Posted on 03/28/2023 1:33:21 PM PDT by ConservativeMind
For the first time, researchers have developed a form of the omega-3 fatty acid docosahexaenoic acid (DHA) that is capable of crossing into the eye's retina to ward off visual declines related to Alzheimer's disease, diabetes and other disorders.
The DHA found in fish oil capsules is called triacylglycerol (TAG) DHA. Although TAG-DHA has benefits in other parts of the body, it does not reach the eyes. For the study, researchers created a new lysophospholipid form of DHA, or LPC-DHA. In studies using mice, LPC-DHA successfully increased DHA in the retina and reduced eye problems associated with Alzheimer's-like processes.
In healthy eyes, DHA is concentrated in the retina, where it helps maintain photoreceptors, the cells that convert light into signals that are sent to the brain. DHA deficiency in the retina is associated with vision loss. People with Alzheimer's disease, as well as those with diabetes, retinitis pigmentosa, age-related macular degeneration and peroxisomal disorders, frequently have abnormally low levels of retinal DHA, and visual impairments are common as a result.
"Increasing the retinal DHA at clinically feasible doses has not been possible until now because of the specificity of the blood-retinal barrier that is incompatible with the specificity of the intestinal barrier," said Dhavamani.
The researchers tested their LPC-DHA supplement in mice bred to exhibit early-onset Alzheimer's disease. After six months, mice that were fed LPC-DHA daily showed a 96% improvement in retinal DHA content as well as preserved retinal structure and function. In contrast, TAG-DHA supplements had no effect on retinal DHA levels or function.
The dosage of LPC-DHA used in the study is equivalent to about 250 to 500 milligrams of omega-3 fatty acids per day in humans.
(Excerpt) Read more at medicalxpress.com ...
Many thanks for the info!!!
Liposomes are fatty transport molecules (used in covid vaccines actually) not LPC-DHA
It’s not on the market in the US yet.
Me, too. My AMD manifests itself as a retinal “pucker” on my right retina that causes visual distortion and loss of acuity. It’s essentially a scar tissue that has formed on the retina.
I had my doctor of an Omega-3 Index test and my results were low which enhances my risk of heart attack. I recently started taking Krill Oil supplements for the condition as well as increasing my intake of salmon.
So this research is of immense interest to me.
More on roe for Omega-3, here:
https://novoslabs.com/what-are-the-best-omega-3-supplements-a-guide/
Lumpfish roe is the cheapest.
I agree:
https://www.lysoveta.com/industry#collaboration
It seems to made in small batches, now, but another post shows that some fish roe has a high amount of the very same Omega-3 fats.
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