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The “Cucumber Cure”: A Seafood Solution to Diabetes?
Scitech Daily ^ | JUNE 15, 2023 | By UNIVERSITY OF SOUTH AUSTRALIA

Posted on 06/15/2023 11:45:47 AM PDT by Red Badger

Braised Sea Cucumber Food

New research from the University of South Australia suggests that sea cucumbers, a marine delicacy loved across Asia, could play a significant role in preventing diabetes. The study revealed that processed dried sea cucumber with salt extracts can inhibit the formation of Advanced Glycation End products (AGEs), compounds associated with an increased risk of diabetes and its complications, such as heart disease, Alzheimer’s, Parkinson’s, kidney disease, and cancer.

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A new study reveals that sea cucumbers can inhibit the formation of a compound linked to an increased risk of diabetes. The research opens possibilities for the development of a functional food to prevent the onset of the disease and its complications.

They’re a marine delicacy loved across Asia, but the humble sea cucumber is also proving to be a key ingredient in preventing diabetes, according to new research from the University of South Australia.

Exploring the medicinal properties of sea cucumbers (Holothuria scabra), researchers found that processed dried sea cucumber with salt extracts can inhibit a compound that is associated with increased risk of diabetes, thereby reducing the likelihood of the disease.

To date, there is no commercially available therapeutic agent to inhibit the formation of this compound, called Advanced Glycation End product (AGE).

AGEs form when proteins and/or fats combine with sugars in the bloodstream. When accumulated in high levels, they increase diabetic complications, including heart disease, Alzheimer’s, Parkinson’s, kidney disease, and cancer.

Sea Cucumber

The bioactive compounds in sea cucumbers could protect against Type 2 Diabetes. Credit: “Garlic bread sea cucumber (Holothuria scabra)” by wildsingapore

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Lead researcher, UniSA’s Dr. Permal Deo, says understanding how the bioactive compounds in sea cucumbers can inhibit AGEs could protect against these diseases.

We know that an accumulation of AGEs is associated with complications of type 2 diabetes, so strategies to prevent this may reduce the risk of developing diabetic complications,” Dr. Deo says.

“Biologically active novel compounds in medicinal plants and foods are potential therapeutic agents to prevent diabetic complications.

“Sea cucumbers are known to have a range of therapeutic properties, including anti-inflammatory and antioxidant properties, so we wanted to explore their bioactive compounds as AGE inhibitors.

“We found that processed dried sea cucumber with salt extracts and collagen can significantly inhibit AGEs by lowering a range of sugar-related metabolites in the body and reducing the risk of diabetes.”

In Australia, almost 1.3 million people have type 2 diabetes. Globally, about 422 million people have diabetes, with 1.5 million deaths directly attributed to the disease each year.

Almost 60 percent of all cases of type 2 diabetes can be delayed or prevented with changes to diet and lifestyle.

“These results provide sound evidence that sea cucumbers could be developed as a functional food product to help battle the onset of diabetes and diabetic-complications.”

Reference:

“Holothuria scabra Jaegar 1833 (Sandfish) extracts and collagens modulate protein-bound Nε-carboxymethyllysine, Nε-carboxyethyllysine and methylglyoxal-derived hydroimidazolone-1 levels”

by Hoi Y. Wong, Emma L. Jaunay, Wai C. D. Lau, Brock Peake, Ravinesh Ram, Paul C. Southgate and Permal Deo,

10 February 2023

International Journal of Food Science & Technology.

DOI: 10.1111/ijfs.16341


TOPICS: Food; Health/Medicine; Military/Veterans; Pets/Animals
KEYWORDS: sashimi; sushi
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To: married21

You are quite welcome.


21 posted on 06/15/2023 1:48:41 PM PDT by GaltAdonis
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To: Red Badger

Maybe “Balance of Nature” will put some dried sea cucumber in three of their pills.


22 posted on 06/15/2023 3:47:07 PM PDT by jonrick46 (Leftniks chase illusions of motherships at the end of the pier.)
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To: Red Badger

I’ll stay with the Metformin - thanks anyway ...


23 posted on 06/15/2023 8:29:27 PM PDT by 11th_VA (XX < > XY)
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