVID-19 vaccination.

(Excerpt) Read more at medicalxpress.com ...


TOPICS: Health/Medicine
KEYWORDS: covid; longcovid; vaccination
Low triglycerides and/or high cholesterol (the write up doesn’t clarify that, well) helps prevent COVID-19.

This connection appears to explain some issues with people handling the COVID-19 vaccine, as well, but that may just be related to early results and not long COVID.

1 posted on 07/01/2023 8:03:16 PM PDT by ConservativeMind
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To: Mazey; ckilmer; goodnesswins; Jane Long; BusterDog; jy8z; ProtectOurFreedom; matthew fuller; ...

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2 posted on 07/01/2023 8:04:10 PM PDT by ConservativeMind (Trump: Befuddling Democrats, Republicans, and the Media for the benefit of the US and all mankind.)
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To: ConservativeMind

It’s been established for years low triglycerides and high HDL helps fight inflammation.


3 posted on 07/01/2023 8:10:56 PM PDT by BipolarBob (The battery on my quantum computer is dying. I'm not sure where to find a replacement.)
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To: ConservativeMind

No connection between a protocol which kills people and people dying.


4 posted on 07/01/2023 8:15:55 PM PDT by bray
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